| 2021 Biella Challenger VI | |
|---|---|
| Date | 17–23 May 2021 |
| Edition | 15th |
| Surface | Clay |
| Location | Biella, Italy |
| Champions | |
| Singles | |
 Thanasi Kokkinakis | |
| Doubles | |
 Evan King /  Julian Lenz | |
The 2021 Biella Challenger VI was a professional tennis tournament played on outdoor red clay courts. It was part of the 2021 ATP Challenger Tour. It took in Biella, Italy between 17 and 23 May 2021.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 ITA | Paolo Lorenzi | 167 | 1 |
 CHN | Zhang Zhizhen | 183 | 2 |
 FRA | Enzo Couacaud | 188 | 3 |
| FRA | Alexandre Müller | 189 | 4 |
 KAZ | Dmitry Popko | 193 | 5 |
| AUS | Alex Bolt | 194 | 6 |
 BRA | João Menezes | 196 | 7 |
| USA | Bjorn Fratangelo | 198 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Riccardo Bonadio 
Tomás Martín Etcheverry Omar Giacalone
Tim van Rijthoven Thanasi Kokkinakis def. Enzo Couacaud 6–3, 6–4. Evan King / Julian Lenz def. 
Karol Drzewiecki / 
Sergio Martos Gornés 3–6, 6–3, [11–9].  | This tennis-related competition article is a stub. You can help Wikipedia by expanding it. |
 | This article related to sports in Italy is a stub. You can help Wikipedia by expanding it. |