| Hypericum glandulosum | |
|---|---|
 | |
Scientific classification  | |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Rosids |
| Order: | Malpighiales |
| Family: | Hypericaceae |
| Genus: | Hypericum |
| Subsection: | H. subsect. Aethiopica |
| Species: | H. glandulosum |
| Binomial name | |
| Hypericum glandulosum | |
Hypericum glandulosum is a perennial herb in the genus Hypericum , in the section Adenosepalum, subsect. Aethiopicum. [1]
According to a study done on the effects of Hypericum glandulosum on mice, the findings have revealed that the aerial component of Hypericum glandulosum in bloom has topical anti-inflammatory, analgesic activities, and anti-depressant properties, suggesting a potential for local medicinal uses in inflammatory illnesses. [2] Because of showing promise as a treatment for cancer, inflammation, bacterial and viral infections, and other conditions, hypericum glandulosum has gained popularity as a mainstream complementary medicine for treating depression.
Hypericum calycinum is a species of prostrate or low-growing shrub in the flowering plant family Hypericaceae. Widely cultivated for its large yellow flowers, its names as a garden plant include Rose-of-Sharon in Britain and Australia, and Aaron's beard, great St-John's wort, creeping St. John's wort and Jerusalem star. Grown in Mediterranean climates, widely spread in the Strandja Mountains along the Bulgarian and Turkish Black Sea coast.
Naproxen, sold under the brand name Aleve among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, gout and fever. It is taken orally. It is available in immediate and delayed release formulations. Onset of effects is within an hour and lasts for up to twelve hours.
Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain.
Thromboxane is a member of the family of lipids known as eicosanoids. The two major thromboxanes are thromboxane A2 and thromboxane B2. The distinguishing feature of thromboxanes is a 6-membered ether-containing ring.
Gingerol, properly as [6]-gingerol, is a phenol phytochemical compound found in fresh ginger that activates spice receptors on the tongue. It is normally found as a pungent yellow oil in the ginger rhizome, but can also form a low-melting crystalline solid. This chemical compound is found in all members of the Zingiberaceae family and is high in concentrations in the grains of paradise as well as an African Ginger species.
Interleukin 19 (IL-19) is an immunosuppressive protein that belongs to the IL-10 cytokine subfamily.
An antileukotriene, also known as leukotriene modifier and leukotriene receptor antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor or leukotriene receptor antagonist and consequently opposes the function of these inflammatory mediators; leukotrienes are produced by the immune system and serve to promote bronchoconstriction, inflammation, microvascular permeability, and mucus secretion in asthma and COPD. Leukotriene receptor antagonists are sometimes colloquially referred to as leukasts.
Chemokine ligand 9 (CCL9) is a small cytokine belonging to the CC chemokine family. It is also called macrophage inflammatory protein-1 gamma (MIP-1γ), macrophage inflammatory protein-related protein-2 (MRP-2) and CCF18, that has been described in rodents. CCL9 has also been previously designated CCL10, although this name is no longer in use. It is secreted by follicle-associated epithelium (FAE) such as that found around Peyer's patches, and attracts dendritic cells that possess the cell surface molecule CD11b and the chemokine receptor CCR1. CCL9 can activate osteoclasts through its receptor CCR1 suggesting an important role for CCL9 in bone resorption. CCL9 is constitutively expressed in macrophages and myeloid cells. The gene for CCL9 is located on chromosome 11 in mice.
Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase enzyme, which is responsible for the production of inflammatory leukotrienes. The overproduction of leukotrienes is a major cause of inflammation in asthma, allergic rhinitis, and osteoarthritis.
Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists (DIGRAs) are a class of experimental drugs designed to share many of the desirable anti-inflammatory, immunosuppressive, or anticancer properties of classical glucocorticoid drugs but with fewer side effects such as skin atrophy. Although preclinical evidence on SEGRAMs’ anti-inflammatory effects are culminating, currently, the efficacy of these SEGRAMs on cancer are largely unknown.
Tetrandrine, a bis-benzylisoquinoline alkaloid, is a calcium channel blocker. It is isolated from the plant Stephania tetrandra, and other Chinese and Japanese herbs.
Gaseous mediators are chemicals that are produced in small amounts by some cells of the mammalian body and have a number of biological signalling functions. There are three so-far-identified gaseous mediator molecules: nitric oxide (NO), hydrogen sulfide (H2S), and carbon monoxide (CO).
Caloptilia aurantiaca is a moth of the family Gracillariidae. It is known from Madeira and the Canary Islands.
Hypericum grandifolium is a species of flowering plant in the St. John's wort family Hypericaceae. It is native to Madeira and the Canary Islands. It is an evergreen shrub up to 1.8 m in height, with dark green, leathery leaves covered with warty glands, and bright yellow flowers up to 4.5 cm broad. It is an important constituent of the shrub layer in the laurisilva of La Gomera.
Lupeol is a pharmacologically active pentacyclic triterpenoid. It has several potential medicinal properties, like anticancer and anti-inflammatory activity.
Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone. It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family.
PF-3845 is a selective inhibitor of fatty acid amide hydrolase. It results in increased levels of anandamide and results in cannabinoid receptor-based effects. It has anti-inflammatory action in mice colitis models. Antidiarrheal and antinociceptive effects were also seen in mouse models of pain.
Hypericum adenotrichum, commonly known as kantaron, is a species of perennial flowering plant in the family Hypericaceae. It is native to Turkey.
Hypericum sect. Adenosepalum is one of 36 sections in the genus Hypericum. Its type species is Hypericum montanum.
Hypericum oblongifolium, known as Pendant St. John's wort, is a species of flowering plant in Hypericumsect. Ascyreia.
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