SYT7

Last updated
SYT7
Protein SYT7 PDB 2d8k.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SYT7 , IPCA-7, IPCA7, PCANAP7, SYT-VII, SYTVII, synaptotagmin 7
External IDs OMIM: 604146; MGI: 1859545; HomoloGene: 20889; GeneCards: SYT7; OMA:SYT7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018801
NM_173067
NM_173068
NM_001373944

RefSeq (protein)

NP_061271
NP_775090
NP_775091

Location (UCSC) Chr 11: 61.51 – 61.58 Mb Chr 19: 10.37 – 10.43 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Synaptotagmin-7 is a protein that in humans is encoded by the SYT7 gene. [5] [6]

Contents

Function

Synaptotagmins, such as SYT7, are calcium-dependent phospholipid-binding proteins known for their role in synaptic exocytosis and neurotransmitter release. Significant expression has also been observed in the prostate and other tissues. See MIM 600782 [supplied by OMIM] [6]

Interactions

SYT7 has been shown to interact with SYNCRIP. [7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000011347 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024743 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Cooper PR, Nowak NJ, Higgins MJ, Church DM, Shows TB (May 1998). "Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes". Genomics. 49 (3): 419–29. doi:10.1006/geno.1998.5291. PMID   9615227.
  6. 1 2 "Entrez Gene: SYT7 synaptotagmin VII".
  7. Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". The Journal of Biological Chemistry. 275 (13): 9823–31. doi: 10.1074/jbc.275.13.9823 . PMID   10734137.

Further reading