Vector control is any method to limit or eradicate the mammals, birds, insects or other arthropods (here collectively called "vectors") which transmit disease pathogens. The most frequent type of vector control is mosquito control using a variety of strategies. Several of the "neglected tropical diseases" are spread by such vectors.
For diseases where there is no effective cure, such as Zika virus, West Nile fever and Dengue fever, vector control remains the only way to protect human populations.[ citation needed ]
However, even for vector-borne diseases with effective treatments the high cost of treatment remains a huge barrier to large amounts of developing world populations. Despite being treatable, malaria has by far the greatest impact on human health from vectors. In Africa, a child dies every minute of malaria; this is a reduction of more than 50% since 2000 due to vector control. [1] In countries where malaria is well established the World Health Organization estimates countries lose 1.3% annual economic income due to the disease. [2] Both prevention through vector control and treatment are needed to protect populations.[ citation needed ]
As the impacts of disease and virus are devastating, the need to control the vectors in which they carried is prioritized. Vector control in many developing countries can have tremendous impacts as it reduces mortality rates, especially among infants. [3] Because of the high movement of the population, disease spread is also a greater issue in these areas. [4]
As many vector control methods are effective against multiple diseases, they can be integrated together to combat multiple diseases at once. [5] The World Health Organization therefore recommends "Integrated Vector Management" as the process for developing and implementing strategies for vector control. [6]
Vector control focuses on utilizing preventive methods to control or eliminate vector populations. Common preventive measures are:
Removing or reducing areas where vectors can easily breed can help limit their growth. For example, stagnant water removal, destruction of old tires and cans which serve as mosquito breeding environments, and good management of used water can reduce areas of excessive vector incidence.[ citation needed ]
Further examples of environmental control is by reducing the prevalence of open defecation or improving the designs and maintenance of pit latrines. This can reduce the incidence of flies acting as vectors to spread diseases via their contact with feces of infected people.[ citation needed ]
Limiting exposure to insects or animals that are known disease vectors can reduce infection risks significantly. For example, bed nets, window screens on homes, or protective clothing can help reduce the likelihood of contact with vectors. To be effective this requires education and promotion of methods among the population to raise the awareness of vector threats.
Insecticides, larvicides, rodenticides, Lethal ovitraps and repellents can be used to control vectors. For example, larvicides can be used in mosquito breeding zones; insecticides can be applied to house walls or bed nets, and use of personal repellents can reduce incidence of insect bites and thus infection. The use of pesticides for vector control is promoted by the World Health Organization (WHO) and has proven to be highly effective. [7]
The use of natural vector predators, such as bacterial toxins or botanical compounds, can help control vector populations. Using fish that eat mosquito larvae, the use of Catfish to eat up mosquito larvae in ponds can eradicate the mosquito population, or reducing breeding rates by introducing sterilized male tsetse flies have been shown to control vector populations and reduce infection risks. [8]
In the United States, cities or special districts are responsible for vector control. For example, in California, the Greater Los Angeles County Vector Control District is a special district set up by the state to oversee vector control in multiple cities. [9]
Dichlorodiphenyltrichloroethane, commonly known as DDT, is a colorless, tasteless, and almost odorless crystalline chemical compound, an organochloride. Originally developed as an insecticide, it became infamous for its environmental impacts. DDT was first synthesized in 1874 by the Austrian chemist Othmar Zeidler. DDT's insecticidal action was discovered by the Swiss chemist Paul Hermann Müller in 1939. DDT was used in the second half of World War II to limit the spread of the insect-borne diseases malaria and typhus among civilians and troops. Müller was awarded the Nobel Prize in Physiology or Medicine in 1948 "for his discovery of the high efficiency of DDT as a contact poison against several arthropods". The WHO's anti-malaria campaign of the 1950s and 1960s relied heavily on DDT and the results were promising, though there was a resurgence in developing countries afterwards.
Malaria is a mosquito-borne infectious disease that affects vertebrates and Anopheles mosquitoes. Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected Anopheles mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquito vector is itself harmed by Plasmodium infections, causing reduced lifespan.
Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains—particularly in the back—and headaches. Symptoms typically improve within five days. In about 15% of people, within a day of improving the fever comes back, abdominal pain occurs, and liver damage begins causing yellow skin. If this occurs, the risk of bleeding and kidney problems is increased.
Arbovirus is an informal name for any virus that is transmitted by arthropod vectors. The term arbovirus is a portmanteau word. Tibovirus is sometimes used to more specifically describe viruses transmitted by ticks, a superorder within the arthropods. Arboviruses can affect both animals and plants. In humans, symptoms of arbovirus infection generally occur 3–15 days after exposure to the virus and last three or four days. The most common clinical features of infection are fever, headache, and malaise, but encephalitis and viral hemorrhagic fever may also occur.
In the United States, the National Malaria Eradication Program (NMEP) was launched in July 1947. By 1951 this federal program—with state and local participation—had reduced the incidence of malaria in the United States to the point that the program was officially ended.
Tropical diseases are diseases that are prevalent in or unique to tropical and subtropical regions. The diseases are less prevalent in temperate climates, due in part to the occurrence of a cold season, which controls the insect population by forcing hibernation. However, many were present in northern Europe and northern America in the 17th and 18th centuries before modern understanding of disease causation. The initial impetus for tropical medicine was to protect the health of colonial settlers, notably in India under the British Raj. Insects such as mosquitoes and flies are by far the most common disease carrier, or vector. These insects may carry a parasite, bacterium or virus that is infectious to humans and animals. Most often disease is transmitted by an insect bite, which causes transmission of the infectious agent through subcutaneous blood exchange. Vaccines are not available for most of the diseases listed here, and many do not have cures.
An insect repellent is a substance applied to the skin, clothing, or other surfaces to discourage insects from landing or climbing on that surface. Insect repellents help prevent and control the outbreak of insect-borne diseases such as malaria, Lyme disease, dengue fever, bubonic plague, river blindness, and West Nile fever. Pest animals commonly serving as vectors for disease include insects such as flea, fly, and mosquito; and ticks (arachnids).
A mosquito net is a type of meshed curtain that is circumferentially draped over a bed or a sleeping area to offer the sleeper barrier protection against bites and stings from mosquitos, flies, and other pest insects, and thus against the diseases they may carry. Examples of such preventable insect-borne diseases include malaria, dengue fever, yellow fever, zika virus, Chagas disease, and various forms of encephalitis, including the West Nile virus.
Mosquito control manages the population of mosquitoes to reduce their damage to human health, economies, and enjoyment. Mosquito control is a vital public-health practice throughout the world and especially in the tropics because mosquitoes spread many diseases, such as malaria and the Zika virus.
Deltamethrin is a pyrethroid ester insecticide. Deltamethrin plays a key role in controlling malaria vectors, and is used in the manufacture of long-lasting insecticidal mosquito nets; however, resistance of mosquitos and bed bugs to deltamethrin has seen a widespread increase.
Paratransgenesis is a technique that attempts to eliminate a pathogen from vector populations through transgenesis of a symbiont of the vector. The goal of this technique is to control vector-borne diseases. The first step is to identify proteins that prevent the vector species from transmitting the pathogen. The genes coding for these proteins are then introduced into the symbiont, so that they can be expressed in the vector. The final step in the strategy is to introduce these transgenic symbionts into vector populations in the wild. One use of this technique is to prevent mortality for humans from insect-borne diseases. Preventive methods and current controls against vector-borne diseases depend on insecticides, even though some mosquito breeds may be resistant to them. There are other ways to fully eliminate them. “Paratransgenesis focuses on utilizing genetically modified insect symbionts to express molecules within the vector that are deleterious to pathogens they transmit.” The acidic bacteria Asaia symbionts are beneficial in the normal development of mosquito larvae; however, it is unknown what Asais symbionts do to adult mosquitoes.
Avian malaria is a parasitic disease of birds, caused by parasite species belonging to the genera Plasmodium and Hemoproteus. The disease is transmitted by a dipteran vector including mosquitoes in the case of Plasmodium parasites and biting midges for Hemoproteus. The range of symptoms and effects of the parasite on its bird hosts is very wide, from asymptomatic cases to drastic population declines due to the disease, as is the case of the Hawaiian honeycreepers. The diversity of parasites is large, as it is estimated that there are approximately as many parasites as there are species of hosts. As research on human malaria parasites became difficult, Dr. Ross studied avian malaria parasites. Co-speciation and host switching events have contributed to the broad range of hosts that these parasites can infect, causing avian malaria to be a widespread global disease, found everywhere except Antarctica.
In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen such as a parasite or microbe, to another living organism. Agents regarded as vectors are mostly blood-sucking insects such as mosquitoes. The first major discovery of a disease vector came from Ronald Ross in 1897, who discovered the malaria pathogen when he dissected the stomach tissue of a mosquito.
Indoor residual spraying or IRS is the process of spraying the inside of dwellings with an insecticide to kill mosquitoes that spread malaria. A dilute solution of insecticide is sprayed on the inside walls of certain types of dwellings—those with walls made from porous materials such as mud or wood but not plaster as in city dwellings. Mosquitoes are killed or repelled by the spray, preventing the transmission of the disease. In 2008, 44 countries employed IRS as a malaria control strategy. Several pesticides have historically been used for IRS, the first and most well-known being DDT.
Mosquito-borne diseases or mosquito-borne illnesses are diseases caused by bacteria, viruses or parasites transmitted by mosquitoes. Nearly 700 million people contract mosquito-borne illnesses each year, resulting in more than a million deaths.
The administration of drugs to whole populations irrespective of disease status is referred to as mass drug administration (MDA) or mass dispensing.
In the United States, the National Malaria Eradication Program (NMEP) was launched in July 1947. By 1951 this federal program—with state and local participation—had reduced the incidence of malaria in the United States to the point that the program was officially ended.
Target Malaria is a not-for-profit international research consortium that aims to co-develop and share novel genetic technologies to help control malaria in Africa. The consortium brings together research institutes and universities from Africa, Europe and North America.
Quartan fever is one of the four types of malaria which can be contracted by humans.
Tom McLean is a British chemist who is currently the COO of the Innovative Vector Control Consortium.
