In molecular biology, Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, the C/D box snoRNAs, which are associated with methylation, and the H/ACA box snoRNAs, which are associated with pseudouridylation. SnoRNAs are commonly referred to as guide RNAs but should not be confused with the guide RNAs that direct RNA editing in trypanosomes.
In molecular biology, SNORD15 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, snoRNA U20 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, snoRNA U22 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, U24 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. C/D box snoRNAs have been shown to act as methylation guides for a number of RNA targets. U24 is encoded within an intron of the gene for ribosomal protein L7a in mammals, chicken and Fugu. The U76/SNORD76 snoRNA is found in an intron of the uRNA host gene (UHG) growth arrest specific 5 (GAS5) transcript gene. snoRNAs Z20 and U76 snoRNAs show clear similarity to U24.
In molecular biology, snoRNA U25 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, Small nucleolar RNA SNORD27 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U27 is encoded within the U22 snoRNA host gene (UHG) in mammals and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA. This family also contains several related snoRNAs from yeast and plants.
In molecular biology, Small nucleolar RNA SNORD28 (U28) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U28 is encoded within the U22 snoRNA host gene (UHG) in mammals and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.
In molecular biology, SNORD29 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, Small nucleolar RNA SNORD30 (U30) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U30 is encoded within the U22 snoRNA host gene (UHG) in mammals and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.
In molecular biology, Small nucleolar RNA SNORD31 (U31) is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U31 is encoded within the U22 snoRNA host gene (UHG) in mammals and is thought to act as a 2'-O-ribose methylation guide for ribosomal RNA.
In molecular biology, SNORD48 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, snoRNA U56 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, snoRNA U62 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, snoRNA U63 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
In molecular biology, SNORD77 belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of large 28S rRNA subunit at position A1521. The C/D snoRNAs U44, U47, U74, U75, U76, U78, U79, U80 and U81 share the same host gene as U77 (non-coding).
In molecular biology, SNORD78 belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit at position G4593. The snoRNAs U44, U47, U74, U75, U76, U77, U79, U80 and U81, also of the C/D family, share the same host gene with U78.
In molecular biology, snoRNA U79 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
Small Cajal body-specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) that specifically localise to the Cajal body, a nuclear organelle involved in the biogenesis of small nuclear ribonucleoproteins. ScaRNAs guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.
In molecular biology, Small Nucleolar RNA SNORD75 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
