Barossa Valley Way is the main road linking most of the major towns of the Barossa Valley in South Australia, designated as route B19 for its entire length. It is 35 km long, roughly following the North Para River.
Riddoch Highway is a rural highway in south-eastern South Australia, designated as route A66 between Keith and Mount Gambier, with the remainder between Mount Gambier and Port MacDonnell designated as route B66. It is named after John Riddoch, the first white settler landholder and vigneron in Coonawarra.
Flinders Highway connects the South Australian towns of Ceduna and Port Lincoln, a distance of 396 kilometres (246 mi) Flinders Highway – along with Lincoln Highway – presents an alternative but somewhat longer coastal route between Ceduna and Port Augusta, compared to the more direct route along Eyre Highway. It is designated route B100.
Tod Highway is an important 177 kilometre highway serving South Australia's Eyre Peninsula's wheatbelt, and is designated route B90. It is named after Robert Tod who explored the area in 1839.
Southern Ports Highway is a 119 kilometres rural highway in South Australia that connects Kingston SE with Millicent via Rendelsham, Southend, Beachport and Robe. It is a former alignment of Princes Highway, bypassed in 1933.
Goyder Highway (B64) is a west–east link through the Mid North region of South Australia connecting Spencer Gulf to the Riverland. It is part of the most direct road route from Port Augusta to much of Victoria and southern New South Wales.
Augusta Highway is the part of Australia's ring route located in South Australia between Port Wakefield and Port Augusta.
Thiele Highway is a road in South Australia connecting the outskirts of Adelaide to the North west bend of the Murray River at Morgan, South Australia. It is named after author Colin Thiele who lived most of his life in towns along the route, and set some of his stories in the area.
Worlds End Highway is a road in the Yorke and Mid North region of South Australia running north from Eudunda through Robertstown to Goyder Highway 18 km southeast of Burra. The northern terminus of the highway is in a locality named Worlds End, leading to the name of the highway.
Flinders Ranges Way is the main road route through the Flinders Ranges in South Australia. It starts from the Augusta Highway at Stirling North, 6 km southeast of Port Augusta. The Flinders Ranges Way extends 209 km to Blinman. Route B83 follows the Flinders Ranges Way through Quorn to Hawker, but then branches onto The Outback Highway along the western side of the ranges through Leigh Creek to Lyndhurst.
Copper Coast Highway is a highway in South Australia which branches off from the Augusta and Port Wakefield Highways 2 km north of Port Wakefield, and heads northwest across the top of Yorke Peninsula to Kadina, ending at the Spencer Gulf town of Wallaroo.
Wilkins Highway is an east–west route across the Yorke and Mid North region of South Australia. It runs from Augusta Highway south of Port Pirie east to Barrier Highway at the town of Hallett, near where Sir Hubert Wilkins was born.
Yorke Highway is the main road from Adelaide to the southern parts of the Yorke Peninsula in South Australia. It runs from the northeast to the southwest of the peninsula. It branches off Copper Coast Highway after rounding the top of Gulf St Vincent, runs down the coast to Ardrossan then inland through Maitland to the Spencer Gulf coast at Hardwicke Bay then through Warooka to the south coast at Marion Bay and Stenhouse Bay on Investigator Strait.
St Vincent Highway is a major road on the southern part of Yorke Peninsula in South Australia. It diverges from Yorke Highway to continue south along the coast of Gulf St Vincent near Pine Point. It passes inland of Port Vincent, Stansbury, Wool Bay and Port Giles then passes through Coobowie and Edithburgh. From here, the St Vincent Highway turns northwest to Yorketown and west to Warooka where it rejoins Yorke Highway.
Birdseye Highway is an east–west road across Eyre Peninsula in South Australia. It was named for Sylvia Birdseye who drove the first bus service to the area from Adelaide for 43 years, starting in 1928, and is the first highway in South Australia to be named for a woman.
Browns Well Highway is a road connecting Loxton, South Australia through the Murray Mallee to Pinnaroo in South Australia. It was named in 2008 after the Browns Well district for areas traversed by the highway.
Ngarkat Highway is a road in the southeastern part of South Australia, connecting Pinnaroo and Bordertown. It is designated as part of route B57 which continues north from Pinnaroo along Browns Well Highway to Loxton, and south from Bordertown along Naracoorte Road to Naracoorte.
Playford Highway is a main road on Kangaroo Island in South Australia, with its eastern end designated part of route B23. It extends from Kingscote through Cygnet River and Parndana to Cape Borda.
The Outback Highway is the road from Hawker along the western side of the Flinders Ranges through Leigh Creek to Marree. It is designated as part of route B83 from Hawker to Lyndhurst. Route B83 continues south from Hawker along the Flinders Ranges Way.
Cameron Highway is an arterial road in South Australia, connecting Alawoona on the Karoonda Highway to Paruna on the Browns Well Highway. It follows part of the former Barmera railway line.
B89 (1998–present)
Augusta Highway 
Copper Coast Highway 
Yorke Highway 
