Ceftiolene

Last updated
Ceftiolene
Ceftiolene.svg
Clinical data
ATC code
  • none
Identifiers
  • (6R,7R)-7-([(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino)-3-[(E)-2-([5,6-dioxo-4-(2-oxoethyl)-1H-1,2,4-triazin-3-yl]sulfanyl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
Chemical and physical data
Formula C20H18N8O8S3
Molar mass 594.59 g·mol−1
3D model (JSmol)
  • CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C=CSC4=NNC(=O)C(=O)N4CC=O)C(=O)O
  • InChI=1S/C20H18N8O8S3/c1-36-26-10(9-7-39-19(21)22-9)13(30)23-11-15(32)28-12(18(34)35)8(6-38-17(11)28)2-5-37-20-25-24-14(31)16(33)27(20)3-4-29/h2,4-5,7,11,17H,3,6H2,1H3,(H2,21,22)(H,23,30)(H,24,31)(H,34,35)/b5-2+,26-10-/t11-,17-/m1/s1
  • Key:WJXAHFZIHLTPFR-JLRJEBFFSA-N
   (verify)

Ceftiolene (INN) is a third-generation cephalosporin antibiotic. [1]

Related Research Articles

<span class="mw-page-title-main">Libra (constellation)</span> Zodiac constellation in the southern celestial hemisphere

Libra is a constellation of the zodiac and is located in the Southern celestial hemisphere. Its name is Latin for weighing scales. Its old astronomical symbol is (♎︎). It is fairly faint, with no first magnitude stars, and lies between Virgo to the west and Scorpius to the east. Beta Librae, also known as Zubeneschamali, is the brightest star in the constellation. Three star systems are known to have planets.

<span class="mw-page-title-main">Coulomb</span> SI derived unit of electric charge

The coulomb (symbol: C) is the unit of electric charge in the International System of Units (SI). In the present version of the SI it is equal to the electric charge delivered by a 1 ampere constant current in 1 second and to 5×1027/801088317 elementary charges, e, (about 6.241509×1018e).

<span class="mw-page-title-main">Messier 103</span> Open cluster in the constellation Cassiopeia

Messier 103 is an open cluster where a few hundred, mainly very faint, stars figure in Cassiopeia. It was discovered in 1781 by Charles Messier's friend and collaborator Pierre Méchain. It is located between 8,000 to 9,500 light-years from the Solar System and ranging over about 15 light years. It holds about 40 certain-member stars, two of which have magnitudes 10.5, and a 10.8 red giant, which is the brightest within the cluster. A bright known foreground object is the star Struve 131, not a member of the cluster. The cluster may have 172 stars if including those down to 50% probability of a gravitational tie. M103 is about 22 million years old.

<i>The F.B.I.</i> (TV series) American television series

The F.B.I. is an American police television series created by Quinn Martin and Philip Saltzman for ABC and co-produced with Warner Bros. Television, with sponsorship from the Ford Motor Company, Alcoa and American Tobacco Company in the first season. Ford sponsored the show alone for subsequent seasons. The series was broadcast on ABC from 1965 until its end in 1974. Starring Efrem Zimbalist, Jr., Philip Abbott and William Reynolds, the series, consisting of nine seasons and 241 episodes, chronicles a group of FBI agents trying to defend the US Government from unidentified threats. For the entirety of its run, it was broadcast on Sunday nights.

<span class="mw-page-title-main">Cadalso</span> Place in Extremadura, Spain

Cadalso is a small village in the west of Spain, near Portugal. It is situated on the Sierra de Gata in Northwest of province of Cáceres, autonomous community of Extremadura. Its population in 2003 was 581. The major livelihoods of the area consist of agriculture, olive oil, goats and pines.

<span class="mw-page-title-main">Far North District</span> Territorial authority district in Northland Region, New Zealand

The Far North District is the northernmost territorial authority district of New Zealand, consisting of the northern part of the Northland Peninsula in the North Island. It stretches from North Cape and Cape Reinga / Te Rerenga Wairua in the north, down to the Bay of Islands, the Hokianga and the town of Kaikohe.

Gliese 581 is a red dwarf star of spectral type M3V at the center of the Gliese 581 planetary system, about 20.5 light years away from Earth in the Libra constellation. Its estimated mass is about a third of that of the Sun, and it is the 101st closest known star system to the Sun. Gliese 581 is one of the oldest, least active M dwarfs known. Its low stellar activity improves the likelihood of its planets retaining significant atmospheres, and lessens the sterilizing impact of stellar flares.

<span class="mw-page-title-main">1997 Salvadoran legislative election</span> 1997 elections in El Salvador

Legislative elections were held in El Salvador on 16 March 1997. The result was a narrow victory for the Nationalist Republican Alliance, which won 28 of the 84 seats. Voter turnout was 39.2%.

<span class="mw-page-title-main">Gliese 581b</span> Gas giant orbiting Gliese 581

Gliese 581b or Gl 581b is an extrasolar planet orbiting within the Gliese 581 system. It is the first planet discovered of three confirmed in the system so far, and the second in order from the star.

<span class="mw-page-title-main">European route E58</span> Road in trans-European E-road network

European route E 58 is a road part of the International E-road network. It begins in Vienna, Austria and ends in Rostov-na-Donu, Russia. It is approximately 2,200 km (1,400 mi) long.

<span class="mw-page-title-main">Gliese 581c</span> Super-Earth exoplanet orbiting Gliese 581

Gliese 581c is a planet orbiting within the Gliese 581 system. It is the second planet discovered in the system and the third in order from the star. With a mass at least 5.5 times that of the Earth, it is classified as a super-Earth.

<span class="mw-page-title-main">Gliese 581d</span> Contested super-Earth orbiting Gliese 581

Gliese 581d is a proposed extrasolar planet orbiting within the Gliese 581 system, approximately 20.4 light-years away in the Libra constellation. It is the third planet claimed in the system and the fifth in order from the star.

<span class="mw-page-title-main">Area codes 418, 581, and 367</span> Area codes covering eastern Quebec, Canada

Area codes 418, 581, and 367 are telephone area codes in the North American Numbering Plan (NANP) for the eastern portion of the Canadian province of Quebec. Area code 418 was originally assigned to the numbering plan area, but all three area codes now form an overlay plan for this territory. Cities in the numbering plan area include Quebec City, Saguenay, Lévis, Rimouski, Saint-Georges, Alma, Thetford Mines, Sept-Îles, Baie-Comeau and Rivière-du-Loup. Also served are the Gaspé Peninsula, Côte-Nord, southeastern Mauricie, and the tiny hamlet of Estcourt Station, in the U.S. state of Maine.

<span class="mw-page-title-main">581st Air Resupply and Communications Wing</span> Military unit

The 581st Air Resupply and Communications Wing was a United States Air Force special operations wing, last assigned to Thirteenth Air Force at Clark Air Base, Philippines, from 1951-53.

<span class="mw-page-title-main">583 series</span> Japanese train type

The 581/583 series (581/583系) were limited express electric multiple unit (EMU) train types introduced in 1967 by Japanese National Railways and later operated by East Japan Railway Company and West Japan Railway Company on the through services express Kitaguni and other special trains until 2017.

<span class="mw-page-title-main">North Carolina Highway 581</span> State highway in North Carolina, US

North Carolina Highway 581 (NC 581) is a primary state highway in the U.S. state of North Carolina. The highway travels from Goldsboro to Louisburg, connecting various rural communities in between.

<span class="mw-page-title-main">Gliese 581g</span> Former candidate super-Earth orbiting Gliese 581

Gliese 581g, unofficially known as Zarmina, was a candidate exoplanet postulated to orbit within the Gliese 581 system, twenty light-years from Earth. It was discovered by the Lick–Carnegie Exoplanet Survey, and was the sixth planet claimed to orbit the star; however, its existence could not be confirmed by the European Southern Observatory (ESO) / High Accuracy Radial Velocity Planet Searcher (HARPS) survey team, and was ultimately refuted. It was thought to be near the middle of the habitable zone of its star, meaning it could sustain liquid water—a necessity for all known life—on its surface, if there are favorable atmospheric conditions on the planet.

German submarine U-581 was a Type VIIC U-boat of Nazi Germany's Kriegsmarine during World War II.

Papyrus Oxyrhynchus 581 is a papyrus fragment written in Ancient Greek, apparently recording the sale of a slave girl. Dating from 29 August 99 AD, P. Oxy. 581 was discovered, alongside hundreds of other papyri, by Bernard Pyne Grenfell and Arthur Surridge Hunt while excavating an ancient landfill at Oxyrhynchus in modern Egypt. The document's contents were published by the Egypt Exploration Fund in 1898, which also secured its donation to University College, Dundee, later the University of Dundee, in 1903 – where it still resides. Measuring 6.3 x 14.7 cm and consisting of 17 lines of text, the artifact represents the conclusion of a longer record, although the beginning of the papyrus was lost before it was found. P. Oxy. 581 has received a modest amount of scholarly attention, most recently and completely in a 2009 translation by classicist Amin Benaissa of Lady Margaret Hall, Oxford.

References

  1. Williamson R, Gutmann L, Kitzis MD, Acar JF (December 1984). "An evaluation of the bacteriolytic and biochemical properties of ceftiolene (42980RP)". The Journal of Antimicrobial Chemotherapy. 14 (6): 581–93. doi:10.1093/jac/14.6.581. PMID   6394571.