DPT-Hib vaccine

DPT-Hib vaccine
Combination of
Diphtheria vaccine	Vaccine
Tetanus vaccine	Vaccine
Pertussis vaccine	Vaccine
Hib vaccine	Vaccine
Clinical data
Trade names	Tetramune
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of; administration	Intramuscular injection
ATC code	J07AG52 ( WHO );

Last updated September 21, 2025

DPT-Hib vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and whole-cell pertussis vaccine adsorbed with Hib conjugate vaccine, sometimes abbreviated to DPT-Hib.^[1] It protects against the infectious diseases diphtheria, tetanus, pertussis, and Haemophilus influenzae type B.^[1]

A branded formulation was marketed in the US as Tetramune by Lederle Praxis Biologicals (subsequently acquired by Wyeth).^[2] Tetramune has since been discontinued.^[3]^[4]

References

1 2 "Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed and Haemophilus B Conjugate Vaccine (Systemic)". Drugs.com. Archived from the original on 15 July 2018. Retrieved 15 July 2018.
↑ Centers for Disease Control Prevention (CDC) (April 1993). "FDA approval of use of a new Haemophilus b conjugate vaccine and a combined diphtheria-tetanus-pertussis and Haemophilus b conjugate vaccine for infants and children". MMWR. Morbidity and Mortality Weekly Report. 42 (15). Centers for Disease Control and Prevention: 296–8. PMID 8479415 . Retrieved 15 July 2018.
↑ "Selected Discontinued U.S. Vaccines" (PDF). Centers for Disease Control and Prevention . Retrieved 15 July 2018.
↑ Zarei AE, Almehdar HA, Redwan EM (2016). "Hib Vaccines: Past, Present, and Future Perspectives". Journal of Immunology Research. 2016 7203587. doi: 10.1155/2016/7203587 . PMC 4745871 . PMID 26904695. Table 1

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[Drugs.com-1] 1 2 "Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed and Haemophilus B Conjugate Vaccine (Systemic)". Drugs.com. Archived from the original on 15 July 2018. Retrieved 15 July 2018.

[2] Centers for Disease Control Prevention (CDC) (April 1993). "FDA approval of use of a new Haemophilus b conjugate vaccine and a combined diphtheria-tetanus-pertussis and Haemophilus b conjugate vaccine for infants and children". MMWR. Morbidity and Mortality Weekly Report. 42 (15). Centers for Disease Control and Prevention: 296–8. PMID 8479415 . Retrieved 15 July 2018.

[3] "Selected Discontinued U.S. Vaccines" (PDF). Centers for Disease Control and Prevention . Retrieved 15 July 2018.

[pmid26904695-4] Zarei AE, Almehdar HA, Redwan EM (2016). "Hib Vaccines: Past, Present, and Future Perspectives". Journal of Immunology Research. 2016 7203587. doi: 10.1155/2016/7203587 . PMC 4745871 . PMID 26904695. Table 1

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