TL-301

Last updated
TL-301
TL-301.svg
Names
IUPAC name
N,N-bis(2-chloroethyl)propan-2-amine
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
  • InChI=1S/C7H15Cl2N/c1-7(2)10(5-3-8)6-4-9/h7H,3-6H2,1-2H3
    Key: WAEDMQMDOHQPFL-UHFFFAOYSA-N
  • CC(C)N(CCCl)CCCl
Properties
Melting point 13.7 [1]  °C (56.7 °F; 286.8 K)
Boiling point 67–68 [1]  °C (153–154 °F; 340–341 K)
Hazards
Lethal dose or concentration (LD, LC):
1.1 mg/kg (subcutaneous, mice)(hydrochloride salt) [2]
1 mg/kg (subcutaneous, rats)(hydrochloride salt) [2]
0.5 mg/kg (intravenous, rat)(hydrochloride salt) [2]
22 mg/kg (oral, mice)(hydrochloride salt) [2]
0.5 mg/kg (subcutaneous, mice)(hydrochloride salt) [3]
2 mg/kg (subcutaneous, rats)(hydrochloride salt) [3]
25 mg/kg (oral, rats)(hydrochloride salt) [4]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

TL-301 is a type of nitrogen mustard. [1] [2] [3]

See also

References

  1. 1 2 3 "Chemical Warfare Agents, and Related Chemical Problems. Parts I-II". 1958.
  2. 1 2 3 4 5 "Chemical Warfare Agents, and Related Chemical Problems, Parts III-VI-Summary Technical Report".
  3. 1 2 3 Boyland, E (December 1946). "The toxicity of alkyl-bis(beta-chloroethyl)amines and of the products of their reaction with water". British Journal of Pharmacology and Chemotherapy. 1 (4): 247–54. doi:10.1111/j.1476-5381.1946.tb00044.x. PMC   1509752 . PMID   19108094.
  4. ↑ Witt, James B. De (1953). Relationship Between Chemical Structure and Toxic Action on Rats. Chemical-Biological Coordination Center, National Research Council.
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