Small nucleolar RNA snR48

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Small nucleolar RNA snR48
RF00471.jpg
Predicted secondary structure and sequence conservation of snosnR48
Identifiers
SymbolsnosnR48
Rfam RF00471
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0005730 GO:0006396
SO SO:0000593
PDB structures PDBe

In molecular biology, the snoRNA snR48 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

snR48 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. [1] [2]

snR48 was identified in yeast ( Saccharomyces cerevisiae ) by computational screening of the yeast genome. This snoRNA is predicted to guide the 2'O ribosose methylation of 28S ribosomal RNA (rRNA) residues Gm2788 and Gm2790. [3]

Related Research Articles

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Small nucleolar RNA snR60/Z15/Z230/Z193/J17

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Small nucleolar RNA snR61/Z1/Z11

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Small nucleolar RNA Z13/snr52

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Small nucleolar RNA Me28S-Gm1083

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Small nucleolar RNA R12

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Small nucleolar RNA R160

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Small nucleolar RNA R38

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Small nucleolar RNA R41

In molecular biology, Small nucleolar RNA R41 is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA R66

In molecular biology, Small nucleolar RNA R66 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA SNORD37

In molecular biology, SNORD37 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA snR53

In molecular biology,snoRNA snR53 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR53 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR53 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.

Small nucleolar RNA snR54

In molecular biology, snR54 is a non-coding RNA that is a member of the C/D class of snoRNA which contain the C box motif (UGAUGA) and D box motif (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. This snoRNA was first identified by a computational screen followed by experimental verification. This RNA guides the 2'-O-methylation of 18S rRNA. In yeast this snoRNA is found to reside in an intron of the IMD4 gene.

Small nucleolar RNA snR57

In molecular biology, snoRNA snR57 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR57 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR57 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.

Small nucleolar RNA snR64

In molecular biology, snR64 is an RNA molecule belonging to the C/D class of small nucleolar RNA (snoRNA), which contain the C (UGAUGA) and D (CUGA) box motifs. Similar to most members of the box C/D family, snR64 is conjectured to help direct site-specific 2'-O-methylation of substrate RNAs.

Small nucleolar RNA snR66

snoRNA snR66 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR66 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR66 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.

Small nucleolar RNA snR69

In molecular biology, snoRNA snR69 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR69 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR69 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.

Small nucleolar RNA snR71

In molecular biology, snoRNA snR71 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR71 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR71 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.

Small nucleolar RNA snoR9 plant

In molecular biology, snoR9 is a non-coding RNA (ncRNA) which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.

The small nucleolar RNAs (snoRNAs) represent an abundant group of small non-coding RNAs (ncRNAs) in eukaryotes. With the exception of RNase MRP, all the snoRNAs fall into two major families, box C/D and box H/ACA snoRNAs, on the basis of common sequence motifs and structural features. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense sequence to rRNAs or snRNAs. Recently, thousands of novel snoRNAs were identified from small RNA sequencing datasets in human, mouse, chicken, Ciona intestinalis, Drosophila melanogaster, Caenhorhabditis elegans and Arabidopsis thaliana using snoSeekerNGS program.

References

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  2. Kiss T (April 2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell. 109 (2): 145–8. doi: 10.1016/S0092-8674(02)00718-3 . PMID   12007400. S2CID   8968788.
  3. Lowe TM, Eddy SR (February 1999). "A computational screen for methylation guide snoRNAs in yeast". Science. 283 (5405): 1168–71. Bibcode:1999Sci...283.1168L. doi:10.1126/science.283.5405.1168. PMID   10024243.