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Cannabis strains is a popular name to refer to plant varieties of the monospecific genus Cannabis sativa L.. They are either pure or hybrid varieties of the plant, which encompasses various sub-species C. sativa , C. indica , and C. ruderalis .
Varieties are developed to intensify specific characteristics of the plant, or to differentiate the strain for the purposes of marketing or to make it more effective as a drug. Variety names are typically chosen by their growers, and often reflect properties of the plant such as taste, color, smell, or the origin of the variety. [2] The Cannabis strains referred to in this article are primarily those varieties with recreational and medicinal use. These varieties have been cultivated to contain a high percentage of cannabinoids. Several varieties of cannabis, known as hemp, have a very low cannabinoid content, and are instead grown for their fiber and seed. Due to the legal status of the plant in many jurisdictions, Cannabis plant varieties are at high risk of biopiracy. [3] [4]
The two species of the Cannabis genus that are most commonly grown are Cannabis indica and Cannabis sativa . [5] A third species, Cannabis ruderalis , is very short and produces only trace amounts of tetrahydrocannabinol (THC), and thus is not commonly grown for industrial, recreational or medicinal use. However, because Cannabis ruderalis flowers independently of the photoperiod and according to age, it has been used to breed autoflowering strains. [6]
Pure sativas are relatively tall (reaching as high as 4.5 meters), with long internodes and branches, and large, narrow-bladed leaves. Pure indica varieties are shorter and bushier, with wider leaflets. They are often favored by indoor growers for their size. Sativas bloom later than indicas, often taking a month or two longer to mature. The subjective effects of sativas and indicas are said to differ, but the ratio of tetrahydrocannabinol (THC) to cannabidiol (CBD) in most named drug varieties of both types is similar (averaging about 200:1). Unlike most commercially developed strains, indica landraces exhibit plants with varying THC/CBD ratios. [7] Avidekel, a medical marijuana strain developed in Israel, has a very low content of THC but a high content of CBD, limiting its psychoactive potential while exploring the beneficial medical effects of the latter. [8]
The informal designation sativa and indica may have various, controversial meanings. Morphologically, the name sativa designates tall plants with narrow leaves, while indica refers to short plants with wide leaves. Among the marijuana community however, sativa rather refers to equatorial varieties producing stimulating psychoactive effects, whereas indica-type plants from Central Asia are used for relaxing and sedative drugs (THC:CBD > 1). [9]
There is an increasing discussion about whether the differences between species adequately represents the variability found within the genus Cannabis. [10] [11] [12] [13]
There are five chemotaxonomic types of cannabis: one with high levels of THC, one which is more fibrous and has higher levels of CBD, one that is an intermediate between the two, another one with high levels of cannabigerol (CBG), and the last one almost without cannabinoids. [14]
There has also been a recent movement [15] to characterize strains based on their reported subjective effects. For example, WoahStork has used machine learning algorithms to classify strains into six Distinct Activity groups. [16]
Plant breeding is subject to a different set of rules and regulations, at times contradictory. The International Union for the Protection of New Varieties of Plants (UPOV Convention) grants limited proprietary rights to breeders over their seeds, under certain conditions. In parallel, and often in a conflicting way, a series of dispositions aiming to fight against biopiracy require breeders to prove that the free, prior and informed consent was obtained from the communities (often Indigenous peoples or peasant communities) from where the seeds used to breed the new variety originates. [3] This is the case in particular of the Nagoya Protocol, a treaty complementing the Convention on Biological Diversity, in force since 2014 (2017 in the European Union). [17]
In 2024, the GRATK Treaty was adopted, [18] preventing national patent offices from granting patents based on biopiracy. [19] Patent applicants relying on Cannabis strains will have to disclose the origin of the variety, which often entails compliance under the Nagoya protocol or other similar mechanisms of Access and Benefit Sharing Agreement. [20]
In addition to pure indica, sativa, and ruderalis varieties, hybrid varieties with varying ratios of these three types are common, such as the White Widow hybrid which has about 60% indica and 40% sativa ancestry. These hybrid varieties exhibit traits from both parental types. There are also commercial crossbred hybrids which contain a mix of both ruderalis, indica or sativa genes, and are usually autoflowering varieties. These varieties are bred mostly for the medicinal cannabis market, since they are not very appreciated by recreational cannabis users because ruderalis varieties are lower in THC and impart a slightly unpleasant taste. "Lowryder" was an early auto-flowering hybrid that retained the flowering behavior of ruderalis plants, while also producing appreciable amounts of THC and CBD. Autoflowering cannabis varieties have the advantage of being discreet due to their small stature. They also require shorter growing periods, as well as having the additional advantage that they do not rely on a change in the photoperiod to determine when to flower.
Breeding requires pollinating a female cannabis plant with male pollen. Although this occurs spontaneously and ubiquitously in nature, the intentional creation of new varieties typically involves selective breeding in a controlled environment.
When cannabis is cultivated for its psychoactive or medicinal properties, male plants will often be separated from females. This prevents fertilization of the female plants, either to facilitate sin semilla flowering or to provide more control over which male is chosen. Pollen produced by the male is caught and stored until it is needed.
When a male plant of one strain pollinates a female of another strain, the seeds will be F1 hybrids of the male and female. These offspring will not be identical to their parents. Instead, they will have characteristics of both parents. Repeated breeding results in certain characteristics appearing with greater regularity.
It is impossible for a hermaphrodite to create any male-only seeds. A hermaphrodite may create female only seeds and hermaphrodite seeds. Also the female-only seeds may carry the hermaphrodite trait. [21]
Hybridization is the process of plants and animals breeding. Natural wind currents help speed up this hybridization process and promotes a positive growth. Some plants produce many seeds while some produce little to none depending on how it is bred. If seeds are produced traits from both the original parents will be expressed.
Techniques such as mutation breeding are used to develop new strains using irradiation or chemical mutagens such as colchicine. [22] Various companies have been experimenting with creating new strains using genetic engineering techniques. [23] [24] [25]
During the selective breeding process for medical marijuana, THC:CBD ratios are accounted for and accommodated to the needs of the client's preference/illness. Due to the large genetic diversity and different geographical climates and environments, a wide range of strains and properties exist.
THC is associated with the psychoactive high, while CBD is not psychoactive and is purported to have medicinal properties. [26] [27] [28]
There is little evidence about the safety or efficacy of cannabinoids in the treatment of epilepsy. [29] [30]
In order for there to be genetic stability within a marijuana strain the breeder has to go through selection and breeding, pinpointing the dominant and recessive genes within the two strains being crossed. After analyzing offspring with the preferred traits a breeder is looking for, the breeder will select the preferred traits and continue to breed those offspring to create the desired final product. Selection is a crucial process for a breeder to create a strain, especially if a client is looking for something with specific plant traits the breeder has to ensure that the hybrid's genetic traits have been closed in enough so unwanted traits aren't expressed in future harvests.
In a retail market that is decriminalized such as in The Netherlands, where wholesale production is illegal but prosecutions are not always enforced because of the contradiction of the law that is recognised by the courts, [31] competition puts pressure on breeders to create increasingly attractive varieties to maintain market share. Breeders give their strains distinct and memorable names in order to help differentiate them from their competitors' strains, although they may in fact be very similar.
Acapulco Gold is a golden-leafed Cannabis sativa strain originally from the Acapulco area of southwest Mexico. [32] [33] [34]
Bedrocan is a medicinal cannabis variety cultivated from a Dutch medical marijuana Cannabis sativa L. strain, having a standardized content of THC (22%) and CBD (1%). It is currently cultivated by Bedrocan Nederland, Bedrocan Canada and Bedrocan Česká Republika. It was introduced in 2003 and is dispensed through pharmacies after prescription from a physician. [35]
Blue Dream is a hybrid cannabis strain widely used for both medical and recreational purposes, developed in 2003. [36]
Charlotte's Web is a high-cannabidiol (CBD), low-tetrahydrocannabinol (THC) cannabis variety and extract marketed as a dietary supplement under federal law of the United States. [37] [38] [39] It is produced by the Stanley brothers in Colorado. It does not induce the psychoactive "high" typically associated with recreational marijuana strains that are high in THC. [40] In September 2014, the Stanleys announced that they would ensure that the product consistently contained less than 0.3% THC. [41] Charlotte's Web gained national attention when it was used to treat Charlotte Figi's epileptic seizures. [42] [43] Her story has led to her being described as "the girl who is changing medical marijuana laws across America," [44] as well as the "most famous example of medicinal hemp use". [45]
Skunk refers to cannabis strains that are strong-smelling and have been likened to the smell of the spray from a skunk. These strains of cannabis are believed to have originated during the early 1990s in the United States prior to larger-scale development and popularization by Dutch growers. [46] Just as with other strains of cannabis, skunk is commonly grown in controlled indoor environments under specialized grow lights, or in a greenhouse when full outdoor conditions are not suitable; skunk strains are hybrids of Cannabis sativa and Cannabis indica. [46]
Sour Diesel is a hybrid strain of Cannabis sativa and Cannabis indica.
Cannabis is a genus of flowering plants in the family Cannabaceae. The number of species within the genus is disputed. Three species may be recognized: Cannabis sativa, C. indica, and C. ruderalis. Alternatively, C. ruderalis may be included within C. sativa, all three may be treated as subspecies of C. sativa, or C. sativa may be accepted as a single undivided species. The genus is widely accepted as being indigenous to and originating from Asia.
Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Its chemical formula C21H30O2 includes compounds, the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ9-tetrahydrocannabinol. It is a colorless oil.
Medical cannabis, medicinal cannabis or medical marijuana (MMJ), is cannabis and cannabinoids that are prescribed by physicians for their patients. The use of cannabis as medicine has not been rigorously tested due to production and governmental restrictions, resulting in limited clinical research to define the safety and efficacy of using cannabis to treat diseases.
Cannabinoids are several structural classes of compounds found in the cannabis plant primarily and most animal organisms or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (delta-9-THC), the primary psychoactive compound in cannabis. Cannabidiol (CBD) is also a major constituent of temperate cannabis plants and a minor constituent in tropical varieties. At least 113 distinct phytocannabinoids have been isolated from cannabis, although only four have been demonstrated to have a biogenetic origin. It was reported in 2020 that phytocannabinoids can be found in other plants such as rhododendron, licorice and liverwort, and earlier in Echinacea.
Cannabis sativa is an annual herbaceous flowering plant. The species was first classified by Carl Linnaeus in 1753. The specific epithet sativa means 'cultivated'. Indigenous to Eastern Asia, the plant is now of cosmopolitan distribution due to widespread cultivation. It has been cultivated throughout recorded history and used as a source of industrial fiber, seed oil, food, and medicine. It is also used as a recreational drug and for religious and spiritual purposes.
Cannabinol (CBN) is a mildly psychoactive cannabinoid that acts as a low affinity partial agonist at both CB1 and CB2 receptors. This activity at CB1 and CB2 receptors constitutes interaction of CBN with the endocannabinoid system (ECS).
Cannabidiol (CBD) is a phytocannabinoid discovered in 1940. It is one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. As of 2022, clinical research on CBD included studies related to the treatment of anxiety, addiction, psychosis, movement disorders, and pain, but there is insufficient high-quality evidence that cannabidiol is effective for these conditions. CBD is also sold as a herbal dietary supplement promoted with unproven claims of particular therapeutic effects.
Cannabis, also known as marijuana or weed, among other names, is a non-chemically uniform drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used by smoking, vaporizing, within food, or as an extract.
Cultivation of cannabis is the production of cannabis infructescences. Cultivation techniques for other purposes differ.
Cannabis indica is an annual plant species in the family Cannabaceae indigenous to the Hindu Kush mountains of Southern Asia. The plant produces large amounts of tetrahydrocannabinol (THC) and tetrahydrocannabivarin (THCV), with total cannabinoid levels being as high as 53.7%. It is now widely grown in China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa, and is cultivated for purposes including hashish in India. The high concentrations of THC or THCV provide euphoric effects making it popular for use for several purposes such as recreational drugs, clinical research drugs and the potential of Cannabis or selected constituents for new drug research or being used in alternative medicine, among many others.
Cannabis ruderalis is a variety, subspecies, or species of Cannabis native to Central and Eastern Europe and Russia. It contains a relatively low quantity of psychoactive compound tetrahydrocannabinol (THC) and does not require photoperiod to blossom. Some scholars accept C. ruderalis as its own species due to its unique traits and phenotypes which distinguish it from C. indica and C. sativa; others debate whether ruderalis is a subspecies under C. sativa.
Cannabis tea is a cannabis-infused drink prepared by steeping various parts of the cannabis plant in hot or cold water. Cannabis tea is commonly recognized as an alternative form of preparation and consumption of the cannabis plant, more popularly known as marijuana, pot, or weed. This plant has long been recognized as an herbal medicine employed by health professionals worldwide to ease symptoms of disease, as well as a psychoactive drug used recreationally and in spiritual traditions. Though less commonly practiced than popular methods like smoking or consuming edibles, drinking cannabis tea can produce comparable physical and mental therapeutic effects. Such effects are largely attributed to the THC and CBD content of the tea, levels of which are drastically dependent on individual preparation techniques involving volume, amount of cannabis, and boiling time. Also in common with these administration forms of cannabis is the heating component performed before usage. Due to the rather uncommon nature of this particular practice of cannabis consumption in modern times as well as the legality of cannabis throughout the World, the research available on the composition of cannabis tea is limited and based broadly around what is known of cannabis as it exists botanically.
Autoflowering cannabis or day neutral cannabis varieties automatically switch from vegetative growth to the flowering stage based on age, as opposed to the ratio of light to dark hours required with photoperiod dependent/short-day strains. Many autoflowering varieties are ready to harvest in less than 10 weeks from seed. Dwarf varieties can have short stature while still giving decent harvests.
Charlotte's Web is a brand of high-cannabidiol (CBD), low-tetrahydrocannabinol (THC) products derived from industrial hemp and marketed as dietary supplements and cosmetics under federal law of the United States. It is produced by Charlotte's Web, Inc. in Colorado. Hemp-derived products do not induce the psychoactive "high" typically associated with recreational marijuana strains that are high in THC. Charlotte's Web hemp-derived products contain less than 0.3% THC.
The entourage effect is a hypothesis that cannabis compounds other than tetrahydrocannabinol (THC) act synergistically with it to modulate the overall psychoactive effects of the plant.
Terms related to cannabis include:
The following outline is provided as an overview of and topical guide to the plant Cannabis sativa and its relatives Cannabis indica and Cannabis ruderalis, the drug cannabis (drug) and the industrial product hemp.
Cannabinoids are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis. Cannabidiol (CBD) is another major constituent of some cannabis plants. CBD heated to 250–300 °C may partially be converted into THC.
AK-47, also known simply as AK, is a cannabis strain with high THC content. It is a hybrid strain of cannabis that is sativa-dominant; it mixes Colombian, Mexican, Thai, and Afghan strains. A strong and popular strain, it has won multiple cannabis industry awards. The plant genetics of AK-47 have been studied scientifically.
'Charlotte's Web is high in CBD and low in THC,' ... To many in the medical community, these parents are relying, at best, on shaky science. A 2013 Cochrane review of studies examining CBD as a treatment for epilepsy concluded that, due to the dearth of large, high-quality studies, 'the safety of long-term cannabidiol treatment cannot be reliably assessed.'