Small nucleolar RNA SNORA7

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Small nucleolar RNA SNORA7
RF00409.jpg
Identifiers
SymbolSNORA7
Alt. SymbolssnoACA7
Rfam RF00409
Other data
RNA type Gene; snRNA; snoRNA; H/ACA-box
Domain(s) Eukaryota
GO 0006396 0005730
SO 0000594
PDB structures PDBe

In molecular biology, SNORA7 (also known as ACA7) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. [1]

Molecular biology branch of biology that deals with the molecular basis of biological activity

Molecular biology is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions. Writing in Nature in 1961, William Astbury described molecular biology as:

...not so much a technique as an approach, an approach from the viewpoint of the so-called basic sciences with the leading idea of searching below the large-scale manifestations of classical biology for the corresponding molecular plan. It is concerned particularly with the forms of biological molecules and [...] is predominantly three-dimensional and structural – which does not mean, however, that it is merely a refinement of morphology. It must at the same time inquire into genesis and function.

Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, the C/D box snoRNAs, which are associated with methylation, and the H/ACA box snoRNAs, which are associated with pseudouridylation. SnoRNAs are commonly referred to as guide RNAs but should not be confused with the guide RNAs that direct RNA editing in trypanosomes.

Uridine chemical compound

Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond.

The family also contains the mouse sequence MBI-141. [2]

Related Research Articles

Small nucleolar RNA SNORA13

In molecular biology, SNORA13 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA15

In molecular biology, SNORA15 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA19

In molecular biology, SNORA19 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA20

In molecular biology, SNORA20 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA21

SNORA21 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA24

In molecular biology, SNORA24 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA26

In molecular biology, SNORA26 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA28

In molecular biology, SNORA28 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA29

In molecular biology, SNORA29 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA30

SNORA30 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of eukaryotic cells. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA' as it 'guides' the modification process.

Small nucleolar RNA SNORA33

In molecular biology, SNORA33 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA4

In molecular biology, SNORA4 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA41

In molecular biology, SNORA41 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA42

In molecular biology, SNORA42 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA44

Small nucleolar RNA SNORA44 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.

Small nucleolar RNA SNORA5

In molecular biology, SNORA5 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.

Small nucleolar RNA SNORA58

Small nucleolar RNA SNORA58 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".

Small nucleolar RNA SNORA62

Small nucleolar RNA SNORA62 (E2) belongs to the H/ACA class of snoRNAs.

Small nucleolar RNA SNORA64/SNORA10 family

In molecular biology, small nucleolar RNA SNORA10 and small nuclear RNA SNORA64 are homologous members of the H/ACA class of small nucleolar RNA (snoRNA). This family of ncRNAs involved in the maturation of ribosomal RNA. snoRNA in this family act as guides in the modification of uridines to pseudouridines. This family includes the human snoRNAs U64 and ACA10 and mouse MBI-29.

Small nucleolar RNA SNORA79

Small nucleolar RNA SNORA79 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).

References

  1. ↑ Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC   480876 . PMID   15199136.
  2. ↑ Hüttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J (June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal. 20 (11): 2943–53. doi:10.1093/emboj/20.11.2943. PMC   125495 . PMID   11387227.
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