The gateway drug effect is a comprehensive catchphrase for the often observed effect that the use of a psychoactive substance is coupled to an increased probability of the use of further substances. Possible reasons for the connection include environmental influence, impulsive people seeking both soft and hard drugs, alterations in the brain due to earlier substance exposure, as well as similar attitudes of people who use different substances, and therefore experience a "common liability to addiction". In 2020, the National Institute on Drug Abuse released a research report which supported allegations that marijuana is a "gateway" to more dangerous substance use; one of the peer-reviewed papers cited in the report claims that while "some studies have found that use of legal drugs or cannabis are not a requirement for the progression to other illicit drugs [...] most studies have supported the "gateway sequence"." However, a 2018 literature review conducted by the National Institute of Justice, which analyzed 23 peer-reviewed research studies, concluded "that existing statistical research and analysis relevant to the "gateway" hypothesis has produced mixed results", and that "no causal link between cannabis use and the use of other illicit drugs can be claimed at this time."
Cannabis, also known as marijuana or weed among other names, is a non-chemically uniform drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used by smoking, vaporizing, within food, or as an extract.
Lester Grinspoon was an American psychiatrist and long-standing associate professor of psychiatry at Harvard Medical School best known for his groundbreaking works on the science and social policy of cannabis, psychedelics and other drugs, and for his commitment to changing harmful drug policies. He concurrently served as a senior psychiatrist at the Massachusetts Mental Health Center in Boston, Massachusetts, for 40 years. Grinspoon was a fellow of the American Association for the Advancement of Science and the American Psychiatric Association. He was founding editor of The American Psychiatric Association Annual Review and Harvard Mental Health Letter. Grinspoon was editor of Harvard Mental Health Letter for fifteen years.
In the United States, the non-medical use of cannabis is legalized in 24 states and decriminalized in 7 states, as of November 2023. Decriminalization refers to a policy of reduced penalties for cannabis offenses, typically involving a civil penalty for possessing small amounts, instead of criminal prosecution or the threat of arrest. In jurisdictions without penalty the policy is referred to as legalization, although the term decriminalization is sometimes used for this purpose as well.
In the United States, increased restrictions and labeling of cannabis as a poison began in many states from 1906 onward, and outright prohibitions began in the 1920s. By the mid-1930s cannabis was regulated as a drug in every state, including 35 states that adopted the Uniform State Narcotic Drug Act. The first national regulation was the Marihuana Tax Act of 1937.
Drug liberalization is a drug policy process of decriminalizing, legalizing, or repealing laws that prohibit the production, possession, sale, or use of prohibited drugs. Variations of drug liberalization include drug legalization, drug relegalization, and drug decriminalization. Proponents of drug liberalization may favor a regulatory regime for the production, marketing, and distribution of some or all currently illegal drugs in a manner analogous to that for alcohol, caffeine and tobacco.
The use of cannabis in New Zealand is regulated by the Misuse of Drugs Act 1975, which makes unauthorised possession of any amount of cannabis a crime. Cannabis is the fourth-most widely used recreational drug in New Zealand, after caffeine, alcohol and tobacco, and the most widely used illicit drug. In 2001 a household survey revealed that 13.4% of New Zealanders aged 15–64 used cannabis. This ranked as the ninth-highest cannabis consumption level in the world.
The use, sale, and possession of cannabis containing over 0.3% THC by dry weight in the United States, despite laws in many states permitting it under various circumstances, is illegal under federal law. As a Schedule I drug under the federal Controlled Substances Act (CSA) of 1970, cannabis containing over 0.3% THC by dry weight is considered to have "no accepted medical use" and a high potential for abuse and physical or psychological dependence. Cannabis use is illegal for any reason, with the exception of FDA-approved research programs. However, individual states have enacted legislation permitting exemptions for various uses, including medical, industrial, and recreational use.
In the United States, cannabis is legal in 38 of 50 states for medical use and 24 states for recreational use. At the federal level, cannabis is classified as a Schedule I drug under the Controlled Substances Act, determined to have a high potential for abuse and no accepted medical use, prohibiting its use for any purpose. Despite this prohibition, federal law is generally not enforced against the possession, cultivation, or intrastate distribution of cannabis in states where such activity has been legalized. On May 1, 2024, the Associated Press reported on plans by the Drug Enforcement Administration to move marijuana to the less-restrictive Schedule III.
The legal history of cannabis in the United States began with state-level prohibition in the early 20th century, with the first major federal limitations occurring in 1937. Starting with Oregon in 1973, individual states began to liberalize cannabis laws through decriminalization. In 1996, California became the first state to legalize medical cannabis, sparking a trend that spread to a majority of states by 2016. In 2012, Washington and Colorado became the first states to legalize cannabis for recreational use.
Cannabis in Madagascar is illegal, but is produced and consumed domestically.
Cannabis in Latvia is illegal for recreational and medical purposes, but production of industrial hemp is permitted.
White Widow is a balanced hybrid strain of Cannabis indica and Cannabis sativa that was created and developed by Shantibaba whilst he worked at the Greenhouse Seed Company.
Cannabis in Liechtenstein is illegal with severe penalties for the production, sale, and possession of marijuana for medicinal or recreational purposes.
Cannabis in Monaco is illegal. The production, sale, and possession of marijuana for medicinal or recreational purposes being a criminal offense with a penalty of up to one year in jail in addition to a fine of up to €1680. Despite the strong laws, the police and courts are often lenient, letting offenders off with a warning.
Cannabis in Djibouti is illegal with penalties for the production, sale, and possession of marijuana for medicinal or recreational purposes. Offenders may be fined or receive up to five years in prison. Use of cannabis in Djibouti is low due to poor conditions for cultivation and the local preference for the legal drug khat.
Cannabis in Tajikistan is illegal with severe penalties for the production, sale, and possession of marijuana for medicinal or recreational purposes. Punishments include up to five years in prison for possession and capital punishment or 25-year sentence for sale.
Cannabis in Haiti is illegal with severe punishments for the production, sale, and possession of marijuana for medicinal or recreational purposes.
Cannabis in Kiribati is illegal with severe punishments for the production, sale, and possession of marijuana for medicinal or recreational purposes. A 2011 survey of young people, found that 6.8% of males and 1.6% of females had ever used cannabis.
Cannabis in Tuvalu is illegal with severe punishments for the production, sale, and possession of marijuana for medicinal or recreational purposes. Due to the nation's high development index, illegal substance abuse effectively does not exist in Tuvalu and there were no reports of drug-related crimes on Tuvalu in 2019 or 2020.
