| 2021 Lima Challenger | |
|---|---|
| Date | 27 September – 3 October |
| Edition | 15th |
| Surface | Clay |
| Location | Lima, Peru |
| Champions | |
| Singles | |
 Hugo Dellien | |
| Doubles | |
 Julian Lenz /  Gerald Melzer | |
The 2021 Lima Challenger was a professional tennis tournament played on clay courts. It was the fifteenth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Lima, Peru between 27 September and 3 October 2021.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 ARG | Francisco Cerúndolo | 103 | 1 |
| ARG | Juan Manuel Cerúndolo | 106 | 2 |
| GER | Daniel Altmaier | 112 | 3 |
 PER | Juan Pablo Varillas | 121 | 4 |
| BOL | Hugo Dellien | 141 | 5 |
| ARG | Renzo Olivo | 202 | 6 |
| ARG | Juan Pablo Ficovich | 236 | 7 |
| ARG | Camilo Ugo Carabelli | 244 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Hugo Dellien def. Camilo Ugo Carabelli 6–3, 7–5. Julian Lenz / Gerald Melzer def. 
Nicolás Barrientos / 
Fernando Romboli 7–6(7–4), 7–6(7–3).The 2016 Claro Open Bucaramanga was a professional tennis tournament played on clay courts. It was the eighth edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Bucaramanga, Colombia between 25 and 31 January 2016.
The 2016 Morelos Open was a professional tennis tournament played on outdoor hard courts. It was the third (ATP) and second (ITF) editions of the tournament, which was part of the 2016 ATP Challenger Tour and the 2016 ITF Women's Circuit, offering prize money of $50,000 (ATP) and $25,000 (ITF) on 15–21 February 2016.
The 2017 Quito Challenger was a professional tennis tournament played on clay courts. It was the 21st edition of the tournament which was part of the 2017 ATP Challenger Tour. It took place in Quito, Ecuador between 28 August and 3 September 2017.
The 2017 Lima Challenger was a professional tennis tournament played on clay courts. It was the eleventh edition of the tournament which was part of the 2017 ATP Challenger Tour. It took place in Lima, Peru between October 23 and October 29, 2017.
The 2018 Monterrey Challenger was a professional tennis tournament played on hard courts. It was the ninth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Monterrey, Mexico from 1 to 7 October 2018.
The 2018 Lima Challenger was a professional tennis tournament played on clay courts. It was the twelfth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Lima, Peru between October 22 and October 27, 2018.
The 2021 Salinas Challenger II was a professional tennis tournament played on green hard courts. It was the 21st edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Salinas, Ecuador between 26 April and 2 May 2021.
The 2021 ATP Salzburg Open was a professional tennis tournament played on outdoor clay courts. It was the first edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Anif (Salzburg), Austria between 5 and 11 July 2021.
The 2021 Ambato La Gran Ciudad was a professional tennis tournament played on clay courts. It was the 1st edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Ambato, Ecuador between 20 and 26 September 2021.
The 2021 Challenger de Santiago II was a professional tennis tournament played on clay courts. It was the 14th edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Santiago, Chile between 4 and 10 October 2021.
The 2021 Challenger de Santiago III was a professional tennis tournament played on clay courts. It was the 15th edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Santiago, Chile between 11 and 17 October 2021.
The 2021 Open Bogotá was a professional tennis tournament played on clay courts. It was the thirteenth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Bogotá, Colombia between 18 and 24 October 2021.
The 2021 Lima Challenger II was a professional tennis tournament played on clay courts. It was the sixteenth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Lima, Peru between 25 and 31 October 2021.
The 2021 São Paulo Challenger de Tênis was a professional tennis tournament played on clay courts. It was the seventh edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in São Paulo, Brazil between 29 November and 5 December 2021.
The 2021 Florianópolis Challenger was a professional tennis tournament played on clay courts. It was the first edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Florianópolis, Brazil from 6 to 12 December 2021.
The 2021 Rio Tennis Classic was a professional tennis tournament played on hard courts. It was the second edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Rio de Janeiro, Brazil from 13 to 19 December 2021.
The 2022 Santa Cruz Challenger II, also known as Dove MEN + CARE Bolivia Open to differentiate it from the previous edition played the same year, was a professional tennis tournament played on clay courts. It was the second edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Santa Cruz de la Sierra, Bolivia between 21 and 27 March 2022.
The 2022 Open Bogotá was a professional tennis tournament played on clay courts. It was the fourteenth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Bogotá, Colombia between 4 and 10 July 2022.
The 2022 República Dominicana Open was a professional tennis tournament played on green clay courts. It was the sixth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Santo Domingo, Dominican Republic between 15 and 21 August 2022.
The 2022 Lima Challenger II was a professional tennis tournament played on clay courts. It was the 18th edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Lima, Peru between 24 and 30 October 2022.
