Small nucleolar RNA Z242

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Small nucleolar RNA Z242
RF00441.jpg
Predicted secondary structure and sequence conservation of snoZ242
Identifiers
SymbolsnoZ242
Rfam RF00441
Other data
RNA type Gene; snRNA; snoRNA; CD-box
Domain(s) Eukaryota
GO GO:0006396 GO:0005730
SO SO:0001263
PDB structures PDBe

In molecular biology, Small nucleolar RNA Z242 is a non-coding RNA (ncRNA) molecule which function in the biogenesis of other small nuclear RNAs (snRNAs). This small nucleolar RNA (snoRNA) is a modifying RNA and usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.

snoRNA Z242 was identified in rice Oryza sativa , [1] and is predicted to belong to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. [2]

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In molecular biology, Small nucleolar RNA Z43 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Z43 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. Plant snoRNA Z43 was identified in a screen of Oryza sativa.

References

  1. ↑ Chen CL, Liang D, Zhou H, Zhuo M, Chen YQ, Qu LH (2003). "The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa". Nucleic Acids Res. 31 (10): 2601–13. doi:10.1093/nar/gkg373. PMC   156054 . PMID   12736310.
  2. ↑ Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002). "Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro". Molecular and Cellular Biology . 22 (19): 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMC   134041 . PMID   12215523.


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