Vesicle-associated membrane protein

Last updated
Synaptobrevin
Coresnarecomplex.png
Three different views of the high resolution structure of a truncated neuronal SNARE complex. Legend: synaptobrevin-2 (red), Syntaxin-1 (pink), SNAP-25 (purple).
Identifiers
SymbolSynaptobrevin
Pfam PF00957
InterPro IPR016444
PROSITE PDOC00368
SCOP2 1sfc / SCOPe / SUPFAM
OPM superfamily 197
OPM protein 4wy4
Membranome 198
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary
Hypothetic models of VAMP2 conformations and engagement in SNARE complex assembly for neurotransmitter release Hypothetic models of VAMP2 conformations and engagement in SNARE complex assembly for neurotransmitter release.pdf
Hypothetic models of VAMP2 conformations and engagement in SNARE complex assembly for neurotransmitter release

Vesicle associated membrane proteins (VAMPs) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion.

References

  1. Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH (1999). "Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking". Mol. Biol. Cell. 10 (6): 1957–72. doi:10.1091/mbc.10.6.1957. PMC   25394 . PMID   10359608.