![]() | |
![]() | |
Names | |
---|---|
IUPAC name 2-(Dimethylamino)ethyl N,N-dimethylphosphoramidofluoridate | |
Other names EA-5365 | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
PubChem CID | |
CompTox Dashboard (EPA) | |
| |
| |
Properties | |
C6H16FN2O2P | |
Molar mass | 198.176 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
GV (IUPAC name: 2-(Dimethylamino)ethyl N,N-dimethylphosphoramidofluoridate), also known as EA-5365 and GP (USACC cryptonym), is an organophosphate nerve agent. GV is a part of a series of nerve agents with properties similar to the "G-series" and "V-series". It is a potent acetylcholinesterase inhibitor with properties similar to other nerve agents. GV is structurally a derivative of the nerve agent tabun, being closely structurally related to fluorotabun, differing from the latter by the replacement of a proton on the alpha carbon of the alkoxide group by a dimethylamino group.
Treatment for poisoning with GV involves drugs such as atropine, benactyzine, obidoxime, and HI-6. [1] [2]
The GV agent was independently developed in the United States at the Edgewood Arsenal, under the code EA-5365, during the 1970s and in Czechoslovakia in 1983. [3] [4]
In Czechoslovakia, it was given the internal cryptonym GV. The cryptonym 'GV' also encompasses a number of similar compounds, sharing the typical structure - probably candidates for the cryptonym. [5] [6] [7] [8] In the United States, the compound is denoted by the cryptonym GP, belonging to the series of the same cryptonym. [5]
The GV compounds investigated at edgewood arsenal have a more diverse structure. [9] [10] The purpose of developing the GV agent in the United States is not known for certain, but it may be related to the development program for an binary intermediate volatility agent (IVA). [11] [12] [13] [14] Due to its tendency to polymerize and high water instability, the GV agent did not meet the requirements for an IVA agent and was replaced by a binary mixture of sarin and EA-1356. [15] [16]
As GV-2, two substances are mentioned together, EA-5615 and EA-5636, with RA probably going to deanol or deanol plus base. [14]
{{cite web}}
: CS1 maint: multiple names: authors list (link)