Small nucleolar RNA SNORA62

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Small nucleolar RNA SNORA62/SNORA6 family
RF00091.jpg
Predicted secondary structure and sequence conservation of SNORA62
Identifiers
SymbolSNORA62
Alt. SymbolsE2
Rfam RF00091
Other data
RNA type Gene; snRNA; snoRNA; H/ACA-box
Domain Eukaryota
GO GO:0006396 GO:0005730
SO SO:0000594
PDB structures PDBe

In molecular biology, Small nucleolar RNA SNORA62 (E2) belongs to the H/ACA class of snoRNAs. [1]

E2 is involved in the processing of eukaryotic pre-rRNA and has regions of complementarity to 28S rRNA. [2] E2 is encoded in introns in the gene for a laminin-binding protein. [3]

This family also contains the related ACA6, M2 and MBI-136 snoRNAs. [2] [4]

References

  1. ↑ Hüttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J (June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal. 20 (11): 2943–53. doi:10.1093/emboj/20.11.2943. PMC   125495 . PMID   11387227.
  2. 1 2 Mishra RK, Eliceiri GL (May 1997). "Three small nucleolar RNAs that are involved in ribosomal RNA precursor processing". Proceedings of the National Academy of Sciences of the United States of America. 94 (10): 4972–7. Bibcode:1997PNAS...94.4972M. doi: 10.1073/pnas.94.10.4972 . PMC   24615 . PMID   9144174.
  3. ↑ Selvamurugan N, Eliceiri GL (November 1995). "The gene for human E2 small nucleolar RNA resides in an intron of a laminin-binding protein gene". Genomics. 30 (2): 400–1. PMID   8586453.
  4. ↑ Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC   480876 . PMID   15199136.
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