Crotalaria

Last updated

Crotalaria
2013.10.31.150923 Rattlepod (Crotalaria retusa) Chain of Craters Road Hawaii Volcanoes National Park Hawaii.jpg
Crotalaria retusa
Rattlepod.JPG
Rattlepod
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Fabales
Family: Fabaceae
Subfamily: Faboideae
Tribe: Crotalarieae
Genus: Crotalaria
L.
Species

See List of Crotalaria species

Synonyms
  • GoniogynaDC. 1825
  • HeylandiaDC. 1825
  • PriotropisWight & Arn. 1834
  • QuirosiaBlanco

Crotalaria is a genus of flowering plants in the family Fabaceae (subfamily Faboideae) commonly known as rattlepods. [1] The genus includes over 700 species of herbaceous plants and shrubs. Africa is the continent with the majority of Crotalaria species (approximately 400 species), which are mainly found in damp grassland, especially in floodplains, depressions and along edges of swamps and rivers, but also in deciduous bush land, roadsides and fields. Some species of Crotalaria are grown as ornamentals. The common name rattlepod or rattlebox is derived from the fact that the seeds become loose in the pod as they mature, and rattle when the pod is shaken. The name derives from the Ancient Greek κρόταλον, meaning "castanet", and is the same root as the name for the rattlesnakes ( Crotalus ).

Contents

Crotalaria species are used as food plants by the larvae of some Lepidoptera species including Endoclita sericeus , Etiella zinckenella and Utetheisa ornatrix . The toxic alkaloids produced by some members of this genus are known to be incorporated by Utetheisia larvae and used to secure their defense from predators. [2]

Current and potential uses

Food and health

Several species of Crotalaria are cultivated as crops to be consumed by human populations throughout the world. To ensure the survival and optimal cultivation of these plants, they are often selected for resistance to diseases, yield, and nutritional quality.[ citation needed ]

The wild and domesticated landraces of Crotalaria tetragona, colloquially known as "Tum-thang", are grown and eaten by the tribal communities of the Mizoram state of North-east India. The flowers and pods of Crotalaria tetragona are eaten as vegetables, the flowers and buds are used as garnishing, and the seeds are eaten as pulse. [3] In the Lake Victoria basin of East Africa, the wild and cultivated lines of Crotalaria brevidens, also known as “mitoo,” are harvested and eaten as a leafy vegetable in many popular cuisines. In Malawi it is Zumba.

Its wide consumption is mainly due to its nutritional value as a rich source of β-carotene, which is a precursor of vitamin A. [4] Crotalaria longirostrata , also known as longbeak rattlebox or chipilín, is found in Guatemala, El Salvador, and Oaxaca and is a popular addition to many local dishes. The edible portions of the plant are the leaves and shoots, which are cooked and served as a leafy green vegetable or desiccated and used as an herb. The foliage contains high amounts of calcium, iron, thiamine, riboflavin, niacin, and ascorbic acid, while the seeds and roots are considerably toxic. [5] Crotalaria longirostrata is considered a noxious weed in the United States since it is avoided as a source of consumption by many animals and since its seeds shatter and spread over a wide range.

Australian species of the genus Crotalaria have the capacity to be cultivated into potential grain crops that are adapted to dry environments, nutrient poor soils, and low-input agricultural systems. Australian Crotalaria species also show many suitable traits of harvestability, including an upright growth habit, a low tendency to dehisce and shatter, the bearing of its fruits and flowers at the ends of branches, and large to moderate seeds. [6]

Other uses

Several species of Crotalaria are currently being cultivated for suitable traits that are not directly related to human consumption. Crotalaria juncea , also known as sunn hemp, is currently grown throughout the tropics and subtropics [7] as a source of green manure, lightened fiber, and fodder. Crotalaria juncea is also being considered as a potential source of cellulosic ethanol for biofuel. [8]

Properties

Toxicity

The primary source of toxicity for many species of Crotalaria is the presence of pyrrolizidine alkaloids, which are poisonous to birds and large mammals. The two kinds of pyrrolizidine alkaloids that are found in Crotalaria plants are monocrotaline and spectabiline. Monocrotaline is most toxic to the pulmonary vasculature and is used in animal studies to induce pulmonary arterial hypertension for human modeling. Both alkaloids show clinical hepatotoxicity and carcinogenicity. They can be found in the leguminous seeds, foliage, stems, or roots of Crotalaria plants. Species with higher concentrations of pyrrolizidine alkaloids yield greater toxic effects compared to those with lower concentrations. In addition, species that contain only monocrotaline are more poisonous than species that contain only spectabiline at equal concentrations within the seeds, leaves, stems, or roots. There are no confirmed species to this date that contain both spectabiline and monocrotaline; a Crotalaria plant can only have either one or the other. Thus, plants that are less toxic and therefore more appropriate for human consumption carry only low concentrations of spectabiline. According to one study, species that display the greatest toxicity include Crotalaria spectabilis Roth,C. retusa L.,C. alata Leveille, and C. quinquefolia L. Species that are least toxic include Crotalaria australis Bak. Ex Verdoorn,C. maxillaris Klotzsch,C. sphaerocarpa, C. juncea L, and C. brevidens Benth., among many others. [9]

The toxic alkaloids are attractive to butterflies in the subfamily Danaiinae and large aggregations of butterflies occur during the flowering of Crotalaria species in Asia. These butterflies also obtain alkaloids from sap emerging from withering stems and terminal branches. [10]

Among pyrrolizidine alkaloid-containing plants, Crotalaria species cause the greatest range of tissue damage to most domesticated species, causing lung lesions in cattle, sheep, goats, horses, and pigs, and liver damage in most livestock. [1] Some species produce severe kidney lesions [1]

In March 2019, horses in the Federal District of Brazil were fed oats contaminated with Crotalaria seeds, from an earlier seeding intended to increase nitrogen levels in the soil, and at least 13 of them died of liver failure. [11]

Species

Crotalaria grahamiana in Thekkady, Kerala Crotalaria grahamiana-Thekkady-2016-12-03-001.jpg
Crotalaria grahamiana in Thekkady, Kerala
Fruits of Crotalaria pumila Crotalaria pumila (Fabaceae).jpg
Fruits of Crotalaria pumila

See also

Related Research Articles

<span class="mw-page-title-main">Bean</span> Seed of one of several genera of the plant family Fabaceae

A bean is the seed of several plants in the family Fabaceae, which are used as vegetables for human or animal food. They can be cooked in many different ways, including boiling, frying, and baking, and are used in many traditional dishes throughout the world.

<span class="mw-page-title-main">Legume</span> Plant in the family Fabaceae

A legume is a plant in the family Fabaceae, or the fruit or seed of such a plant. When used as a dry grain, the seed is also called a pulse. Legumes are grown agriculturally, primarily for human consumption, for livestock forage and silage, and as soil-enhancing green manure. Well-known legumes include beans, soybeans, chickpeas, peanuts, lentils, lupins, grass peas, mesquite, carob, tamarind, alfalfa, and clover. Legumes produce a botanically unique type of fruit – a simple dry fruit that develops from a simple carpel and usually dehisces on two sides.

<span class="mw-page-title-main">Borage</span> Species of flowering plant in the family Boraginaceae

Borage, also known as starflower, is an annual herb in the flowering plant family Boraginaceae. It is native to the Mediterranean region, and has naturalized in many other locales.

<i>Tussilago</i> Species of flowering plant in the daisy family Asteraceae

Tussilago farfara, commonly known as coltsfoot, is a plant in the tribe Senecioneae in the family Asteraceae, native to Europe and parts of western and central Asia. The name "tussilago" is derived from the Latin tussis, meaning cough, and ago, meaning to cast or to act on. It has had uses in traditional medicine, but the discovery of toxic pyrrolizidine alkaloids in the plant has resulted in liver health concerns.

<i>Crotalaria longirostrata</i> Species of flowering plant

Crotalaria longirostrata, the chipilín, is a perennial legume that is native to Mexico and Central America. Other common names include chepil, chepilin, chipilin and longbeak rattlebox.

<i>Cnidoscolus aconitifolius</i> Species of tree

Cnidoscolus aconitifolius, commonly known as chaya, tree spinach, or spinach tree, is a large, fast-growing and leafy perennial shrub that is believed to have originated in the Yucatán Peninsula of southeastern México. The specific epithet, aconitifolius, refers to the plant’s "Aconitum-like leaves"—coincidentally, another well-known dangerous, even deadly, genus of plants. As with most euphorbias, the entire plant contains a caustic, viscous and potentially dangerous white sap which flows readily when any part of the plant is broken, cut or damaged.

<i>Lupinus angustifolius</i> Species of legume

Lupinus angustifolius is a species of lupin known by many common names, including narrowleaf lupin, narrow-leaved lupin and blue lupin. It is native to Eurasia and northern Africa and naturalized in parts of Australia and North America. It has been cultivated for over 6000 years as a food crop for its edible legume seeds, as a fodder for livestock and for green manure.

<span class="mw-page-title-main">Pyrrolizidine alkaloid</span> Class of chemical compounds

Pyrrolizidine alkaloids (PAs), sometimes referred to as necine bases, are a group of naturally occurring alkaloids based on the structure of pyrrolizidine. Pyrrolizidine alkaloids are produced by plants as a defense mechanism against insect herbivores. More than 660 PAs and PA N-oxides have been identified in over 6,000 plants, and about half of them exhibit hepatotoxicity. They are found frequently in plants in the Boraginaceae, Asteraceae, Orchidaceae and Fabaceae families; less frequently in the Convolvulaceae and Poaceae, and in at least one species in the Lamiaceae. It has been estimated that 3% of the world’s flowering plants contain pyrrolizidine alkaloids. Honey can contain pyrrolizidine alkaloids, as can grains, milk, offal and eggs. To date (2011), there is no international regulation of PAs in food, unlike those for herbs and medicines.

<i>Crotalaria juncea</i> Species of legume

Crotalaria juncea, known as brown hemp, Indian hemp, Madras hemp, or sunn hemp,धाकटी घागरी, is a tropical Asian plant of the legume family (Fabaceae). It is generally considered to have originated in India.

<i>Erythrina fusca</i> Species of legume

Erythrina fusca is a species of flowering tree in the legume family, Fabaceae. It is known by many common names, including purple coraltree, gallito, bois immortelle, bucayo, and the more ambiguous "bucare" and "coral bean". E. fusca has the widest distribution of any Erythrina species; it is the only one found in both the New and Old World. It grows on coasts and along rivers in tropical Asia, Oceania, the Mascarene Islands, Madagascar, Africa, and the Neotropics.

<i>Utetheisa ornatrix</i> Species of moth

Utetheisa ornatrix, also called the ornate bella moth, ornate moth, bella moth or rattlebox moth is a moth of the subfamily Arctiinae. It is aposematically colored ranging from pink, red, orange and yellow to white coloration with black markings arranged in varying patterns on its wings. It has a wingspan of 33–46 mm. Moths reside in temperate midwestern and eastern North America as well as throughout Mexico and other parts of Central America. Unlike most moths, the bella moth is diurnal. Formerly, the bella moth or beautiful utetheisa of temperate eastern North America was separated as Utetheisa bella. Now it is united with the bella moth in Utetheisa ornatrix.

<span class="mw-page-title-main">Senecionine</span> Chemical compound

Senecionine is a toxic pyrrolizidine alkaloid isolated from various botanical sources. It takes its name from the Senecio genus and is produced by many different plants in that genus, including Jacobaea vulgaris. It has also been isolated from several other plants, including Brachyglottis repanda, Emilia, Erechtites hieraciifolius, Petasites, Syneilesis, Crotalaria, Caltha leptosepala, and Castilleja.

Pyrrolizidine alkaloidosis is a disease caused by chronic poisoning found in humans and other animals caused by ingesting poisonous plants which contain the natural chemical compounds known as pyrrolizidine alkaloids. Pyrrolizidine alkaloidosis can result in damage to the liver, kidneys, heart, brain, smooth muscles, lungs, DNA, lesions all over the body, and could be a potential cause of cancer. Pyrrolizidine alkaloidosis is known by many other names such as "Pictou Disease" in Canada and "Winton Disease" in New Zealand. Cereal crops and forage crops can sometimes become polluted with pyrrolizidine-containing seeds, resulting in the alkaloids contaminating flour and other foods, including milk from cows feeding on these plants.

<i>Erythrina edulis</i> Species of tree

Erythrina edulis (basul) is a nitrogen fixing tree that is native to the Andean region from western Venezuela to southern Bolivia. Nowadays it is known in Venezuela as "frijol mompás", in Bolivia, Peru and Northwest Argentina as "psonay", "pajuro", "sachaporoto del basul" or "poroto del sacha", in Colombia as "chachafruto", "balú", "baluy" or "sachaporoto" and in Ecuador as "guato". Although it is widely known, it is not commonly cultivated. Future research is needed, especially in agroforestry. Basul is a legume and so it produces protein-rich beans covered in pods which can be used for human or animal nutrition. The leaves and branches can be used as fodder. Besides the agricultural aspects, Erythrina edulis can also be used as a fence plant.

<i>Crotalaria cunninghamii</i> Species of legume

Crotalaria cunninghamii, also known as green birdflower, birdflower ratulpo, parrot pea or regal birdflower, is a plant of the legume family Fabaceae, named Crotalaria after the Greek word for rattle, because their seeds rattle, and cunninghamii after early 19th century botanist Allan Cunningham. Crotalaria cunninghamii is known as Mangarr to the Nyangumarta Warrarn Indigenous group.

<i>Crotalaria novae-hollandiae</i> Species of plant

Crotalaria novae-hollandiae, known commonly as the New Holland rattlepod, is a species of flowering plant that is native to Australia.

<i>Gynura bicolor</i> Species of flowering plant

Gynura bicolor, hongfeng cai 紅鳳菜, Okinawan spinach or edible gynura, is a member of the chrysanthemum family (Asteraceae). It is native to China, Thailand, and Myanmar but grown in many other places as a vegetable and as a medicinal herb.

<i>Crotalaria retusa</i> Species of plant

Crotalaria retusa is a species of flowering plant in the legume family known by various common names including devil-bean, rattleweed, shack shack, and wedge-leaf rattlepod. It is poisonous to livestock, and contaminates human food. Its original native range is unclear, probably including tropical Asia, Africa and Australia. It has been introduced as a crop plant in many tropical areas and has escaped from cultivation to become a troublesome weed; it is listed as a noxious weed in several US states, Puerto Rico, the Virgin Islands, and is listed as an invasive weed in India, Cuba, and Cocos Island. Unlike some other species of Crotalaria, it is an annual plant.

<i>Crotalaria pallida</i> Species of legume

Crotalaria pallida, commonly known as the smooth crotalaria, is a species of flowering plant within the family Fabaceae.

<span class="mw-page-title-main">Monocrotaline</span> Chemical compound

Monocrotaline (MCT) is a pyrrolizidine alkaloid that is present in plants of the Crotalaria genus. These species can synthesise MCT out of amino acids and can cause liver, lung and kidney damage in various organisms. Initial stress factors are released intracellular upon binding of MCT to BMPR2 receptors and elevated MAPK phosphorylation levels are induced, which can cause cancer in Homo sapiens. MCT can be detoxified in rats via oxidation, followed by glutathione-conjugation and hydrolysis.

References

  1. 1 2 3 Everist, S.L. (1979). Poisonous Plants of Australia (2 ed.). Melbourne, Australia: Angus & Robertson Publishers.
  2. Eisner T. (2003). For the Love of Insects . Belknap Press. ISBN   978-0-674-01827-3.
  3. Bhatt, KC; Pandey, A; Dhariwal, OP; Panwar, NS; Bhandari, DC (2009). ""Tum-thang" (Crotalaria tetragona Roxb. Ex Andr.): a little known wild edible species in the north-eastern hill region of India". Genetic Resources and Crop Evolution. 56 (5): 729–733. doi:10.1007/s10722-009-9428-0. S2CID   36530928.
  4. Johns, T (1996). "Consumption patterns and nutritional contribution of Crotalaria Brevidens (Mitoo) in Tarime District, Tanzania". Ecology of Food and Nutrition. 35 (1): 59–69. doi:10.1080/03670244.1996.9991475.
  5. Morton, JF (1994). "Pito (Erythrina berteroana) and chipilin (Crotalaria longirostrata), (fabaceae) two soporific vegetables of Central America.". Economic Botany. 48 (2): 130–138. doi:10.1007/bf02908199. S2CID   36195369.
  6. Bell, LW; Bennett, RG; Ryan, MH; Clarke, H (2010). "The potential of herbaceous native Australian legumes as grain crops: a review". Renewable Agriculture and Food Systems. 26 (1): 72–91. doi:10.1017/s1742170510000347. S2CID   84659352.
  7. Mannetje, L.'t. "Crotalaria juncea L." FAO (Food and Agriculture Organization of the United Nations). Archived from the original on September 24, 2015. Retrieved October 8, 2015.
  8. Morris, J. Bradley; Antonius, George F. (February 1, 2013). "Glucose, stem dry weight variation, principal components and cluster analysis for some agronomic traits among 16 regenerated Crotalaria juncea accessions for potential cellulosic ethanol". Journal of Environmental Science and Health, Part B. 48 (3): 214–218. doi:10.1080/03601234.2013.730333. PMID   23356343. S2CID   205552940. Archived from the original on July 29, 2020. Retrieved July 14, 2019.
  9. Williams, MC; Molyneux, RJ (1987). "Occurrence, Concentration, and Toxicity of Pyrrolizidine Alkaloids in Crotalaria Seeds". Weed Science. 35 (4): 476–481. doi:10.1017/S0043174500060410. JSTOR   4044515.
  10. Prasad, V.P.; Kothari, M.J.; Barne, K.B.; Rao, P.S.N. (2008). "Congregation of Danaid butteflies on Crotalaria retusa L. (Fabaceae)". Bulletin of the Botanical Survey of India. 50 (104): 193–195. Archived from the original on 2021-09-01. Retrieved 2020-03-13.
  11. "Ração contaminada mata 13 cavalos no DF; outros 17 estão doentes". Archived from the original on 2019-03-22. Retrieved 2019-03-22.
  12. Werchan PM, Summer WR, Gerdes AM, McDonough KH (1989). "Right ventricular performance after monocrotaline-induced pulmonary hypertension". American Journal of Physiology . 256 (5, pt. 2): H1328–H1336. doi:10.1152/ajpheart.1989.256.5.H1328. PMID   2524170.
  13. Kosanovic D, Kojonazarov B, Luitel H, Dahal BK, Sydykov A, Cornitescu T, Janssen W, Brandes RP, Davie N, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT (2011). "Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension". Respiratory Research . 12: 87. doi: 10.1186/1465-9921-12-87 . PMC   3141422 . PMID   21699729.
  14. Arias, L.; Losada, H.; Rendon, A.; Grande, D.; Vieyra, J. (2003). "Evaluation of Chipilin (Crotalaria longirostrata) as a forage resource for ruminant feeding in the tropical areas of Mexico". Livestock Research for Rural Development. 15 (4): 104–115.
  15. Palomino, G.; Vazquez, R. (1991). "Cytogenetic Studies in Mexican Populations of Species of Crotalaria L.". Cytologia. 56 (3): 343–351. doi: 10.1508/cytologia.56.343 .
  16. Abukutsa-Onyango, Mary (28 May 2007). "The Diversity of Cultivated African Leafy Vegetables in Three Communities in Western Kenya". African Journal of Food, Agriculture, Nutrition and Development. 7 (14): 01–15. doi: 10.18697/ajfand.14.IPGRI1-3 . S2CID   56218576.