3152 CT

Last updated
3152 CT
3152 CT.png
Names
Preferred IUPAC name
3-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethyl-5-{{#parsoidfragment:0}}{3-[3-(trimethylazaniumyl)phenoxy]propoxy}anilinium diiodide
Identifiers
3D model (JSmol)
  • InChI=1S/C18H23N3O4.2HI/c1-21(2)18(22)25-17-11-14(20)10-16(12-17)24-8-4-7-23-15-6-3-5-13(19)9-15;;/h3,5-6,9-12H,4,7-8,19-20H2,1-2H3;2*1H
    Key: KDBKYZAHSYSXLC-UHFFFAOYSA-N
  • [NH3+]c(c1)cccc1OCCCOc(cc([NH3+])c2)cc2OC(=O)N(C)C.[I-].[I-]
Properties
C24H37I2N3O4
Molar mass 685.386 g·mol−1
AppearanceSolid [1]
Melting point 182–184 [1]  °C (360–363 °F; 455–457 K)
Hazards
Lethal dose or concentration (LD, LC):
16 μg/kg (intravenous, mice) [1]
8 μg/kg (intravenous, rabbits) [1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

3152 CT is an extremely toxic bisquaternary carbamate with powerful anticholinesterase action. [2] It has an LD50 in rats and rabbits 10 times lower than that of the GB agent and, on a molar basis, is 30 times more toxic than the latter. [3]

See also

References

  1. 1 2 3 4 "Method for methylating and quaternizing".
  2. ↑ LEVIN, AP; JANDORF, BJ (February 1955). "Inactivation of cholinesterase by compounds related to neostigmine". The Journal of Pharmacology and Experimental Therapeutics. 113 (2): 206–11. doi:10.1016/S0022-3565(25)11504-8. PMID   13234044.
  3. ↑ WILLIAM H. SUMMERSON - Deputy Commander for Scientific Activities, USA CmIC Research and Development Command, Washington, D. C.. The Chemical Warfare Threat. NONMILITARY DEFENSE - Chemical and Biological Defenses in Perspective. ACS, 1960.


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