Schradan

Schradan

Names
Preferred IUPAC name Octamethyldiphosphoric tetraamide
Other names OMPA, Octamethyl pyrophosphoramide
Identifiers
CAS Number	152-16-9
3D model (JSmol)	Interactive image
ChEBI	CHEBI:82148
ChemSpider	8685
ECHA InfoCard	100.005.275
EC Number	205-801-0
KEGG	C19015
PubChem CID	9037
RTECS number	UX5950000
UNII	D77OYM46S1
UN number	3018
CompTox Dashboard (EPA)	DTXSID0042373
InChI InChI=1S/C8H24N4O3P2/c1-9(2)16(13,10(3)4)15-17(14,11(5)6)12(7)8/h1-8H3 Key: SZKKRCSOSQAJDE-UHFFFAOYSA-N
SMILES CN(C)P(=O)(N(C)C)OP(=O)(N(C)C)N(C)C
Properties
Chemical formula	C8H24N4O3P2
Molar mass	286.253 g·mol−1
Density	1.09
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Toxic
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300, H310, H330, H371, H373, H412
Precautionary statements	P260, P262, P264, P270, P271, P273, P280, P284, P301+P310, P302+P350, P304+P340, P309+P311, P310, P314, P320, P321, P322, P330, P361, P363, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Schradan, named after Gerhard Schrader, is an obsolete organophosphate insecticide. ^[1] Schradan itself is a weak cholinesterase inhibitor and requires metabolic activation to become active. ^[2]

See also

• Dimefox
• Mipafox

References

1. GARDINER, JE; KILBY, BA (April 1952). "Biochemistry of organic phosphorus insecticides. I. The mammalian metabolism of bis(dimethylamino) phosphonous anhydride (Schradan)". The Biochemical Journal . 51 (1): 78–85. doi:10.1042/bj0510078. PMC   1197790 . PMID   14944535.
2. DAVISON, AN (October 1955). "The conversion of schra dan (OMPA) and parathion into inhibitors of cholinesterase by mammalian liver". The Biochemical Journal . 61 (2): 203–9. doi:10.1042/bj0610203. PMC   1215773 . PMID   13260199.