Sapronosis

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Colonies of the bacterial sapronosis Legionella pneumophila LegionellaPneumophila Kolonie.jpg
Colonies of the bacterial sapronosis Legionella pneumophila

A sapronosis is an infectious disease caused by an organism that is able to live and reproduce in the soil or an other abiotic environment, and infects a living host directly from that environment. One widely-known example of a sapronosis is Legionnaire's disease. [1] Approximately a third of all known disease organisms are sapronoses. [1] Almost all fungal infections are sapronoses, [1] but there are no known sapronotic viruses. [2]

Contents

Occupation often plays a role in sapronoses: people working with the soil, such as farmers or gardeners, are often at particularly high risk. [3] Sporotrichosis, a fungal sapronosis, is for example sometimes known as "rose handler's disease". [4]

Sapronoses pose unique public health challenges. Because they can persist in the environment outside of any living host, they are difficult to control or eradicate. [5] Their spread is also not subject to threshold host density. [1] Sapronotic outbreaks are typically caused by a common source material, can be stopped by removing that material. [6] For example, an outbreak of sporotrichosis that affected more than 3000 South African miners was stopped by removing wood in which the fungus was living. [6]

Terminology and classification

The term "sapronosis" was coined by the Russian microbiologist Vasiliy Ilyich Terskikh in 1958, who contested the then-widespread idea that pathogenic bacteria could not persist in the environment outside of a host. [7]

Sapronoses sometimes serve as one part of the three-part classification of infectious diseases; the other two parts are anthroponoses (spread mostly from human to human) and zoonoses (spread mostly from animals to humans). [2] In contrast to those, the primary reservoir of a sapronosis is in the soil. [2] Sapronoses are therefore sometimes distinguished from environmental pathogens, also called "saprozoonoses", which have one part of their life cycle in the soil and one part in an animal host. [6]

Typical examples of sapronotic agents are fungal such as coccidioidomycosis, histoplasmosis, aspergillosis, cryptococcosis, Microsporum gypseum. Some can be bacterial from the sporulating clostridium and bacillus to Rhodococcus equi, Burkholderia pseudomallei, Listeria, Erysipelothrix, Yersinia pseudotuberculosis, legionellosis, Pontiac fever, and nontuberculous mycobacterioses. Other sapronotic agents are amebic as in primary amebic meningoencephalitis. Yet again, difficulties in classification arise in the case of sporulating bacteria whose infectious spores are only produced after a significant period of inactive vegetative growth within an abiotic environment, yet this is still considered a case of sapronoses. [2]

See also

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A human pathogen is a pathogen that causes disease in humans.

<span class="mw-page-title-main">Zoonosis</span> Disease that can be transmitted from other species to humans

A zoonosis or zoonotic disease is an infectious disease of humans caused by a pathogen that can jump from a non-human to a human and vice versa.

<span class="mw-page-title-main">Infection</span> Invasion of an organisms body by pathogenic agents

An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection.

<span class="mw-page-title-main">Epidemic</span> Rapid spread of disease affecting a large number of people in a short time

An epidemic is the rapid spread of disease to a large number of hosts in a given population within a short period of time. For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic.

<span class="mw-page-title-main">Plant pathology</span> Scientific study of plant diseases

Plant pathology is the scientific study of diseases in plants caused by pathogens and environmental conditions. Organisms that cause infectious disease include fungi, oomycetes, bacteria, viruses, viroids, virus-like organisms, phytoplasmas, protozoa, nematodes and parasitic plants. Not included are ectoparasites like insects, mites, vertebrate, or other pests that affect plant health by eating plant tissues and causing injury that may admit plant pathogens. Plant pathology also involves the study of pathogen identification, disease etiology, disease cycles, economic impact, plant disease epidemiology, plant disease resistance, how plant diseases affect humans and animals, pathosystem genetics, and management of plant diseases.

In medicine, public health, and biology, transmission is the passing of a pathogen causing communicable disease from an infected host individual or group to a particular individual or group, regardless of whether the other individual was previously infected. The term strictly refers to the transmission of microorganisms directly from one individual to another by one or more of the following means:

Nontuberculous mycobacteria (NTM), also known as environmental mycobacteria, atypical mycobacteria and mycobacteria other than tuberculosis (MOTT), are mycobacteria which do not cause tuberculosis or leprosy. NTM do cause pulmonary diseases that resemble tuberculosis. Mycobacteriosis is any of these illnesses, usually meant to exclude tuberculosis. They occur in many animals, including humans and are commonly found in soil and water.

<span class="mw-page-title-main">Natural reservoir</span> Type of population in infectious disease ecology

In infectious disease ecology and epidemiology, a natural reservoir, also known as a disease reservoir or a reservoir of infection, is the population of organisms or the specific environment in which an infectious pathogen naturally lives and reproduces, or upon which the pathogen primarily depends for its survival. A reservoir is usually a living host of a certain species, such as an animal or a plant, inside of which a pathogen survives, often without causing disease for the reservoir itself. By some definitions a reservoir may also be an environment external to an organism, such as a volume of contaminated air or water.

<span class="mw-page-title-main">Leaf spot</span> Type of area of a leaf

A leaf spot is a limited, discoloured, diseased area of a leaf that is caused by fungal, bacterial or viral plant diseases, or by injuries from nematodes, insects, environmental factors, toxicity or herbicides. These discoloured spots or lesions often have a centre of necrosis. Symptoms can overlap across causal agents, however differing signs and symptoms of certain pathogens can lead to the diagnosis of the type of leaf spot disease. Prolonged wet and humid conditions promote leaf spot disease and most pathogens are spread by wind, splashing rain or irrigation that carry the disease to other leaves.

<span class="mw-page-title-main">Sporotrichosis</span> Medical condition

Sporotrichosis, also known as rose handler's disease, is a fungal infection that may be localised to skin, lungs, bone and joint, or become systemic. It presents with firm painless nodules that later ulcerate. Following initial exposure to Sporothrix schenckii, the disease typically progresses over a period of a week to several months. Serious complications may develop in people who have a weakened immune system.

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<i>Sporothrix schenckii</i> Species of fungus

Sporothrix schenckii, a fungus that can be found worldwide in the environment, is named for medical student Benjamin Schenck, who in 1896 was the first to isolate it from a human specimen. The species is present in soil as well as in and on living and decomposing plant material such as peat moss. It can infect humans as well as animals and is the causative agent of sporotrichosis, commonly known as "rose handler's disease." The most common route of infection is the introduction of spores to the body through a cut or puncture wound in the skin. Infection commonly occurs in otherwise healthy individuals but is rarely life-threatening and can be treated with antifungals. In the environment it is found growing as filamentous hyphae. In host tissue it is found as a yeast. The transition between the hyphal and yeast forms is temperature dependent making S. schenckii a thermally dimorphic fungus.

<i>Aspergillus terreus</i> Species of fungus

Aspergillus terreus, also known as Aspergillus terrestris, is a fungus (mold) found worldwide in soil. Although thought to be strictly asexual until recently, A. terreus is now known to be capable of sexual reproduction. This saprotrophic fungus is prevalent in warmer climates such as tropical and subtropical regions. Aside from being located in soil, A. terreus has also been found in habitats such as decomposing vegetation and dust. A. terreus is commonly used in industry to produce important organic acids, such as itaconic acid and cis-aconitic acid, as well as enzymes, like xylanase. It was also the initial source for the drug mevinolin (lovastatin), a drug for lowering serum cholesterol.

<i>Rhizopus microsporus</i> Species of fungus

Rhizopus microsporus is a fungal plant pathogen infecting maize, sunflower, and rice.

A reverse zoonosis, also known as a zooanthroponosis or anthroponosis, is a pathogen reservoired in humans that is capable of being transmitted to non-human animals.

In biology, a pathogen, in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ.

<span class="mw-page-title-main">One Health Model</span> Concept of interaction between all components of the global ecosystem determining its health

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<span class="mw-page-title-main">Feline zoonosis</span> Medical condition

A feline zoonosis is a viral, bacterial, fungal, protozoan, nematode or arthropod infection that can be transmitted to humans from the domesticated cat, Felis catus. Some of these diseases are reemerging and newly emerging infections or infestations caused by zoonotic pathogens transmitted by cats. In some instances, the cat can display symptoms of infection and sometimes the cat remains asymptomatic. There can be serious illnesses and clinical manifestations in people who become infected. This is dependent on the immune status and age of the person. Those who live in close association with cats are more prone to these infections. But those that do not keep cats as pets are also able to acquire these infections because of the transmission can be from cat feces and the parasites that leave their bodies.

Laura H. Kahn is a native Californian. She is an author, lecturer, a general internist physician, and a research scholar with the Program on Science and Global Security at the Woodrow Wilson School of Public and International Affairs at Princeton University in New Jersey. She is the co-founder, of One Health Initiative. She is an online columnist for the Bulletin of the Atomic Scientists. She is an expert advisor and author in the field of zoonosis. Zoonosis is the study of infectious diseases where cross-species illnesses that are caused by bacteria, viruses, or parasites spread from non-human animals to humans. She is the author of Who's in Charge? Leadership During Epidemics, Bioterror Attacks, and Other Public Health Crises

Sporothrix brasiliensis is a fungus that is commonly found in soil. It is an emerging fungal pathogen that is causing disease in humans and cats mainly in Brazil and other countries in South America.

References

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