| 2021 Zagreb Open | |
|---|---|
| Date | 10–16 May 2021 |
| Edition | 17th |
| Surface | Clay |
| Location | Zagreb, Croatia |
| Champions | |
| Singles | |
| | |
| Doubles | |
| | |
The 2021 Zagreb Open was a professional tennis tournament played on clay courts. It was part of the 2021 ATP Challenger Tour. It took place in Zagreb, Croatia between 10 and 16 May 2021.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| Federico Coria | 92 | 1 | |
| Pedro Martínez | 95 | 2 | |
| Andrej Martin | 109 | 3 | |
| Yasutaka Uchiyama | 110 | 4 | |
| Pedro Sousa | 113 | 5 | |
| Benjamin Bonzi | 115 | 6 | |
| Damir Džumhur | 118 | 7 | |
| Thiago Seyboth Wild | 126 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw: