| 2021 Challenger Eckental | |
|---|---|
| Date | 1–7 November |
| Edition | 25th |
| Surface | Carpet (Indoor) |
| Location | Eckental, Germany |
| Champions | |
| Singles | |
 Daniel Masur | |
| Doubles | |
 Roman Jebavý /  Jonny O'Mara | |
The 2021 Challenger Eckental was a professional tennis tournament played on carpet courts. It was the 25th edition of the Challenger Eckental, which was part of the 2021 ATP Challenger Tour. It took place in Eckental, Germany, between 1 and 7 November 2021.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 AUS | Jordan Thompson | 71 | 1 |
| CZE | Jiří Veselý | 78 | 2 |
 AUT | Jurij Rodionov | 131 | 3 |
| GER | Oscar Otte | 135 | 4 |
| CZE | Tomáš Macháč | 136 | 5 |
 USA | Maxime Cressy | 141 | 6 |
| GER | |||
 POL | Kacper Żuk | 163 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following players received entry from the qualifying draw:
Johannes Härteis 
Christopher Heyman Tobias Simon Henri Squire The following players received entry as lucky losers:
Daniel Masur def. Maxime Cressy 6–4, 6–4. Roman Jebavý / Jonny O'Mara def. Ruben Bemelmans / Daniel Masur 6–4, 7–5.