January 3 – Joe Biden drops out of the running for the 2008 U.S. presidential election.
January 5 – A levee bursts in Fernley, Nevada, flooding a large portion of the town and forcing the evacuations of 3,500 residents.
January 7–11 – A tornado outbreak passes through eastern North America, producing at least 75 tornadoes across the mid-eastern United States and record-breaking temperatures in eastern Canada. Four fatalities are reported.
February 1 – The Food and Drug Administration issues a Public Health Advisory on Chantix, an anti-smoking medication, due to a possible "association between Chantix and serious neuropsychiatric symptoms."[6]
The military accidentally kills nine civilians in a raid in Iraq.[7]
An unidentified gunman enters a Tinley Park, IllinoisLane Bryant, taking 6 women hostage and later shooting them all, killing 5 of the 6 women. The shooting currently remains unsolved.[8]
The 2007–2008 Writers Guild of America strike ends effectively at 6:51pm PST (02:51 UTC, February 13) as members vote to stop picket lines in response to a tentative deal reached by the WGA and the AMPTP three days earlier.[18]
February 17 – The USDA recalls 143 million pounds of frozen beef from a California slaughterhouse.[20]
February 20 – The United States Navy destroys an American spy satellite, USA 193, with a missile, prompting international speculation that it is testing its capability to destroy the satellites of other countries.[21]
March 6 – During the early hours of the morning, a small bomb explodes at an unoccupied military recruiting station in Times Square, New York City. No one is injured.
March 13 – The colorized $5 bill is released, with nearly all of the features of the earlier colorized currency (the color-shifting numeral was not added).
March 24 – Relatives of victims of the Virginia Tech massacre report that the government of Virginia will offer victims compensation of $100,000 to forestall lawsuits.
May 7–15 – Several tornadoes cause substantial damage in the Midwestern United States and kill 28 people.
May 12 – A leaked video of Fox News Channel anchor Bill O'Reilly from the early-1990s of him freaking out on camera goes viral on YouTube. In the video, O'Reilly is seen shouting "We'll do it live!"
May 22–31 – A series of tornado outbreaks affecting the central plains of the United States is one of the largest continuous tornado outbreaks on record. A total 239 tornadoes are confirmed. There are 13 fatalities.
Travis Alexander is stabbed multiple times then shot in the forehead by his former girlfriend, Jodi Arias, in Mesa, Arizona. The murder and subsequent trial received widespread media attention.[29][30]
July 18 – The Dark Knight, directed by Christopher Nolan, is released. It was the highest-grossing film of the year, with a worldwide gross of $997,000,000.
August 8 – Former U.S. Senator and vice-presidential and presidential candidate John Edwards admits to an adulterous affair with former campaign worker Rielle Hunter after months of tabloid speculation, but denies being the father of her baby. Edwards would later admit to being the baby's father.
November 21 – Walt Disney Animation Studios' 48th feature film, Bolt, is released. Despite a relatively marginal box-office performance, the film receives the studio's strongest critical reception since 1999's Tarzan and is renowned for playing an important role in instigating what is widely referred to as the Disney Revival, as well as setting the studio in a new creative direction that would lead to other critically acclaimed features such as 2010's Tangled and 2013's Frozen.
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