|
| By-election | Date | Former incumbent | Party | Winner | Party | Cause |
|---|
| Tipperary | 16 March 1857 | James Sadleir | | Independent Irish | Daniel O'Donoghue | | Independent Irish | Expulsion (Absconded to avoid charges for fraud) |
| County Londonderry | 9 March 1857 | Thomas Bateson | | Conservative | James Johnston Clark | | Conservative | Resignation |
| East Sussex | 7 March 1857 | Charles Frewen | | Conservative | Viscount Pevensey | | Conservative | Resignation (intended to contest North Leicestershire) |
| Glasgow | 6 March 1857 | John MacGregor | | Whig | Walter Buchanan | | Whig | Resignation |
| North Leicestershire | 2 March 1857 [16 1] | Marquess of Granby | | Conservative | Lord John Manners | | Conservative | Succession to a peerage |
| Colchester | 24 February 1857 [16 1] | Lord John Manners | | Conservative | John Gurdon Rebow | | Whig | Resignation in order to contest North Leicestershire |
| County Limerick | 17 February 1857 [16 1] | William Monsell | | Whig | William Monsell | | Whig | President of the Board of Health [16 2] |
| Clonmel | 17 February 1857 | John O'Connell | | Whig | John Bagwell | | Whig | Resignation (Clerk of the Crown and Hanaper in Ireland) |
| West Kent | 16 February 1857 [16 1] | Sir Edmund Filmer | | Conservative | Charles Wykeham Martin | | Whig | Death |
| Hereford | 14 February 1857 | Sir Robert Price | | Whig | George Clive | | Whig | Resignation |
| Bandon | 14 February 1857 | Viscount Bernard | | Conservative | William Smyth Bernard | | Conservative | Succession to an Irish peerage |
| Dumfriesshire | 12 February 1857 [16 1] | Viscount Drumlanrig | | Conservative | John Hope-Johnstone | | Conservative | Succession to a Scottish peerage |
| Downpatrick | 12 February 1857 | Charles Hardinge | | Conservative | Richard Ker | | Conservative | Succession to a peerage |
| Buteshire | 12 February 1857 [16 1] | James Stuart-Wortley | | Peelite | James Stuart-Wortley | | Peelite | Solicitor General for England and Wales [16 2] |
| Southampton | 11 February 1857 | Alexander Cockburn | | Whig | Thomas Matthias Weguelin | | Whig | Resignation (Chief Justice of the Common Pleas) |
| Newport (I.O.W.) | 11 February 1857 | William Biggs | | Whig | Robert Kennard | | Conservative | Resignation |
| Kingston upon Hull | 11 February 1857 [16 1] | William Henry Watson | | Whig | James Clay | | Whig | Resignation (Baron of the Court of Exchequer) |
| Hertford | 9 February 1857 [16 1] | William Cowper | | Whig | William Cowper | | Whig | Vice-President of the Committee of the Council on Education [16 2] |
| Greenwich | 9 February 1857 | Peter Rolt | | Conservative | William Codrington | | Whig | Resignation |
| Aylesbury | 9 February 1857 [16 1] | Richard Bethell | | Whig | Richard Bethell | | Whig | Attorney General for England and Wales [16 2] |
| Salford | 2 February 1857 [16 1] | Joseph Brotherton | | Whig | Edward Ryley Langworthy | | Ind. Whig [1] | Death |
| Lanarkshire | 9 January 1857 [16 1] | William Lockhart | | Conservative | Alexander Baillie-Cochrane | | Conservative | Death |
| East Suffolk | 26 December 1856 [16 1] | Sir Edward Gooch | | Conservative | The Lord Henniker | | Conservative | Death |
| Kerry | 9 August 1856 [16 1] | Viscount Castlerosse | | Whig | Viscount Castlerosse | | Whig | Comptroller of the Household [16 2] |
| Nottingham | 30 July 1856 [16 1] | Edward Strutt | | Whig | Charles Paget | | Whig | Resignation and elevation to the peerage |
| Dorset | 26 July 1856 [16 1] | George Bankes | | Conservative | Henry Sturt | | Conservative | Death |
| Frome | 23 July 1856 | Viscount Dungarvan | | Whig | William George Boyle | | Whig | Succession to a peerage |
| Dorchester | 22 July 1856 [16 1] | Henry Sturt | | Conservative | Charles Napier Sturt | | Conservative | Resignation in order to contest Dorset |
| Calne | 9 July 1856 [16 1] | Earl of Shelburne | | Whig | Sir William Fenwick Williams | | Whig | Resignation and elevation to the House of Lords through a Writ of acceleration |
| Leicester | 18 June 1856 [16 1] | Richard Gardner | | Whig | John Biggs | | Whig | Death |
| Lichfield | 30 May 1856 [16 1] | The Lord Waterpark | | Whig | Viscount Sandon | | Ind. Whig [2] [3] | Resignation |
| Longford | 13 May 1856 [16 1] | Richard Maxwell Fox | | Whig | Henry George Hughes | | Whig | Death |
| Cheltenham | 8 May 1856 | Grenville Berkeley | | Whig | Francis Berkeley | | Whig | Resignation |
| Athlone | 14 April 1856 | William Keogh | | Whig | Henry Handcock | | Conservative | Resignation (Judge of the Court of Common Pleas) |
| Chippenham | 9 April 1856 [16 1] | Joseph Neeld | | Conservative | Robert Parry Nisbet | | Conservative | Death |
| Ennis | 8 April 1856 [16 1] | John David FitzGerald | | Whig | John David FitzGerald | | Whig | Attorney-General for Ireland [16 2] |
| Boston | 7 March 1856 | Gilbert Heathcote | | Whig | Herbert Ingram | | Whig | Resignation in order to contest Rutlandshire |
| Rutlandshire | 4 March 1856 [16 1] | Sir Gilbert Heathcote | | Whig | Gilbert Heathcote | | Whig | Resignation and elevation to the peerage |
| Leominster | 19 February 1856 | George Arkwright | | Conservative | Gathorne Hardy | | Conservative | Death |
| New Ross | 18 February 1856 | Charles Gavan Duffy | | Independent Irish | Charles Tottenham | | Conservative | Resignation |
| Cambridge University | 11 February 1856 | Henry Goulburn | | Conservative | Spencer Horatio Walpole | | Conservative | Death |
| Wigtownshire | 9 February 1856 [16 1] | Viscount Dalrymple | | Whig | Sir Andrew Agnew | | Whig | Resignation |
| Edinburgh | 9 February 1856 | Thomas Babington Macaulay | | Whig | Adam Black | | Whig | Resignation |
| Sligo Borough | 8 February 1856 | John Sadleir | | Whig | John Arthur Wynne | | Conservative | Death |
| Rochester | 8 February 1856 | Francis Child Villiers | | Conservative | Philip Wykeham Martin | | Whig | Resignation |
| Tamworth | 7 February 1856 [16 1] | John Townshend | | Whig | Viscount Raynham | | Whig | Succession to a peerage |
| Midhurst | 7 February 1856 [16 1] | Spencer Horatio Walpole | | Conservative | Samuel Warren | | Conservative | Resignation in order to contest Cambridge University |
| Leeds | 6 February 1856 [16 1] | Matthew Talbot Baines | | Whig | Matthew Talbot Baines | | Whig | Chancellor of the Duchy of Lancaster [16 2] |
| Taunton | 5 February 1856 [16 1] | Henry Labouchere | | Whig | Henry Labouchere | | Whig | Secretary of State for the Colonies [16 2] |
| Newcastle upon Tyne | 5 February 1856 [16 1] | John Fenwick Burgoyne Blackett | | Whig | George Ridley | | Whig | Resignation |
| Lincoln | 16 January 1856 [16 1] | Charles Delaet Waldo Sibthorp | | Conservative | Gervaise Tottenham Waldo Sibthorp | | Conservative | Death |
| Meath | 17 December 1855 | Frederick Lucas | | Independent Irish | Edward McEvoy | | Independent Irish | Death |
| Armagh City | 6 December 1855 | Ross Stephenson Moore | | Conservative | Joshua Bond | | Conservative | Death |
| Wells | 21 November 1855 | Robert Charles Tudway | | Conservative | Hedworth Hylton Jolliffe | | Conservative | Death |
| Southwark | 20 November 1855 [16 1] | Sir William Molesworth | | Radical | Charles Napier | | Whig | Death |
| Totnes | 5 November 1855 [16 1] | Lord Seymour | | Whig | Earl of Gifford | | Whig | Succession to a peerage |
| Huntingdonshire | 23 October 1855 [16 1] | Viscount Mandeville | | Conservative | James Rust | | Conservative | Succession to a peerage |
| Kilmarnock Burghs | 16 August 1855 [16 1] | Edward Pleydell-Bouverie | | Whig | Edward Pleydell-Bouverie | | Whig | President of the Poor Law Board [16 2] |
| Kidderminster | 14 August 1855 [16 1] | Robert Lowe | | Whig | Robert Lowe | | Whig | Vice-President of the Board of Trade and Paymaster General [16 2] |
| Hertford | 14 August 1855 [16 1] | William Cowper | | Whig | William Cowper | | Whig | President of the Board of Health [16 2] |
| Marylebone | 28 July 1855 [16 1] | Sir Benjamin Hall | | Peelite | Sir Benjamin Hall | | Peelite | First Commissioner of Works [16 2] |
| Southwark | 27 July 1855 [16 1] | Sir William Molesworth | | Radical | Sir William Molesworth | | Radical | Secretary of State for the Colonies [16 2] |
| East Norfolk | 17 July 1855 [16 1] | Edmond Wodehouse | | Conservative | Sir Henry Stracey | | Conservative | Resignation |
| Cheltenham | 14 July 1855 | Craven Berkeley | | Whig | Grenville Berkeley | | Whig | Death |
| Evesham | 11 July 1855 [16 1] | Grenville Berkeley | | Whig | Edward Holland | | Whig | Resignation in order to contest Cheltenham |
| Bath | 5 June 1855 | Thomas Phinn | | Whig | William Tite | | Whig | Resignation |
| Renfrewshire | 14 May 1855 [16 1] | William Mure | | Conservative | Sir Michael Shaw-Stewart | | Conservative | Resignation |
| County Cork | 23 April 1855 | Edmond Roach | | Whig | Rickard Deasy | | Whig | Resignation and elevation to the Irish peerage |
| Cavan | 13 April 1855 | Sir John Young | | Peelite | Robert Burrowes | | Conservative | Resignation (Lord High Commissioner of the Ionian Islands) |
| Kilmarnock Burghs | 7 April 1855 [16 1] | Edward Pleydell-Bouverie | | Whig | Edward Pleydell-Bouverie | | Whig | Vice-President of the Board of Trade and Paymaster General [16 2] |
| Lewes | 5 April 1855 [16 1] | Henry Brand | | Whig | Henry Brand | | Whig | Junior Lord of the Treasury [16 2] |
| Gloucester | 31 March 1855 [16 1] | William Philip Price | | Whig | William Philip Price | | Whig | Seeks re-election after his firm was granted a contract to supply huts to the army in the Crimea |
| Liverpool | 29 March 1855 | Henry Thomas Liddell | | Conservative | Joseph Christopher Ewart | | Whig | Succession to a peerage |
| Wilton | 28 March 1855 [16 1] | Charles A'Court | | Whig | Edmund Antrobus | | Whig | Resignation (Special Commissioner of Property and Income Tax) |
| Tamworth | 14 March 1855 [16 1] | Sir Robert Peel | | Peelite | Sir Robert Peel | | Peelite | Civil Lord of the Admiralty [16 2] |
| Portsmouth | 14 March 1855 | The Viscount Monck | | Whig | The Viscount Monck | | Whig | Junior Lord of the Treasury [16 2] |
| Forfarshire | 10 March 1855 [16 1] | Viscount Duncan | | Whig | Viscount Duncan | | Whig | Junior Lord of the Treasury [16 2] |
| Barnstaple | 10 March 1855 [16 1] | John Laurie | | Conservative | George Buck | | Conservative | Void By-Election |
| Montrose Burghs | 9 March 1855 | Joseph Hume | | Whig | William Edward Baxter | | Whig | Death |
| Ennis | 8 March 1855 [16 1] | John David FitzGerald | | Independent Irish | John David FitzGerald | | Whig | Solicitor-General for Ireland [16 2] |
| Dudley | 8 March 1855 | John Benbow | | Conservative | Sir Stafford Northcote | | Conservative | Death |
| Athlone | 7 March 1855 [16 1] | William Keogh | | Whig | William Keogh | | Whig | Attorney-General for Ireland [16 2] |
| Stroud | 6 March 1855 [16 1] | Edward Horsman | | Whig | Edward Horsman | | Whig | Chief Secretary for Ireland [16 2] |
| Stirlingshire | 5 March 1855 [16 1] | William Forbes | | Conservative | Peter Blackburn | | Conservative | Death |
| Radnor Boroughs | 5 March 1855 [16 1] | George Cornewall Lewis | | Whig | George Cornewall Lewis | | Whig | Chancellor of the Exchequer [16 2] |
| Northampton | 5 March 1855 [16 1] | Robert Vernon Smith | | Whig | Robert Vernon Smith | | Whig | President of the Board of Control [16 2] |
| Halifax | 3 March 1855 [16 1] | Sir Charles Wood | | Whig | Sir Charles Wood | | Whig | First Lord of the Admiralty [16 2] |
| City of London | 3 March 1855 [16 1] | Lord John Russell | | Whig | Lord John Russell | | Whig | Secretary of State for the Colonies [16 2] |
| Swansea District | 27 February 1855 [16 1] | John Henry Vivian | | Whig | Lewis Llewelyn Dillwyn | | Whig | Death |
| Cardigan Boroughs | 24 February 1855 | Pryse Loveden | | Whig | John Lloyd Davies | | Conservative | Death |
| South Wiltshire | 15 February 1855 [16 1] | Sidney Herbert | | Peelite | Sidney Herbert | | Peelite | Secretary of State for the Colonies [16 2] |
| Windsor | 14 February 1855 [16 1] | Lord Charles Wellesley | | Conservative | Samson Ricardo | | Whig | Resignation |
| Tiverton | 12 February 1855 [16 1] | The Viscount Palmerston | | Whig | The Viscount Palmerston | | Whig | Prime Minister and First Lord of the Treasury [16 2] |
| Radnor Boroughs | 8 February 1855 [16 1] | Sir Thomas Frankland Lewis | | Whig | George Cornewall Lewis | | Whig | Death |
| Sunderland | 2 January 1855 | William Digby Seymour | | Whig | Henry Fenwick | | Whig | Recorder of Newcastle [16 2] |
| Ayrshire | 30 December 1854 | James Hunter Blair | | Conservative | Sir James Fergusson | | Conservative | Death |
| Norwich | 29 December 1854 | Samuel Morton Peto | | Whig | Samuel Bignold | | Conservative | Resignation |
| Fermanagh | 29 December 1854 [16 1] | Sir Arthur Brooke | | Conservative | Henry Cole | | Conservative | Death |
| Antrim | 27 December 1854 [16 1] | Edward William Pakenham | | Conservative | Thomas Henry Pakenham | | Conservative | Death |
| County Limerick | 26 December 1854 [16 1] | Wyndham Goold | | Whig | Stephen de Vere | | Whig | Death |
| Marylebone | 20 December 1854 | Lord Dudley Stuart | | Whig | Viscount Ebrington | | Whig | Death |
| East Gloucestershire | 19 December 1854 | Sir Michael Hicks Beach | | Conservative | Robert Stayner Holford | | Conservative | Death |
| Abingdon | 13 December 1854 | Lord Norreys | | Whig | Joseph Haythorne Reed | | Whig | Succession to a peerage |
| Bedford | 6 December 1854 | Henry Stuart | | Conservative | William Stuart | | Conservative | Death |
| Coventry | 2 December 1854 [16 1] | Charles Geach | | Whig | Joseph Paxton | | Whig | Death |
| Limerick City | 28 October 1854 [16 1] | Robert Potter | | Independent Irish | James O'Brien | | Whig | Death |
| Frome | 24 October 1854 | Robert Edward Boyle | | Whig | Viscount Dungarvan | | Whig | Death |
| Forfarshire | 11 October 1854 [16 1] | Lauderdale Maule | | Whig | Viscount Duncan | | Whig | Death |
| Wigan | 3 October 1854 | Ralph Anthony Thicknesse | | Whig | Joseph Acton | | Whig | Death |
| King's Lynn | 16 September 1854 [16 1] | Viscount Jocelyn | | Conservative | John Henry Gurney | | Whig | Death |
| Barnstaple | 25 August 1854 | Richard Bremridge | | Conservative | John Laurie | | Conservative | Void election |
| Sir William Fraser | | Conservative | Richard Samuel Guinness | | Conservative | Void election |
| Aberdeenshire | 22 August 1854 [16 1] | William Gordon | | Conservative | Lord Haddo | | Whig | Resignation |
| Kingston upon Hull | 18 August 1854 | Viscount Goderich | | Whig | William Henry Watson | | Whig | Void election |
| James Clay | | Whig | William Digby Seymour | | Whig | Void election |
| Canterbury | 18 August 1854 | Henry Plumptre Gipps | | Conservative | Charles Manners Lushington | | Conservative | Void election |
| Henry Butler-Johnstone | | Conservative | Sir William Somerville | | Whig | Void election |
| Cambridge | 18 August 1854 | Kenneth Macaulay | | Conservative | Robert Adair | | Whig | Void election |
| John Harvey Astell | | Conservative | Francis Mowatt | | Whig | Void election |
| Maldon | 17 August 1854 | Charles Du Cane | | Conservative | George Sandford | | Conservative | Void election |
| Taverner John Miller | | Conservative | John Bramley-Moore | | Conservative | Void election |
| Marylebone | 16 August 1854 [16 1] | Sir Benjamin Hall | | Whig | Sir Benjamin Hall | | Whig | President of the Board of Health [16 2] |
| Cockermouth | 9 August 1854 [16 1] | Henry Aglionby Aglionby | | Whig | John Steel | | Whig | Death |
| Beverley | 31 July 1854 | Francis Charles Lawley | | Whig | Arthur Hamilton-Gordon | | Whig | Resignation |
| Morpeth | 17 June 1854 [16 1] | Sir George Grey | | Whig | Sir George Grey | | Whig | Secretary of State for the Colonies [16 2] |
| City of London | 14 June 1854 [16 1] | Lord John Russell | | Whig | Lord John Russell | | Whig | Lord President of the Council [16 2] |
| Hertfordshire | 24 May 1854 | Thomas Plumer Halsey | | Conservative | Abel Smith, Jnr | | Conservative | Death |
| Devonport | 11 May 1854 | Henry Tufnell | | Whig | Thomas Erskine Perry | | Whig | Resignation |
| Hastings | 10 May 1854 [16 1] | Musgrave Brisco | | Conservative | Frederick North | | Whig | Resignation |
| Lichfield | 9 May 1854 [16 1] | Viscount Anson | | Whig | The Lord Waterpark | | Whig | Succession to a peerage |
| Flintshire | 8 May 1854 [16 1] | Edward Lloyd-Mostyn | | Whig | Thomas Lloyd-Mostyn | | Whig | Succession to a peerage |
| Southampton | 12 April 1854 [16 1] | Alexander Cockburn | | Whig | Alexander Cockburn | | Whig | Recorder of Bristol [16 2] |
| North Durham | 1 April 1854 [16 1] | Viscount Seaham | | Conservative | Lord Adolphus Vane-Tempest | | Conservative | Succession to a peerage |
| Westmorland | 31 March 1854 [16 1] | William Thompson | | Conservative | Earl of Bective | | Conservative | Death |
| Tynemouth and North Shields | 30 March 1854 | Hugh Taylor | | Conservative | William Schaw Lindsay | | Whig | Void election |
| Liskeard | 29 March 1854 | Richard Budden Crowder | | Whig | Ralph William Grey | | Whig | Resignation (Judge of the Court of Common Pleas) |
| Louth | 27 February 1854 | Chichester Fortescue | | Whig | Chichester Fortescue | | Whig | Junior Lord of the Treasury [16 2] |
| Cardiganshire | 22 February 1854 [16 1] | William Edward Powell | | Conservative | The Earl of Lisburne | | Conservative | Resignation |
| South Devon | 14 February 1854 [16 1] | Sir Ralph Lopes | | Conservative | Lawrence Palk | | Conservative | Death |
| West Sussex | 13 February 1854 [16 1] | Richard Prime | | Conservative | Henry Wyndham | | Conservative | Resignation |
| South Staffordshire | 8 February 1854 | Viscount Lewisham | | Conservative | Lord Paget | | Whig | Succession to a peerage |
| South Shropshire | 8 February 1854 [16 1] | Robert Clive | | Conservative | Robert Windsor-Clive | | Conservative | Death |
| Oxford University | 7 February 1854 [16 1] | Robert Inglis | | Conservative | Sir William Heathcote, | | Conservative | Resignation |
| Ludlow | 7 February 1854 [16 1] | Robert Windsor-Clive | | Conservative | Percy Egerton Herbert | | Conservative | Resignation in order to contest South Shropshire |
| Brecon | 6 February 1854 [16 1] | Charles Rodney Morgan | | Conservative | John Lloyd Vaughan Watkins | | Whig | Death |
| East Gloucestershire | 9 January 1854 [16 1] | Marquess of Worcester | | Conservative | Sir Michael Hicks Beach | | Conservative | Succession to a peerage |
| Clonmel | 21 December 1853 [16 1] | Cecil Lawless | | Independent Irish | John O'Connell | | Whig | Death |
| South Warwickshire | 3 December 1853 [16 1] | Lord Brooke | | Whig | Evelyn Shirley | | Whig | Succession to a peerage |
| Salisbury | 15 November 1853 | Charles Baring Wall | | Whig | Edward Pery Buckley | | Whig | Death |
| Lisburn | 14 October 1853 [16 1] | Roger Johnson Smyth | | Peelite | Jonathan Joseph Richardson | | Whig | Death |
| Dungarvan | 26 August 1853 | John Francis Maguire | | Independent Irish | John Francis Maguire | | Independent Irish | Seeks re-election upon becoming Mayor of Cork |
| Clitheroe | 23 August 1853 | John Thomas Walshman Aspinall | | Conservative | Le Gendre Starkie | | Whig | Void By-Election |
| Stamford | 22 August 1853 [16 1] | John Charles Herries | | Conservative | Lord Robert Cecil | | Conservative | Resignation |
| Cork City | 20 August 1853 | Francis Murphy | | Whig | Francis Beamish | | Whig | Resignation (Commissioner for the Relief of Insolvent Debtors in England) |
| South Staffordshire | 15 August 1853 [16 1] | George Anson | | Whig | Edward Littleton | | Whig | Resignation |
| North Derbyshire | 22 July 1853 | William Evans | | Whig | William Pole Thornhill | | Ind. Whig [4] [5] | Resignation |
| West Cornwall | 18 July 1853 [16 1] | Edward Wynne-Pendarves | | Whig | Michael Williams | | Whig | Death |
| Liverpool | 9 July 1853 | Charles Turner | | Conservative | Thomas Horsfall | | Conservative | Void election |
| William Forbes Mackenzie | | Conservative | Henry Liddell | | Conservative | Void election |
| Sligo Borough | 8 July 1853 | Charles Towneley | | Independent Irish | John Sadleir | | Whig | Void election |
| Tralee | 4 July 1853 | Maurice O'Connell | | Whig | Daniel O'Connell Jnr | | Whig | Death |
| Clare | 4 July 1853 | John Forster FitzGerald | | Whig | John Forster FitzGerald | | Whig | Void election |
| Cornelius O'Brien | | Independent Irish | Cornelius O'Brien | | Independent Irish | Void election |
| Stroud | 28 June 1853 [16 1] | Lord Moreton | | Whig | Edward Horsman | | Whig | Succession to a peerage |
| Peterborough | 25 June 1853 | George Hammond Whalley | | Whig | George Hammond Whalley | | Whig | Void By-Election |
| George Hammond Whalley | | Whig | Thomson Hankey | | Whig | By-election result reversed on petition |
| Edinburghshire | 25 June 1853 [16 1] | John Hope | | Conservative | Earl of Dalkeith | | Conservative | Void election |
| City Durham | 25 June 1853 | Lord Adolphus Vane | | Conservative | John Mowbray | | Conservative | Void By-Election |
| Chatham | 23 June 1853 | John Mark Frederick Smith | | Conservative | Leicester Viney Vernon | | Conservative | Void election |
| Harwich | 21 June 1853 | George Sandford | | Conservative | John Bagshaw | | Whig | Void election |
| Plymouth | 2 June 1853 | Charles John Mare | | Conservative | Roundell Palmer | | Conservative | Void election |
| Clitheroe | 28 May 1853 | Mathew Wilson | | Whig | John Thomas Walshman Aspinall | | Conservative | Void election |
| Rye | 23 May 1853 | William Alexander Mackinnon (younger) | | Whig | William Alexander Mackinnon (elder) | | Whig | Void election |
| Maidstone | 16 May 1853 | George Dodd | | Conservative | William Lee | | Whig | Void election |
| Berwick-upon-Tweed | 14 May 1853 | John Stapleton | | Whig | Dudley Marjoribanks | | Whig | Void election |
| Matthew Forster | | Whig | John Forster | | Whig | Void election |
| Taunton | 4 May 1853 | Arthur Mills | | Conservative | Sir John Ramsden | | Whig | Void election |
| County Carlow | 25 April 1853 [16 1] | Henry Bruen | | Conservative | William McClintock-Bunbury | | Conservative | Death |
| Athlone | 23 April 1853 | William Keogh | | Independent Irish | William Keogh | | Whig | Solicitor-General for Ireland [16 2] |
| Huddersfield | 22 April 1853 | William Rookes Crompton Stansfield | | Whig | Viscount Goderich | | Whig | Void election |
| Lancaster | 12 April 1853 | Robert Baynes Armstrong | | Whig | Thomas Greene | | Conservative | Void election |
| Blackburn | 24 March 1853 | William Eccles | | Whig | Montague Joseph Feilden | | Whig | Void election |
| Bridgnorth | 22 March 1853 [16 1] | Sir Robert Pigot | | Conservative | John Pritchard | | Conservative | Void election |
| Frome | 7 March 1853 [16 1] | Robert Edward Boyle | | Whig | Robert Edward Boyle | | Whig | Void election |
| West Worcestershire | 28 February 1853 [16 1] | Henry Lygon | | Conservative | Viscount Elmley | | Conservative | Succession to a peerage |
| Forfarshire | 25 February 1853 [16 1] | Lauderdale Maule | | Whig | Lauderdale Maule | | Whig | Surveyor-General of the Ordnance [16 2] |
| Oxford University | 20 January 1853 | William Ewart Gladstone | | Peelite | William Ewart Gladstone | | Peelite | Chancellor of the Exchequer [16 2] |
| Carlow Borough | 20 January 1853 | John Sadleir | | Independent Irish | John Alexander | | Conservative | Junior Lord of the Treasury [16 2] |
| County Limerick | 12 January 1853 [16 1] | William Monsell | | Whig | William Monsell | | Whig | Clerk of the Ordnance [16 2] |
| Dumfriesshire | 12 January 1853 [16 1] | Viscount Drumlanrig | | Peelite | Viscount Drumlanrig | | Peelite | Comptroller of the Household [16 2] |
| South Wiltshire | 11 January 1853 [16 1] | Sidney Herbert | | Peelite | Sidney Herbert | | Peelite | Secretary at War [16 2] |
| Haddingtonshire | 11 January 1853 [16 1] | Lord Elcho | | Peelite | Lord Elcho | | Peelite | Junior Lord of the Treasury [16 2] |
| Cavan | 10 January 1853 [16 1] | Sir John Young | | Peelite | Sir John Young | | Peelite | Chief Secretary for Ireland [16 2] |
| Southampton | 7 January 1853 | Sir Alexander Cockburn | | Whig | Sir Alexander Cockburn | | Whig | Attorney General for England and Wales [16 2] |
| Aylesbury | 6 January 1853 [16 1] | Richard Bethell | | Whig | Richard Bethell | | Whig | Solicitor General for England and Wales [16 2] |
| Lichfield | 5 January 1853 [16 1] | Lord Alfred Paget | | Whig | Lord Alfred Paget | | Whig | Chief Equerry and Clerk Marshal [16 2] |
| Halifax | 5 January 1853 | Charles Wood | | Whig | Charles Wood | | Whig | President of the Board of Control [16 2] |
| Wolverhampton | 4 January 1853 [16 1] | Charles Pelham Villiers | | Whig | Charles Pelham Villiers | | Whig | Judge Advocate General [16 2] |
| Oxford | 4 January 1853 [16 1] | William Wood | | Whig | Edward Cardwell | | Peelite | Resignation (Vice Chancellor of the High Court) |
| Marlborough | 4 January 1853 [16 1] | Lord Ernest Bruce | | Peelite | Lord Ernest Bruce | | Peelite | Vice-Chamberlain of the Household [16 2] |
| Leith Burghs | 4 January 1853 [16 1] | James Moncreiff | | Whig | James Moncreiff | | Whig | Lord Advocate [16 2] |
| Gloucester | 4 January 1853 | Maurice Berkeley | | Whig | Maurice Berkeley | | Whig | Second Sea Lord [16 2] |
| Brighton | 4 January 1853 [16 1] | Lord Alfred Hervey | | Peelite | Lord Alfred Hervey | | Peelite | Junior Lord of the Treasury [16 2] |
| Tiverton | 3 January 1853 [16 1] | The Viscount Palmerston | | Whig | The Viscount Palmerston | | Whig | Home Secretary [16 2] |
| Carlisle | 3 January 1853 [16 1] | Matthew Talbot Baines | | Whig | Matthew Talbot Baines | | Whig | President of the Poor Law Board [16 2] |
| City of London | 3 January 1853 [16 1] | Lord John Russell | | Whig | Lord John Russell | | Whig | Foreign Secretary [16 2] |
| Scarborough | 1 January 1853 [16 1] | Earl of Mulgrave | | Whig | Earl of Mulgrave | | Whig | Treasurer of the Household [16 2] |
| Nottingham | 1 January 1853 [16 1] | Edward Strutt | | Whig | Edward Strutt | | Whig | Chancellor of the Duchy of Lancaster [16 2] |
| Morpeth | 1 January 1853 [16 1] | Edward Granville George Howard | | Whig | Sir George Grey | | Whig | Resignation |
| Hertford | 1 January 1853 [16 1] | William Cowper | | Whig | William Cowper | | Whig | Civil Lord of the Admiralty [16 2] |
| Carlisle | 1 January 1853 [16 1] | Sir James Graham | | Peelite | Sir James Graham | | Peelite | First Lord of the Admiralty [16 2] |
| Southwark | 1 January 1853 [16 1] | Sir William Molesworth | | Radical | Sir William Molesworth | | Radical | First Commissioner of Works [16 2] |
| Merthyr Tydfil | 14 December 1852 [16 1] | John Josiah Guest | | Whig | Henry Bruce | | Whig | Death |
| Lisburn | 11 December 1852 | James Emerson Tennent | | Conservative | Roger Johnson Smyth | | Peelite | Resignation |
| Peterborough | 6 December 1852 | Richard Watson | | Whig | George Hammond Whalley | | Whig | Death |
| Bury St Edmunds | 4 December 1852 | John Stuart | | Conservative | James Henry Porteous Oakes | | Conservative | Resignation (Vice Chancellor) |
| Oldham | 3 December 1852 | John Duncuft | | Conservative | William Johnson Fox | | Whig | Death |
| City Durham | 3 December 1852 | Thomas Colpitts Granger | | Whig | Lord Adolphus Vane | | Conservative | Death |
| Abingdon | 3 December 1852 | James Caulfeild | | Whig | Lord Norreys | | Whig | Death |
|
| By-election | Date | Former incumbent | Party | Winner | Party | Cause |
|---|
| Huntingdonshire | 11 June 1852 [15 1] | George Thornhill | | Conservative | Viscount Mandeville | | Conservative | Death |
| Sandwich | 28 May 1852 | Charles William Grenfell | | Whig | Lord Charles Clinton | | Conservative | Resignation in order to contest Windsor |
| Windsor | 22 May 1852 | George Alexander Reid | | Conservative | Charles William Grenfell | | Whig | Death |
| Perth | 15 May 1852 | Fox Maule | | Whig | Arthur Kinnaird | | Whig | Succession to a peerage |
| Carmarthenshire | 13 May 1852 [15 1] | George Rice-Trevor | | Conservative | David Jones | | Conservative | Succession to a peerage |
| Harwich | 8 May 1852 [15 1] | Fitzroy Kelly | | Conservative | Isaac Butt | | Conservative | Resignation in order to contest East Suffolk |
| East Suffolk | 1 May 1852 [15 1] | The Lord Rendlesham | | Conservative | Fitzroy Kelly | | Conservative | Death |
| Worcester | 28 April 1852 [15 1] | Francis Rufford | | Conservative | William Laslett | | Whig | Resignation |
| Tavistock | 28 April 1852 | John Salusbury-Trelawny | | Whig | Samuel Carter | | Whig | Seeks re-election due to opposition from local party members |
| Harwich | 10 April 1852 [15 1] | Robert Wigram Crawford | | Whig | Fitzroy Kelly | | Conservative | Void By-election |
| Monmouth Boroughs | 3 April 1852 | Reginald James Blewitt | | Whig | Crawshay Bailey | | Conservative | Resignation |
| Dungannon | 24 March 1852 [15 1] | William Stuart Knox | | Conservative | William Stuart Knox | | Conservative | Parliamentary Groom in Waiting [15 2] |
| South Shropshire | 23 March 1852 [15 1] | Viscount Newport | | Conservative | Viscount Newport | | Conservative | Vice-Chamberlain of the Household [15 2] |
| County Cork | 22 March 1852 | Maurice Power | | Irish Repeal | Vincent Scully | | Irish Repeal | Resignation (Governor of St. Lucia) |
| Coleraine | 22 March 1852 [15 1] [15 3] | John Boyd | | Conservative | Lord Naas | | Conservative | Resignation to provide a seat for Lord Naas |
| East Retford | 19 March 1852 [15 1] | The Viscount Galway | | Conservative | The Viscount Galway | | Conservative | Lord-in-waiting [15 2] |
| County Londonderry | 13 March 1852 [15 1] | Thomas Bateson | | Conservative | Thomas Bateson | | Conservative | Junior Lord of the Treasury [15 2] |
| North Lincolnshire | 13 March 1852 [15 1] | Robert Adam Christopher | | Conservative | Robert Adam Christopher | | Conservative | Resignation pending appointment as Chancellor of the Duchy of Lancaster |
| Kildare | 13 March 1852 [15 1] [15 3] | Lord Naas | | Conservative | William Henry Ford Cogan | | Whig | Chief Secretary for Ireland [15 2] |
| Tyrone | 12 March 1852 [15 1] | Lord Claud Hamilton | | Conservative | Lord Claud Hamilton | | Conservative | Treasurer of the Household [15 2] |
| South Lincolnshire | 12 March 1852 [15 1] | Sir John Trollope | | Conservative | Sir John Trollope | | Conservative | President of the Poor Law Board [15 2] |
| Buckinghamshire | 12 March 1852 [15 1] | Benjamin Disraeli | | Conservative | Benjamin Disraeli | | Conservative | Chancellor of the Exchequer [15 2] |
| Oxfordshire | 10 March 1852 [15 1] | Joseph Warner Henley | | Conservative | Joseph Warner Henley | | Conservative | President of the Board of Trade [15 2] |
| East Riding of Yorkshire | 9 March 1852 [15 1] | Arthur Duncombe | | Conservative | Arthur Duncombe | | Conservative | Fourth Naval Lord [15 2] |
| North Essex | 9 March 1852 [15 1] | William Beresford | | Conservative | William Beresford | | Conservative | Secretary at War [15 2] |
| Enniskillen | 9 March 1852 | James Whiteside | | Conservative | James Whiteside | | Conservative | Solicitor-General for Ireland [15 2] |
| Dublin University | 9 March 1852 [15 1] | Joseph Napier | | Conservative | Joseph Napier | | Conservative | Attorney-General for Ireland [15 2] |
| Dorset | 9 March 1852 [15 1] | George Bankes | | Conservative | George Bankes | | Conservative | Judge Advocate General [15 2] |
| Portarlington | 8 March 1852 [15 1] | Francis Plunkett Dunne | | Conservative | Francis Plunkett Dunne | | Conservative | Clerk of the Ordnance [15 2] |
| Stamford | 6 March 1852 [15 1] | John Charles Herries | | Conservative | John Charles Herries | | Conservative | President of the Board of Control [15 2] |
| Midhurst | 5 March 1852 [15 1] | Spencer Horatio Walpole | | Conservative | Spencer Horatio Walpole | | Conservative | Home Secretary [15 2] |
| Buckingham | 5 March 1852 [15 1] | Marquess of Chandos | | Conservative | Marquess of Chandos | | Conservative | Junior Lord of the Treasury [15 2] |
| Abingdon | 5 March 1852 [15 1] | Sir Frederic Thesiger | | Conservative | Sir Frederic Thesiger | | Conservative | Attorney General for England and Wales [15 2] |
| Droitwich | 4 March 1852 [15 1] | Sir John Pakington | | Conservative | Sir John Pakington | | Conservative | Secretary of State for War and the Colonies [15 2] |
| Colchester | 4 March 1852 [15 1] | Lord John Manners | | Conservative | Lord John Manners | | Conservative | First Commissioner of Works [15 2] |
| Chichester | 4 March 1852 [15 1] | Lord Henry Lennox | | Conservative | Lord Henry Lennox | | Conservative | Junior Lord of the Treasury [15 2] |
| Wenlock | 3 March 1852 [15 1] | George Weld-Forester | | Conservative | George Weld-Forester | | Conservative | Comptroller of the Household [15 2] |
| East Kent | 16 February 1852 | John Pemberton Plumptre | | Conservative | Sir Brook Bridges | | Conservative | Resignation |
| Kinsale | 12 February 1852 [15 1] | Benjamin Hawes | | Whig | John Isaac Heard | | Whig | Resignation |
| Northampton | 11 February 1852 | Robert Vernon Smith | | Whig | Robert Vernon Smith | | Whig | Secretary at War [15 2] |
| Greenwich | 11 February 1852 | James Whitley Deans Dundas | | Whig | Houston Stewart | | Whig | Resignation |
| East Retford | 11 February 1852 [15 1] | Arthur Duncombe | | Conservative | William Ernest Duncombe | | Conservative | Resignation in order to contest East Riding of Yorkshire |
| Perth | 9 February 1852 [15 1] | Fox Maule | | Whig | Fox Maule | | Whig | President of the Board of Control [15 2] |
| Lisburn | 5 January 1852 [15 1] | Horace Beauchamp Seymour | | Peelite | James Emerson Tennent | | Conservative | Death |
| Bradford | 21 October 1851 [15 1] | Robert Milligan | | Whig | William Busfeild | | Whig | Death |
| East Riding of Yorkshire | 7 October 1851 [15 1] | Henry Broadley | | Conservative | Arthur Duncombe | | Conservative | Death |
| Downpatrick | 8 August 1851 [15 1] | Richard Ker | | Peelite | Charles Hardinge | | Conservative | Resignation |
| Limerick City | 1 August 1851 [15 1] | John O'Connell | | Irish Repeal | Earl of Arundel | | Ind. Whig [6] | Resignation |
| Scarborough | 19 July 1851 | Earl of Mulgrave | | Whig | George Frederick Young | | Conservative | Comptroller of the Household [15 2] |
| Arundel | 16 July 1851 [15 1] | Earl of Arundel | | Whig | Edward Strutt | | Whig | Resignation in order to contest Limerick City |
| Knaresborough | 12 July 1851 | William Lascelles | | Whig | Thomas Collins | | Conservative | Death |
| Greenwich | 28 June 1851 | Edward George Barnard | | Whig | David Salomons | | Whig | Death |
| Bath | 25 June 1851 | Lord Ashley | | Conservative | George Treweeke Scobell | | Whig | Succession to a peerage |
| Clackmannanshire and Kinross-shire | 9 June 1851 | Sir William Morison | | Whig | James Johnstone | | Whig | Death |
| Argyllshire | 6 June 1851 [15 1] | Duncan McNeill | | Conservative | Sir Archibald Islay Campbell | | Conservative | Resignation (Senator of the College of Justice) |
| Newry | 30 May 1851 [15 1] | Viscount Newry | | Peelite | Edmund Gilling Hallewell | | Conservative | Death |
| Isle of Wight | 29 May 1851 | John Simeon | | Whig | Edward Dawes | | Whig | Resignation |
| Harwich | 28 May 1851 | Henry Thoby Prinsep | | Conservative | Robert Wigram Crawford | | Whig | Void By-Election |
| Cork City | 23 April 1851 [15 1] | William Trant Fagan | | Irish Repeal | Francis Murphy | | Whig | Resignation |
| Boston | 22 April 1851 | Dudley Pelham | | Whig | James William Freshfield | | Conservative | Death |
| Longford | 21 April 1851 | Samuel Wensley Blackall | | Irish Repeal | Richard More O'Ferrall | | Whig | Resignation (Governor of Dominica) |
| Leith Burghs | 14 April 1851 [15 1] | Andrew Rutherfurd | | Whig | James Moncreiff | | Whig | Resignation (Judge of the Court of Session) |
| Enniskillen | 12 April 1851 | Henry Arthur Cole | | Conservative | James Whiteside | | Conservative | Resignation |
| Aylesbury | 11 April 1851 | Frederick Calvert | | Whig | Richard Bethell | | Whig | Void By-Election |
| West Somerset | 10 April 1851 [15 1] | Sir Alexander Hood | | Conservative | William Gore-Langton | | Conservative | Death |
| Coventry | 8 April 1851 | George James Turner | | Conservative | Charles Ponsonby | | Whig | Resignation (Vice Chancellor) |
| Oxford | 3 April 1851 [15 1] | William Page Wood | | Whig | William Page Wood | | Whig | Solicitor General for England and Wales [15 2] |
| Southampton | 2 April 1851 [15 1] | Alexander Cockburn | | Whig | Alexander Cockburn | | Whig | Attorney General for England and Wales [15 2] |
| Devonport | 2 April 1851 [15 1] | John Romilly | | Whig | John Romilly | | Whig | Master of the Rolls [15 2] |
| Dungarvan | 22 March 1851 | Richard Lalor Sheil | | Whig | Charles Ponsonby | | Whig | Resignation (Minister to Tuscany) |
| Thirsk | 21 March 1851 [15 1] | John Bell | | Conservative | Sir William Payne-Gallwey | | Conservative | Death |
| Harwich | 5 March 1851 | Sir John Hobhouse | | Whig | Henry Thoby Prinsep | | Conservative | Resignation and elevation to the peerage |
| Glamorganshire | 25 February 1851 [15 1] | The Earl of Dunraven | | Conservative | Sir George Tyler | | Conservative | Resignation |
| Bedfordshire | 24 February 1851 | Viscount Alford | | Conservative | Richard Gilpin | | Conservative | Death |
| North Staffordshire | 22 February 1851 [15 1] | Viscount Brackley | | Conservative | Sir Smith Child | | Conservative | Resignation |
| South Nottinghamshire | 17 February 1851 | Robert Bromley | | Conservative | William Hodgson Barrow | | Conservative | Death |
| Falkirk Burghs | 14 February 1851 | Earl of Lincoln | | Conservative | James Baird | | Conservative | Succession to a peerage |
| Dungannon | 14 February 1851 [15 1] | Viscount Northland | | Conservative | William Stuart Knox | | Conservative | Resignation |
| Pontefract | 13 February 1851 | Samuel Martin | | Whig | Beilby Lawley | | Whig | Resignation (Baron of the Exchequer) |
| Windsor | 10 February 1851 [15 1] | John Hatchell | | Whig | John Hatchell | | Whig | Attorney-General for Ireland [15 2] |
| Aylesbury | 27 December 1850 | The Lord Nugent | | Whig | Frederick Calvert | | Whig | Death |
| St Albans | 24 December 1850 [15 4] | Alexander Raphael | | Whig | Jacob Bell | | Whig | Death |
| County Limerick | 14 December 1850 | Samuel Dickson | | Whig | Wyndham Goold | | Whig | Death |
| Herefordshire | 18 October 1850 [15 1] | Joseph Bailey | | Conservative | Thomas William Booker-Blakemore | | Conservative | Death |
| Montgomeryshire | 11 October 1850 [15 1] | Charles Williams-Wynn | | Conservative | Herbert Williams-Wynn | | Conservative | Death |
| Cambridge University | 4 October 1850 [15 1] | Charles Law | | Conservative | Loftus Wigram | | Conservative | Death |
| Poole | 24 September 1850 | George Richard Robinson | | Conservative | Henry Danby Seymour | | Whig | Death |
| Lambeth | 7 August 1850 | Charles Pearson | | Whig | William Williams | | Whig | Resignation |
| Dungannon | 3 August 1850 [15 1] | Viscount Northland | | Conservative | Viscount Northland | | Conservative | Resigned seat and was re-elected without his knowledge or consent |
| Mayo | 29 July 1850 [15 1] | Robert Dillon Browne | | Irish Repeal | George Gore Ousley Higgins | | Whig | Death |
| Chester | 22 July 1850 [15 1] | John Jervis | | Whig | William Owen Stanley | | Whig | Resignation |
| Tamworth | 19 July 1850 [15 1] | Sir Robert Peel | | Peelite | Sir Robert Peel | | Peelite | Death |
| Southampton | 17 July 1850 [15 1] | Alexander Cockburn | | Whig | Alexander Cockburn | | Whig | Solicitor General for England and Wales [15 2] |
| Devonport | 17 July 1850 [15 1] | Sir John Romilly | | Whig | Sir John Romilly | | Whig | Attorney General for England and Wales [15 2] |
| Lymington | 30 April 1850 | George Keppel | | Whig | Edward John Hutchins | | Whig | Resignation |
| Totnes | 30 March 1850 [15 1] | Lord Seymour | | Whig | Lord Seymour | | Whig | First Commissioner of Woods and Forests [15 2] |
| County Sligo | 12 March 1850 [15 1] | John Ffolliott | | Conservative | Sir Robert Gore-Booth | | Conservative | Resignation |
| Canterbury | 4 March 1850 [15 1] | Albert Denison | | Whig | Frederick Romilly | | Whig | Resignation and elevation to the peerage |
| Kirkcudbrightshire | 20 February 1850 [15 1] | Thomas Maitland | | Whig | John Mackie | | Whig | Resignation (Judge of the Court of Session) |
| Colchester | 9 February 1850 [15 1] | George Henry Smyth | | Conservative | Lord John Manners | | Conservative | Resignation |
| Windsor | 6 February 1850 [15 1] | Lord John Hay | | Whig | John Hatchell | | Whig | Resignation |
| New Shoreham | 28 December 1849 [15 1] | Charles Goring | | Conservative | Lord Alexander Gordon-Lennox | | Conservative | Death |
| Cork City | 14 November 1849 | Daniel Callaghan | | Irish Repeal | James Charles Chatterton | | Conservative | Death |
| West Surrey | 27 September 1849 | William Denison | | Whig | William John Evelyn | | Conservative | Death |
| Kidderminster | 5 September 1849 | Richard Godson | | Peelite | John Best | | Peelite | Death |
| Reading | 8 August 1849 | Thomas Noon Talfourd | | Whig | Viscount Chelsea | | Conservative | Resignation (Puisne Judge of the Court of Common Pleas) |
| Boston | 2 August 1849 | Sir James Duke | | Whig | Dudley Pelham | | Whig | Resignation in order to contest City of London |
| City of London | 27 July 1849 [15 1] | James Pattison | | Whig | Sir James Duke | | Whig | Death |
| City of London | 4 July 1849 | Lionel de Rothschild | | Whig | Lionel de Rothschild | | Whig | Seeks re-election following the rejection of the Jewish Disabilities Bill |
| South Warwickshire | 7 June 1849 [15 1] | Evelyn Shirley | | Conservative | Lord Guernsey | | Conservative | Resignation |
| Sutherland | 5 June 1849 [15 1] | Sir David Dundas | | Whig | Sir David Dundas | | Whig | Judge Advocate General [15 2] |
| County Limerick | 1 June 1849 [15 1] | William Smith O'Brien | | Irish Confederate | Samuel Dickson | | Whig | Disqualification (conviction for high treason) |
| Sheffield | 3 May 1849 [15 1] | Henry George Ward | | Whig | John Arthur Roebuck | | Ind. Whig [7] [8] | Resignation |
| South Nottinghamshire | 17 April 1849 [15 1] | Lancelot Rolleston | | Conservative | Robert Bromley | | Conservative | Resignation |
| North Hampshire | 6 April 1849 | Sir William Heathcote | | Conservative | Melville Portal | | Conservative | Resignation |
| South Derbyshire | 23 March 1849 [15 1] | Edward Miller Mundy | | Conservative | William Mundy | | Conservative | Death |
| Donegal | 20 February 1849 [15 1] | Edward Michael Conolly | | Conservative | Thomas Conolly | | Conservative | Death |
| South Staffordshire | 19 February 1849 [15 1] | Viscount Ingestre | | Conservative | Viscount Lewisham | | Conservative | Succession to a peerage |
| South Devon | 13 February 1849 [15 1] | Lord Courtenay | | Conservative | Sir Ralph Lopes | | Conservative | Resignation |
| Cardigan Boroughs | 12 February 1849 | Pryse Pryse | | Whig | Pryse Loveden | | Whig | Death |
| Bolton | 9 February 1849 | John Bowring | | Whig | Joshua Walmsley | | Whig | Resignation |
| Kingston upon Hull | 7 February 1849 [15 1] | Matthew Talbot Baines | | Whig | Matthew Talbot Baines | | Whig | President of the Poor Law Board [15 2] |
| Portsmouth | 6 February 1849 [15 1] | Francis Baring | | Whig | Francis Baring | | Whig | First Lord of the Admiralty [15 2] |
| Leominster | 6 February 1849 [15 1] | Henry Barkly | | Conservative | Frederick Peel | | Conservative | Resignation (Governor of British Guiana) |
| Truro | 11 January 1849 | Edmund Turner | | Whig | Humphrey Willyams | | Whig | Death |
| Liskeard | 3 January 1849 [15 1] | Charles Buller | | Whig | Richard Budden Crowder | | Whig | Death |
| King's Lynn | 22 December 1848 [15 1] | Lord George Bentinck | | Conservative | Edward Stanley | | Conservative | Death |
| West Riding of Yorkshire | 11 December 1848 | Viscount Morpeth | | Whig | Edmund Beckett | | Conservative | Succession to a peerage |
| Bolton | 12 September 1848 [15 1] | William Bolling | | Conservative | Stephen Blair | | Conservative | Death |
| Cheltenham | 4 September 1848 | Craven Berkeley | | Whig | Grenville Berkeley | | Whig | Void election |
| Leicester | 2 September 1848 [15 1] | Joshua Walmsley | | Whig | John Ellis | | Whig | Void election |
| Richard Gardner | | Whig | Richard Harris | | Whig | Void election |
| Derby | 2 September 1848 | Frederick Leveson-Gower | | Whig | Michael Thomas Bass | | Whig | Void election |
| Edward Strutt | | Whig | Lawrence Heyworth | | Whig | Void election |
| Thetford | 8 August 1848 [15 1] | Bingham Baring | | Conservative | Francis Baring | | Conservative | Succession to a peerage |
| Sligo Borough | 15 July 1848 | Charles Towneley | | Whig | John Patrick Somers | | Irish Repeal | Void By-Election |
| Great Yarmouth | 8 July 1848 | Lord Arthur Lennox | | Conservative | Joseph Sandars | | Conservative | Void election |
| Octavius Coope | | Conservative | Charles Rumbold | | Whig | Void election |
| Cheltenham | 29 June 1848 | Willoughby Jones | | Conservative | Craven Berkeley | | Whig | Void election |
| Horsham | 28 June 1848 | John Jervis | | Whig | William Vesey-FitzGerald | | Conservative | Void election |
| William Vesey-FitzGerald | | Conservative | Lord Edward Howard | | Whig | By-election result reversed on petition |
| North Cheshire | 8 June 1848 | Edward Stanley | | Whig | George Legh | | Conservative | Elevation to the peerage |
| York | 24 May 1848 | Henry Galgacus Redhead Yorke | | Whig | William Milner | | Whig | Death |
| Cirencester | 24 May 1848 | William Cripps | | Conservative | Joseph Randolph Mullings | | Conservative | Death |
| Wicklow | 27 April 1848 | William Acton | | Conservative | Ralph Howard | | Whig | Resignation |
| Bewdley | 18 April 1848 | Thomas James Ireland | | Conservative | Viscount Mandeville | | Conservative | Void election |
| Sligo Borough | 11 April 1848 | John Patrick Somers | | Irish Repeal | Charles Towneley | | Whig | Void election |
| Rye | 6 April 1848 [15 1] | Herbert Mascall Curteis | | Whig | Herbert Mascall Curteis | | Whig | Void By-Election |
| Devonport | 3 April 1848 [15 1] | John Romilly | | Whig | John Romilly | | Whig | Solicitor General for England and Wales [15 2] |
| Harwich | 1 April 1848 | John Attwood | | Conservative | Sir John Hobhouse | | Whig | Void election |
| Aylesbury | 29 March 1848 | John Peter Deering | | Conservative | Quintin Dick | | Conservative | Void election |
| Monmouthshire | 24 March 1848 [15 1] | Lord Granville Somerset | | Conservative | Edward Arthur Somerset | | Conservative | Death |
| Lincoln | 16 March 1848 | Charles Seely | | Whig | Thomas Hobhouse | | Whig | Void election |
| Carlisle | 14 March 1848 | William Nicholson Hodgson | | Conservative | William Nicholson Hodgson | | Conservative | Void election |
| John Dixon | | Whig | Philip Howard | | Whig | Void election |
| Kinsale | 11 March 1848 | Richard Samuel Guinness | | Conservative | Benjamin Hawes | | Whig | Void election |
| Lancaster | 9 March 1848 | Samuel Gregson | | Whig | Robert Baynes Armstrong | | Whig | Void election |
| Waterford City | 1 March 1848 | Daniel O'Connell | | Irish Repeal | Sir Henry Barron | | Whig | Resignation |
| Devizes | 25 February 1848 [15 1] | William Heald Ludlow Bruges | | Conservative | James Bucknall Bucknall Estcourt | | Conservative | Resignation |
| Dublin University | 19 February 1848 [15 1] | Frederick Shaw | | Conservative | Joseph Napier | | Conservative | Resignation |
| North Shropshire | 16 February 1848 [15 1] | Viscount Clive | | Conservative | John Whitehall Dod | | Conservative | Succession to a peerage |
| Wells | 27 December 1847 [15 1] | William Goodenough Hayter | | Whig | William Goodenough Hayter | | Whig | Judge Advocate General [15 2] |
| Calne | 27 December 1847 [15 1] | Earl of Shelburne | | Whig | Earl of Shelburne | | Whig | Junior Lord of the Treasury [15 2] |
| Rye | 23 December 1847 [15 1] | Herbert Barrett Curteis | | Whig | Herbert Mascall Curteis | | Whig | Death |
| Sunderland | 22 December 1847 | David Barclay | | Whig | Sir Hedworth Williamson | | Whig | Resignation |
| South Lancashire | 20 December 1847 [15 1] | Charles Pelham Villiers | | Whig | Alexander Henry | | Whig | Double election, chose to sit for Wolverhampton |
| Tamworth | 18 December 1847 [15 1] | William Yates Peel | | Conservative | John Townshend | | Whig | Resignation |
| Kilkenny City | 18 December 1847 [15 1] | John O'Connell | | Irish Repeal | Michael Sullivan | | Irish Repeal | Double election, chose to sit for Limerick City |
| Stockport | 16 December 1847 | Richard Cobden | | Radical | James Kershaw | | Whig | Double election, chose to sit for the West Riding of Yorkshire |
| Weymouth and Melcombe Regis | 15 December 1847 [15 1] | William Dougal Christie | | Whig | Frederick Child Villiers | | Conservative | Resignation (to avoid election petition) |
| Newcastle-under-Lyme | 15 December 1847 | Samuel Christy | | Conservative | Samuel Christy | | Conservative | Seeks re-election due to his firm holding a government contract |
| Edinburgh | 15 December 1847 [15 1] | Charles Cowan | | Whig | Charles Cowan | | Whig | Disqualification (held government contract) |
| Liskeard | 14 December 1847 [15 1] | Charles Buller | | Whig | Charles Buller | | Whig | President of the Poor Law Board [15 2] |
|