Small nucleolar RNA SNORA7 | |
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![]() Predicted secondary structure and sequence conservation of SNORA7 | |
Identifiers | |
Symbol | SNORA7 |
Alt. Symbols | snoACA7 |
Rfam | RF00409 |
Other data | |
RNA type | Gene; snRNA; snoRNA; H/ACA-box |
Domain(s) | Eukaryota |
GO | 0006396 0005730 |
SO | 0000594 |
PDB structures | PDBe |
In molecular biology, SNORA7 (also known as ACA7) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. [1]
Molecular biology is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions. Writing in Nature in 1961, William Astbury described molecular biology as:
...not so much a technique as an approach, an approach from the viewpoint of the so-called basic sciences with the leading idea of searching below the large-scale manifestations of classical biology for the corresponding molecular plan. It is concerned particularly with the forms of biological molecules and [...] is predominantly three-dimensional and structural – which does not mean, however, that it is merely a refinement of morphology. It must at the same time inquire into genesis and function.
Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, the C/D box snoRNAs, which are associated with methylation, and the H/ACA box snoRNAs, which are associated with pseudouridylation. SnoRNAs are commonly referred to as guide RNAs but should not be confused with the guide RNAs that direct RNA editing in trypanosomes.
Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond.
The family also contains the mouse sequence MBI-141. [2]
In molecular biology, SNORA13 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA15 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA19 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA20 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
SNORA21 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA24 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA26 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA28 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA29 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
SNORA30 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of eukaryotic cells. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA' as it 'guides' the modification process.
In molecular biology, SNORA33 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA4 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA41 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
In molecular biology, SNORA42 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
Small nucleolar RNA SNORA44 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
In molecular biology, SNORA5 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
Small nucleolar RNA SNORA58 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
Small nucleolar RNA SNORA62 (E2) belongs to the H/ACA class of snoRNAs.
In molecular biology, small nucleolar RNA SNORA10 and small nuclear RNA SNORA64 are homologous members of the H/ACA class of small nucleolar RNA (snoRNA). This family of ncRNAs involved in the maturation of ribosomal RNA. snoRNA in this family act as guides in the modification of uridines to pseudouridines. This family includes the human snoRNAs U64 and ACA10 and mouse MBI-29.
Small nucleolar RNA SNORA79 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).
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