A vaporizer or vaporiser, colloquially known as a vape, is a device used to vaporize substances for inhalation. Plant substances can be used, commonly cannabis, tobacco, or other herbs or blends of essential oil. [1] However, they are most commonly filled with a combination propylene glycol, glycerin, and drugs such as nicotine (e.g. extract from tobacco) or tetrahydrocannabinol as a liquid solution. [2]
Vaporizers contain various forms of extraction chambers including straight bore, venturi, or sequential venturi, and are made of materials such as metal or glass. The extracted vapor may be collected in an inflatable bag, or inhaled directly through a hose or pipe. When used properly, cooler temperatures due to lack of combustion [3] result in significantly more efficient extraction of the ingredients. Hence, the irritating and harmful effects of smoking are heavily reduced, [4] [5] [6] [7] [8] as is its secondhand smoke.
Cannabis flower is commonly consumed using a dry herb vaporizer. The cannabis may be heated in a chamber via indirect flame exposure or an electrical heating element, allowing users to inhale the resulting vapor. The temperatures reached are cooler than the combustion temperature of cannabis, which is around 230–315 °C (445–600 °F). [9]
Vaporizing is more efficient than smoking, because approximately 30% of THC in cannabis or hashish cigarettes is destroyed by pyrolysis during smoking. [10]
Cannabis is also consumed via the vaporization of cannabis concentrates or oils that have been extracted from the plant, commonly referred to as "dabbing". Users typically employ a torch to heat a small cup shaped quartz or titanium attachment on a bong before dabbing the oil onto the heated surface and inhaling the vapors through the bong. [11] This route of consumption is generally much more potent than smoking or vaporizing marijuana flower due to the increased concentration of cannabinoids. Users typically report that the effects of dabbing are much more intense than regular cannabis, while also being shorter lived. [12]
Cannabis concentrate is also commonly used in e-cigarette style vaporizer pens in the form of liquid containers known as cartridges. A battery connected to the atomizer is used to heat the cannabis oil, creating a vapor that is inhaled by the user. Cartridges typically contain different preparations of cannabis oil mixed with cannabinoids, terpenes, solvents (primarily Propylene glycol and Glycerol) used for thinning, fatty acids, and flavonoids. Natural or artificial terpenes are frequently added by manufacturers to enhance flavor, often using blends that mimic popular cannabis strains or sugary foods such as candy or pastries. [13]
Of the studies that have investigated cannabis vaporization, few have addressed the quality of the vapor extracted and delivered; instead, studies usually focus on the mode of usage of the vaporizers. However, those that have addressed vapor quality have demonstrated promising results. Such studies suggest that the absence of combustion results in an aerosol that contains significantly lower amounts of harmful substances found in smoke, such as tar, carbon monoxide, and carcinogenic compounds known as polynuclear aromatic hydrocarbons (PAH). [14] [9] [15] One study found that cannabis smoke contains 111 compounds (including several carcinogenic PAHs) in addition to the cannabinoids, whereas only 3 additional compounds were identified in cannabis vapor, other than the cannabinoids. [9] This suggests that the vaporization of cannabis may be a safer alternative to combusted cannabis. [16] On the other hand, a study in the UK (where cannabis is illegal) found that some illicitly distributed cannabis vaporizers contained harmful levels of xylazine, an animal sedative which can lead to overdose. [17]
An electronic cigarette is a handheld battery-powered vaporizer that simulates smoking by providing some of the behavioral aspects of smoking, including the hand-to-mouth action of smoking, but without combusting tobacco. [18] Using an e-cigarette is known as "vaping" and the user is referred to as a "vaper." [19] Instead of cigarette smoke, the user inhales an aerosol, commonly called vapor. [20] E-cigarettes typically have a heating element that atomizes a liquid solution called e-liquid. [21] E-cigarettes may be automatically activated by taking a puff; [22] others turn on manually by pressing a button. [19] Some e-cigarettes look like traditional cigarettes, [23] but they come in many variations. [19] Most versions are reusable, though some are disposable. [24] There are first-generation, [25] second-generation, [26] third-generation, [27] and fourth-generation devices. [28] E-liquids usually contain propylene glycol, glycerin, nicotine, flavorings, additives, and differing amounts of contaminants. [29] E-liquids are also sold without propylene glycol, [30] nicotine, [31] or flavors. [32]
The benefits and the health risks of e-cigarettes are uncertain. [33] [34] [35] There is tentative evidence they may help people quit smoking, [36] although they have not been proven to be more effective than smoking cessation medicine. [37] There is concern with the possibility that non-smokers and children may start nicotine use with e-cigarettes at a rate higher than anticipated than if they were never created. [38] Following the possibility of nicotine addiction from e-cigarette use, there is concern children may start smoking cigarettes. [38] Youth who use e-cigarettes are more likely to go on to smoke cigarettes. [39] [40] Their part in tobacco harm reduction is unclear, [41] while another review found they appear to have the potential to lower tobacco-related death and disease. [42] Regulated US Food and Drug Administration nicotine replacement products may be safer than e-cigarettes, [41] but e-cigarettes are generally seen as safer than combusted tobacco products. [43] [44] It is estimated their safety risk to users is similar to that of smokeless tobacco. [45] The long-term effects of e-cigarette use are unknown. [46] [47] [48] The risk from serious adverse events was reported in 2016 to be low. [49] Less serious adverse effects include abdominal pain, headache, blurry vision, [50] throat and mouth irritation, vomiting, nausea, and coughing. [51] Nicotine itself is associated with some health harms. [52] In 2019 and 2020, an outbreak of severe lung illness throughout the US has been linked to the use of contaminated black market THC vape cartridges. [53]
Vaporizers can be used to inhale other recreational drugs as well. A wide variety can be consumed this way, either dissolved in e-liquid or vaporized directly. [54] The use of e-cigarettes to inhale the psychedelic drug DMT has been reported. [55]
Studies have shown that vaporizing cannabis exposes the user to lower levels of harmful substances than smoking cannabis. [9] [56] [57] [58] These findings are important for it is estimated that 10–20% of patients with chronic pain, multiple sclerosis, epilepsy, and HIV/AIDS have admitted to smoking cannabis for therapeutic purposes. For patients, a study found that smoking cannabis sativa reduced daily pain by 34%, a statistically significant amount. [59]
In a study published in the Journal of Psychopharmacology in May 2008, it was stated that vaporizers were a "suitable method for the administration of THC". [60] A 2007 study by the University of California, San Francisco, published in the Journal of the American Academy of Neurology, found that "there was virtually no exposure to harmful combustion products using the vaporizing device". [7] A 2006 study performed by researchers at Leiden University found that vaporizers were "safe and effective cannabinoid delivery system(s)". The study stated that the amount of THC delivered by vaporizers were equivalent to the amount delivered by smoking. [58] Because of those studies and other studies, vaporizers are considered medically sound devices for delivering THC. [14]
The proposed factors affecting output include: [9] [58]
Not all those have been scientifically tested. Research using vaporizers found the delivery efficiency highest at around 226 °C (439 °F), falling to about half efficiency at 150 to 180 °C (302 to 356 °F) depending on material. [58] The purest preparations produced the highest efficiencies, about 56% for pure THC versus 29% for plant material (female flower tops) with 12% THCA content. Besides THC, several other cannabinoids as well as a range of other plant components including terpenoids were detected in the plant material. Using pure THC in the vaporizer, no degradation products (delta-8-THC (D8-THC), cannabinol (CBN), or unknown compounds) were detected by HPLC analysis. [58] The longer vapor is stored, the more THC is lost as it condenses on the surface of the vaporizer or the balloon. This loss may be negligible over a few minutes but may exceed 50% after 90 minutes. [58] The Leiden University study found that as much as 30–40% of inhaled THC was not absorbed by the lungs but simply exhaled. However, they did not find large individual differences in the amounts exhaled. [58]
Vaporizers are sometimes used by chefs as a method of applying controlled heat to herbs and spices to release flavors that are otherwise difficult to titrate or apply, or that might be spoiled by overheating during cooking. [61] [62] [63] Grant Achatz, chef-proprietor of Alinea in Chicago, "uses the aroma-filled bags as place-mats, punctured when plates are placed in front of the customer". [61]
A cigarette is a narrow cylinder containing a combustible material, typically tobacco, that is rolled into thin paper for smoking. The cigarette is ignited at one end, causing it to smolder; the resulting smoke is orally inhaled via the opposite end. Cigarette smoking is the most common method of tobacco consumption. The term cigarette, as commonly used, refers to a tobacco cigarette, but the word is sometimes used to refer to other substances, such as a cannabis cigarette or a herbal cigarette. A cigarette is distinguished from a cigar by its usually smaller size, use of processed leaf, different smoking method, and paper wrapping, which is typically white.
Cannabis smoking is the inhalation of smoke or vapor released by heating the flowers, leaves, or extracts of cannabis and releasing the main psychoactive chemical, Δ9-tetrahydrocannabinol (THC), which is absorbed into the bloodstream via the lungs. Archaeological evidence indicates cannabis with high levels of THC was being smoked at least 2,500 years ago. As of 2021, cannabis is the most commonly consumed federally illegal drug in the United States, with 36.4 million people consuming it monthly.
An electronic cigarette (e-cigarette) or vape is a device that simulates tobacco smoking. It consists of an atomizer, a power source such as a battery, and a container such as a cartridge or tank. Instead of smoke, the user inhales vapor. As such, using an e-cigarette is often called "vaping". The atomizer is a heating element that vaporizes a liquid solution called e-liquid, which quickly cools into an aerosol of tiny droplets, vapor and air. The vapor mainly comprises propylene glycol and/or glycerin, usually with nicotine and flavoring. Its exact composition varies, and depends on several things including user behavior.
Cannabis consumption refers to the variety of ways cannabis is consumed, among which inhalation and ingestion are most common. All consumption methods involve heating the plant's THCA to decarboxylate it into THC, either at the time of consumption or during preparation. Salves and absorption through the skin (transdermal) are increasingly common in medical uses, both of CBD, THC, and other cannabinoids. Each method leads to subtly different psychoactive effects due to the THC and other chemicals being activated, and then consumed through different administration routes. It is generally considered that smoking, which includes combustion toxins, comes on quickly but lasts for a short period of time, while eating delays the onset of effect but the duration of effect is typically longer. In a 2007 ScienceDaily report of research conducted at the University of California–San Francisco, researchers reported that vaporizer users experience the same biological effect, but without the toxins associated with smoking. Δ9-THC is the primary component when inhaled, but when eaten the liver converts this to the more psychoactive 11-hydroxy-THC form.
Hash oil or cannabis oil is an oleoresin obtained by the extraction of cannabis or hashish. It is a cannabis concentrate containing many of its resins and terpenes – in particular, tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids. Hash oil is usually consumed by smoking, vaporizing or eating. Preparations of hash oil may be solid or semi-liquid colloids depending on both production method and temperature and are usually identified by their appearance or characteristics. Color most commonly ranges from transparent golden or light brown, to tan or black. There are various extraction methods, most involving a solvent, such as butane or ethanol.
Blu is an electronic cigarette brand, produced by Fontem Ventures and owned by Imperial Brands. The brand Blu sells various types of rechargeable and disposable e-cigarettes with a wide selection of flavored and unflavored liquids. Its products are available in many countries and each market offers different types of products suited to public demand and opportunities. The global headquarters of Blu is located in Amsterdam. Local offices are active around the world to service all markets which sell the brand.
The health effects of electronic cigarettes (e-cigarettes) include a range of potential risks such as exposure to toxic chemicals, the possibility of increased likelihood of respiratory and cardiovascular diseases, and concerns about their possible role in cancer development. Upon their introduction, there were marketing claims that they were a safer alternative to traditional tobacco products.
The scientific community in the United States and Europe are primarily concerned with the possible effect of electronic cigarette use on public health. There is concern among public health experts that e-cigarettes could renormalize smoking, weaken measures to control tobacco, and serve as a gateway for smoking among youth. The public health community is divided over whether to support e-cigarettes, because their safety and efficacy for quitting smoking is unclear. Many in the public health community acknowledge the potential for their quitting smoking and decreasing harm benefits, but there remains a concern over their long-term safety and potential for a new era of users to get addicted to nicotine and then tobacco. There is concern among tobacco control academics and advocates that prevalent universal vaping "will bring its own distinct but as yet unknown health risks in the same way tobacco smoking did, as a result of chronic exposure", among other things.
Cloud-chasing is the activity of blowing large clouds of vapor using an electronic cigarette. Using the devices for "cloud-chasing" began in the West Coast of the US. The exact origins of the activity are unclear, but most competitive e-cigarette users say that it started around 2012. Competitive vaping is increasing in popularity internationally, spreading from the US and Canada to Indonesia. Cloud-chasing is a recreational activity and a hobby.
An electronic cigarette is a handheld battery-powered vaporizer that simulates smoking, but without tobacco combustion. E-cigarette components include a mouthpiece, a cartridge, a heating element/atomizer, a microprocessor, a battery, and some of them have an LED light on the end. An atomizer consists of a small heating element, or coil, that vaporizes e-liquid and a wicking material that draws liquid onto the coil. When the user inhales a flow sensor activates the heating element that atomizes the liquid solution; most devices are manually activated by a push-button. The e-liquid reaches a temperature of roughly 100–250 °C (212–482 °F) within a chamber to create an aerosolized vapor. The user inhales an aerosol, which is commonly but inaccurately called vapor, rather than cigarette smoke. Vaping is different from smoking, but there are some similarities, including the hand-to-mouth action of smoking and an aerosol that looks like cigarette smoke. The aerosol provides a flavor and feel similar to tobacco smoking. There is a learning curve to use e-cigarettes properly. E-cigarettes are cigarette-shaped, and there are many other variations. E-cigarettes that resemble pens or USB memory sticks are also sold that may be used unobtrusively.
The chemical composition of the electronic cigarette aerosol varies across and within manufacturers. Limited data exists regarding their chemistry. However, researchers at Johns Hopkins University analyzed the vape clouds of popular brands such as Juul and Vuse, and found "nearly 2,000 chemicals, the vast majority of which are unidentified."
A vape shop is a retail outlet specializing in the selling of vaping products, though shops selling derived psychoactive cannabis products have increased in the United States since the passage of the 2018 Farm Bill. There are also online vape shops. A vape shop offers a range of vaping products. The majority of vape shops do not sell vaping products that are from "Big Tobacco" companies. In 2013, online search engine searches on vape shops surpassed searches on e-cigarettes. Around a third of all sales of vaping products in one US state took place in vape shops. Big Tobacco believes the independent vape market is a threat to their interests.
A heated tobacco product (HTP) is a tobacco product that heats the tobacco at a lower temperature than conventional cigarettes. These products contain nicotine, which is a highly addictive chemical. The heat generates an aerosol or smoke to be inhaled from the tobacco, which contains nicotine and other chemicals. HTPs may also contain additives not found in tobacco, including flavoring chemicals. HTPs generally heat tobacco to temperatures under 600 °C (1100 °F), a lower temperature than conventional cigarettes.
Pod mods are a type of electronic cigarette used to vape nicotine through a mouthpiece connected to the body of the device by magnets. These devices are a newer generation of e-cigarettes that are often marketed to a younger crowd that do not wish to attract attention gained through regular e-cigarettes or traditional tobacco-burning cigarettes. Pod mods contain a disposable cartridge and coils.
Exposure to nicotine, from conventional or electronic cigarettes during adolescence can impair the developing human brain. E-cigarette use is recognized as a substantial threat to adolescent behavioral health. The use of tobacco products, no matter what type, is almost always started and established during adolescence when the developing brain is most vulnerable to nicotine addiction. Young people's brains build synapses faster than adult brains. Because addiction is a form of learning, adolescents can get addicted more easily than adults. The nicotine in e-cigarettes can also prime the adolescent brain for addiction to other drugs such as cocaine. Exposure to nicotine and its great risk of developing an addiction, are areas of significant concern.
An outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI) started in 2019 among users of illegal, unregulated cannabis vaping products, almost exclusively in the United States. The first cases of this particular outbreak were identified in Illinois and Wisconsin in April 2019; as of 18 February 2020, a total of 2,807 hospitalized cases, including 68 deaths, have been confirmed. According to the U.S. Centers for Disease Control (CDC), "Vitamin E acetate is strongly linked to the EVALI outbreak...Evidence is not sufficient to rule out the contribution of other chemicals of concern, including chemicals in either THC or non-THC products, in some of the reported EVALI cases".
Vaping-associated pulmonary injury (VAPI), also known as vaping-associated lung injury (VALI) or e-cigarette, or vaping, product use associated lung injury (E/VALI), is an umbrella term, used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. Symptoms can initially mimic common pulmonary diagnoses, such as pneumonia, but sufferers typically do not respond to antibiotic therapy. Differential diagnoses have overlapping features with VAPI, including COVID-19. According to a systematic review article, "Initial case reports of vaping-related lung injury date back to 2012, but the ongoing outbreak of EVALI began in the summer of 2019." According to an article in the Radiological Society of North America news published in March 2022, EVALI cases continue to be diagnosed. “EVALI has by no means disappeared,” Dr. Kligerman said. “We continue to see numerous cases, even during the pandemic, many of which are initially misdiagnosed as COVID-19.”
Electronic cigarettes are marketed to smoking and non-smoking men, women, and children as being safer than cigarettes. In the 2010s, large tobacco businesses accelerated their marketing spending on vape products, similar to the strategies traditional cigarette companies used in the 1950s and 1960s.
Nicotine salts are salts formed from nicotine and an acid. They are found naturally in tobacco leaves. Various acids can be used, leading to different conjugate bases paired with the ammonium form of nicotine.