| 2021 Quito Challenger | |
|---|---|
| Date | 13–19 September |
| Edition | 22nd |
| Surface | Clay |
| Location | Quito, Ecuador |
| Champions | |
| Singles | |
 Facundo Mena | |
| Doubles | |
 Alejandro Gómez / Thiago Agustín Tirante | |
The 2021 Quito Challenger was a professional tennis tournament played on clay courts. It was the 22nd edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Quito, Ecuador between 13 and 19 September 2021.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 SVK | Andrej Martin | 122 | 1 |
 ECU | Emilio Gómez | 161 | 2 |
 ESP | Mario Vilella Martínez | 170 | 3 |
| ARG | Renzo Olivo | 215 | 4 |
| ARG | Juan Pablo Ficovich | 254 | 5 |
| ARG | Facundo Mena | 262 | 6 |
| ARG | Thiago Agustín Tirante | 268 | 7 |
| ECU | Roberto Quiroz | 294 | 8 |
The following players received wildcards into the singles main draw:
Álvaro Guillén Meza Antonio Cayetano March Gian Carlos RodríguezThe following players received entry from the qualifying draw:
Luca Castelnuovo 
Alexis Gautier Alejandro Gómez 
Christian Langmo Facundo Mena def. 
Gonzalo Lama 6–4, 6–4. Alejandro Gómez / Thiago Agustín Tirante def. Adrián Menéndez Maceiras / Mario Vilella Martínez 7–5, 6–7(5–7), [10–8].The 2016 Ecuador Open Quito was an ATP tennis tournament played on outdoor clay courts. It was the 2nd edition of the Ecuador Open Quito as part of the ATP World Tour 250 series of the 2016 ATP World Tour. It took place in Quito, Ecuador from February 1 through February 7, 2016.
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