Research in Computational Molecular Biology | |
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Frequency | Annually |
Location(s) | Cambridge, Massachusetts, United States (2024) |
Years active | 27 |
Previous event | RECOMB 2024 |
Next event | RECOMB 2025 |
Organised by | Massachusetts Institute of Technology and Tufts University |
Website | recomb |
Research in Computational Molecular Biology (RECOMB) is an annual academic conference on the subjects of bioinformatics and computational biology. The conference has been held every year since 1997 and is widely considered as one of two best international conferences in computational biology publishing rigorously peer-reviewed papers, alongside the ISMB conference. The conference is affiliated with the International Society for Computational Biology. Since the first conference, authors of accepted proceedings papers have been invited to submit a revised version to a special issue of the Journal of Computational Biology . [1]
RECOMB was established in 1997 by Sorin Istrail, Pavel Pevzner and Michael Waterman. The first conference was held at the Sandia National Laboratories in Santa Fe, New Mexico. [2]
A series of RECOMB Satellite meetings was established by Pavel Pevzner in 2001. These meetings cover specialist aspects of bioinformatics, including massively parallel sequencing, comparative genomics, regulatory genomics and bioinformatics education. [3] Today, it consists of focused meetings covering various specialized aspects of bioinformatics.
As of RECOMB 2010, the conference has included a highlights track, modelled on the success of a similar track at the ISMB conference. The highlights track contains presentations for computational biology papers published in the previous 18 months. [2] [4]
As of 2016 the conference started a partnership with Cell Systems. Each year, a subset of work accepted at RECOMB is also considered for publication in a special issue of Cell Systems devoted to RECOMB. Other RECOMB papers are invited for a short synopsis (Cell Systems Calls) in the same issue. More recently, RECOMB has also partnered with Genome Research to publish revised version of subset of RECOMB-accepted papers. [5]
The RECOMB Steering Committee [6] currently includes Bonnie Berger (chair), Vineet Bafna, Eleazar Eskin, Jian Ma, Teresa Przytycka, Cenk Sahinalp, Roded Sharan, and Martin Vingron.
Bioinformatics is an interdisciplinary field of science that develops methods and software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics uses biology, chemistry, physics, computer science, computer programming, information engineering, mathematics and statistics to analyze and interpret biological data. The process of analyzing and interpreting data can sometimes be referred to as computational biology, however this distinction between the two terms is often disputed. To some, the term computational biology refers to building and using models of biological systems.
Computational biology refers to the use of techniques in computer science, data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and data science, the field also has foundations in applied mathematics, molecular biology, cell biology, chemistry, and genetics.
Computational genomics refers to the use of computational and statistical analysis to decipher biology from genome sequences and related data, including both DNA and RNA sequence as well as other "post-genomic" data. These, in combination with computational and statistical approaches to understanding the function of the genes and statistical association analysis, this field is also often referred to as Computational and Statistical Genetics/genomics. As such, computational genomics may be regarded as a subset of bioinformatics and computational biology, but with a focus on using whole genomes to understand the principles of how the DNA of a species controls its biology at the molecular level and beyond. With the current abundance of massive biological datasets, computational studies have become one of the most important means to biological discovery.
Michael Spencer Waterman is a Professor of Biology, Mathematics and Computer Science at the University of Southern California (USC), where he holds an Endowed Associates Chair in Biological Sciences, Mathematics and Computer Science. He previously held positions at Los Alamos National Laboratory and Idaho State University.
Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the conference is on the development and application of advanced computational methods for biological problems. The conference has been held every year since 1993 and has grown to become one of the largest and most prestigious meetings in these fields, hosting over 2,000 delegates in 2004. From the first meeting, ISMB has been held in locations worldwide; since 2007, meetings have been located in Europe and North America in alternating years. Since 2004, European meetings have been held jointly with the European Conference on Computational Biology (ECCB).
Eugene Wimberly "Gene" Myers, Jr. is an American computer scientist and bioinformatician, who is best known for contributing to the early development of the NCBI's BLAST tool for sequence analysis.
The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide.
Bioinformatics is a biweekly peer-reviewed open-access scientific journal covering research and software in bioinformatics and computational biology. It is the official journal of the International Society for Computational Biology (ISCB), together with PLOS Computational Biology.
Lawrence E. Hunter is a Professor and Director of the Center for Computational Pharmacology and of the Computational Bioscience Program at the University of Colorado School of Medicine and Professor of Computer Science at the University of Colorado Boulder. He is an internationally known scholar, focused on computational biology, knowledge-driven extraction of information from the primary biomedical literature, the semantic integration of knowledge resources in molecular biology, and the use of knowledge in the analysis of high-throughput data, as well as for his foundational work in computational biology, which led to the genesis of the major professional organization in the field and two international conferences.
Pavel Arkadevich Pevzner is the Ronald R. Taylor Professor of Computer Science and director of the NIH Center for Computational Mass Spectrometry at University of California, San Diego. He serves on the editorial board of PLoS Computational Biology and he is a member of the Genome Institute of Singapore scientific advisory board.
The International Society for Computational Biology Student Council (ISCB-SC) is a dedicated section of the International Society for Computational Biology created in 2004. It is composed by students and young researchers from all levels in the fields of bioinformatics and computational biology. The organisation promotes the development of the students' community worldwide by organizing different events including symposia, workshops, webinars, internship coordination and hackathons. A special focus is made on the development of soft skills in order to develop potential in bioinformatics and computational biology students around the world.
The European Conference on Computational Biology (ECCB) is a scientific meeting on the subjects of bioinformatics and computational biology. It covers a wide spectrum of disciplines, including bioinformatics, computational biology, genomics, computational structural biology, and systems biology. ECCB is organized annually in different European cities. Since 2007, the conference has been held jointly with Intelligent Systems for Molecular Biology (ISMB) every second year. The conference also hosts the European ISCB Student Council Symposium. The proceedings of the conference are published by the journal Bioinformatics.
SPAdes is a genome assembly algorithm which was designed for single cell and multi-cells bacterial data sets. Therefore, it might not be suitable for large genomes projects.
Ron Shamir is an Israeli professor of computer science known for his work in graph theory and in computational biology. He holds the Raymond and Beverly Sackler Chair in Bioinformatics, and is the founder and former head of the Edmond J. Safra Center for Bioinformatics at Tel Aviv University.
Alfonso Valencia is a Spanish biologist, ICREA Professor, current director of the Life Sciences department at Barcelona Supercomputing Center, of Spanish National Bioinformatics Institute (INB-ISCIII), and coordinator of the data pillar of the Spanish Personalised Medicine initiative, IMPaCT. From 2015 to 2018, he was President of the International Society for Computational Biology.
Gary Stormo is an American geneticist and currently Joseph Erlanger Professor in the Department of Genetics and the Center for Genome Sciences and Systems Biology at Washington University School of Medicine in St Louis. He is considered one of the pioneers of bioinformatics and genomics. His research combines experimental and computational approaches in order to identify and predict regulatory sequences in DNA and RNA, and their contributions to the regulatory networks that control gene expression.
The Bioinformatics Open Source Conference (BOSC) is an academic conference on open-source programming and other open science practices in bioinformatics, organised by the Open Bioinformatics Foundation. The conference has been held annually since 2000 and is run as a two-day meeting either within Intelligent Systems for Molecular Biology (ISMB) conference or as a joint conference with the Galaxy community.
Núria López Bigas is a Spanish biologist and research professor with expertise in medical genetics, computational biology, and bioinformatics. She is an ICREA professor at Pompeu Fabra University and she also leads the Biomedical Genomics Research Group at the Institute for Research in Biomedicine in Barcelona, Spain. Her research is focused on developing computational approaches to investigate cancer genomes.
Vineet Bafna is an Indian bioinformatician and professor of computer science and director of bioinformatics program at University of California, San Diego. He was elected a Fellow of the International Society for Computational Biology (ISCB) in 2019 for outstanding contributions to the fields of computational biology and bioinformatics. He has also been a member of the Research in Computational Molecular Biology (RECOMB) conference steering committee.