Small nucleolar RNA SNORD32

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Small nucleolar RNA SNORD32
RF00219.jpg
Identifiers
SymbolSNORD32
Rfam RF00219
Other data
RNA typeGene; snRNA; guide; CD-box;
PDB structures PDBe

In molecular biology, snoRNA U32 (also known as SNORD32) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

snoRNA U32 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. [1]

U32 is encoded within intron 2 of the ribosomal protein L13 gene in human and mouse [2] and is predicted to guide the 2'O-ribose methylation of both 18S ribosomal RNA (rRNA) residue G1328 and 28S rRNA residue A1511. [2] [3] U32A share the same host gene with the C/D box snoRNAs U33, U34 and U35A (RPL13A). [3]

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Small nucleolar RNA SNORD103

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Small nucleolar RNA SNORD15

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Small nucleolar RNA SNORD16

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Small nucleolar RNA SNORD20

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Small nucleolar RNA SNORD22

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Small nucleolar RNA SNORD35

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Small nucleolar RNA SNORD36

In molecular biology, snoRNA U36 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA SNORD38

In molecular biology, snoRNA U38 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA SNORD43

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Small nucleolar RNA SNORD46

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Small nucleolar RNA SNORD47

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Small nucleolar RNA SNORD49

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Small nucleolar RNA SNORD52

In molecular biology, snoRNA U52 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA SNORD56

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Small nucleolar RNA SNORD57

In molecular biology, snoRNA U57 is a member of the C/D box class of snoRNAs. This family functions to direct site-specific 2'-O-methylation of substrate RNAs.

Small nucleolar RNA SNORD58

In molecular biology, snoRNA U58 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA SNORD62

In molecular biology, snoRNA U62 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA SNORD73

In molecular biology, snoRNA U73 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

Small nucleolar RNA SNORD82

In molecular biology, snoRNA U82 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

References

  1. ↑ Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002). "Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro". Molecular and Cellular Biology . 22 (19): 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMC   134041 . PMID   12215523.
  2. 1 2 Nicoloso, M; Qu LH; Michot B; Bachellerie JP (1996). "Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs". J Mol Biol. 260 (2): 178–195. doi:10.1006/jmbi.1996.0391. PMID   8764399.
  3. 1 2 Lestrade, Laurent; Weber, Michel J. (2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research . 34 (Supplement 1: Database Issue): D158–D162. CiteSeerX   10.1.1.105.7552 . doi:10.1093/nar/gkj002. PMC   1347365 . PMID   16381836.


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