January 7 – Texas health officials report the state's first case of a new variant of SARS-CoV-2 in a resident of Harris County with no travel history.[1]
January 14 – Texas surpasses two million cases of COVID-19, becoming the second state to do so after California.[2]
March 11 – Texas state Rep. Bryan Slaton introduced a bill that would abolish abortion and make it a criminal act, whereby women and physicians who received and performed abortions, respectively, could receive the death penalty.[5]
Four people are wounded as a gunman opens fire at a high school in Arlington, Texas after a fight. The suspected attacker escaped from the scene, but was arrested several hours later.[7]
December 20 – The United States reports its first confirmed death related to the Omicron variant in an unvaccinated man in his 50s in Harris County, who had underlying health issues.[12]
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