 | |
 | |
| Names | |
|---|---|
| Preferred IUPAC name (4-Amino-2-methylpyrimidin-5-yl)methanol | |
| Other names Pyramin [1] | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
| ECHA InfoCard | 100.234.283 |
PubChem CID | |
| UNII | |
CompTox Dashboard (EPA) | |
| |
| |
| Properties | |
| C6H9N3O | |
| Molar mass | 139.158 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Toxopyrimidine is a vitamin B6 antagonist with potent convulsant effects. [2] [3]
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid (DNA) are nucleic acids. Along with lipids, proteins, and carbohydrates, nucleic acids constitute one of the four major macromolecules essential for all known forms of life. Like DNA, RNA is assembled as a chain of nucleotides, but unlike DNA, RNA is found in nature as a single strand folded onto itself, rather than a paired double strand. Cellular organisms use messenger RNA (mRNA) to convey genetic information that directs synthesis of specific proteins. Many viruses encode their genetic information using an RNA genome.
Ras, from "Rat sarcoma virus", is a family of related proteins that are expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells. Ras is the prototypical member of the Ras superfamily of proteins, which are all related in three-dimensional structure and regulate diverse cell behaviours.
Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to gamma-aminobutyric acid (GABA) and carbon dioxide. GAD uses pyridoxal-phosphate (PLP) as a cofactor. The reaction proceeds as follows:
The Murchison meteorite is a meteorite that fell in Australia in 1969 near Murchison, Victoria. It belongs to a group of meteorites rich in organic compounds. Due to its mass and the fact that it was an observed fall, the Murchison meteorite is one of the most studied of all meteorites.
The timeline of human evolution outlines the major events in the evolutionary lineage of the modern human species, Homo sapiens, throughout the history of life, beginning some 4 billion years ago down to recent evolution within H. sapiens during and since the Last Glacial Period.
Inositol phosphates are a group of mono- to hexaphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:
Vitamin K epoxide reductase (VKOR) is an enzyme that reduces vitamin K after it has been oxidised in the carboxylation of glutamic acid residues in blood coagulation enzymes. VKOR is a member of a large family of predicted enzymes that are present in vertebrates, Drosophila, plants, bacteria and archaea. In some plant and bacterial homologues, the VKOR domain is fused with domains of the thioredoxin family of oxidoreductases.
Wen-Hsiung Li is a Taiwanese-American scientist working in the fields of molecular evolution, population genetics, and genomics. He is currently the James Watson Professor of Ecology and Evolution at the University of Chicago and a Principal Investigator at the Institute of Information Science and Genomics Research Center, Academia Sinica, Taiwan.
The cyclol hypothesis is the now discredited first structural model of a folded, globular protein, formulated in the 1930s. It was based on the cyclol reaction of peptide bonds proposed by physicist Frederick Frank in 1936, in which two peptide groups are chemically crosslinked. These crosslinks are covalent analogs of the non-covalent hydrogen bonds between peptide groups and have been observed in rare cases, such as the ergopeptides.
Enzyme catalysis is the increase in the rate of a process by a biological molecule, an "enzyme". Most enzymes are proteins, and most such processes are chemical reactions. Within the enzyme, generally catalysis occurs at a localized site, called the active site.
David Pilbeam is the Henry Ford II Professor of the Social Sciences at Harvard University and curator of paleoanthropology at the Peabody Museum of Archaeology and Ethnology. He is a member of the National Academy of Sciences. He received his Ph.D. from Yale University.
The Pelagibacterales are an order in the Alphaproteobacteria composed of free-living marine bacteria that make up roughly one in three cells at the ocean's surface. Overall, members of the Pelagibacterales are estimated to make up between a quarter and a half of all prokaryotic cells in the ocean.
The shikimate pathway is a seven-step metabolic pathway used by bacteria, archaea, fungi, algae, some protozoans, and plants for the biosynthesis of folates and aromatic amino acids. This pathway is not found in animal cells.
Gerard Ian Evan FRS, FMedSci is a British biologist and, since May 2022, Professor of Cancer Biology at King's College London and a principal group leader in the Francis Crick Institute. Prior to this he was Sir William Dunn Professor and Head of Biochemistry at the University of Cambridge (2009-2022).
Tremorine is a drug which is used in scientific research to produce tremor in animals. This is used for the development of drugs for the treatment of Parkinson's disease, as tremor is a major symptom which is treated by anti-Parkinson's drugs. Beta blockers are also effective in counteracting the effects of tremorine.
Jared Mason Diamond is an American scientist and author best known for his popular science books The Third Chimpanzee (1991), Guns, Germs, and Steel (1997), Collapse: How Societies Choose to Fail or Succeed (2005), and The World Until Yesterday (2012). Originally trained in physiology, Diamond's work is known for drawing from a variety of fields, and he is currently Professor of Geography at the University of California, Los Angeles. The Jared Diamond bibliography includes both his scientific and popular works.
Bicyclic phosphate is a class of organophosphate compounds that are used as flame retardants, stabilizers and antioxidants. They are also used in spectroscopic studies.
Media related to Toxopyrimidine at Wikimedia Commons  | This neurotoxin article is a stub. You can help Wikipedia by expanding it. |
