KB-16

KB-16
Names
	Preferred IUPAC name Methyl (2-chloroethyl)nitrosocarbamate
	Other names TL-186
Identifiers
CAS Number	13589-15-6 ;
3D model (JSmol)	Interactive image ;
ChemSpider	24333 ;
PubChem CID	26121 ;
CompTox Dashboard (EPA)	DTXSID60159588 ;
	InChI InChI=1S/C4H7ClN2O3/c1-10-4(8)7(6-9)3-2-5/h2-3H2,1H3 Key: ZIVWROYTZSSKDC-UHFFFAOYSA-N;
	SMILES COC(=O)N(CCCl)N=O;
Properties
Chemical formula	C4H7ClN2O3
Molar mass	166.56 g·mol−1
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	1.1 mg/kg (intravenous, rats); 20 mg/kg (oral, rats); 8 mg/kg (subcutaneous, rats)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated August 18, 2025

KB-16 is a nitrosocarbamate vesicant.^[1]^[2] KB-16 is part of the corneal clouding chemical warfare agents. KB-16 clouds the cornea for a long time.^[3]

References

1 2 3 4 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
↑ Thompson, RH (15 January 1947). "The action of chemical vesicants on cholinesterase". The Journal of Physiology. 105 (4): 370–81. doi:10.1113/jphysiol.1947.sp004177. PMC 1393670 . PMID 16991733.
↑ "INCAPACITATING CHEMICAL AGENTS": LAW ENFORCEMENT, HUMAN RIGHTS LAW AND POLICY PERSPECTIVES. p-89.

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[PB158508-1] 1 2 3 4 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.

[2] Thompson, RH (15 January 1947). "The action of chemical vesicants on cholinesterase". The Journal of Physiology. 105 (4): 370–81. doi:10.1113/jphysiol.1947.sp004177. PMC 1393670 . PMID 16991733.

[3] "INCAPACITATING CHEMICAL AGENTS": LAW ENFORCEMENT, HUMAN RIGHTS LAW AND POLICY PERSPECTIVES. p-89.

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[2]

[3]

Names

Preferred IUPAC name Methyl (2-chloroethyl)nitrosocarbamate
Other names TL-186
Identifiers
CAS Number	13589-15-6
3D model (JSmol)	Interactive image
ChemSpider	24333
PubChem CID	26121
CompTox Dashboard (EPA)	DTXSID60159588
InChI InChI=1S/C4H7ClN2O3/c1-10-4(8)7(6-9)3-2-5/h2-3H2,1H3 Key: ZIVWROYTZSSKDC-UHFFFAOYSA-N
SMILES COC(=O)N(CCCl)N=O
Properties
Chemical formula	C₄H₇ClN₂O₃
Molar mass	166.56 g·mol⁻¹
Hazards
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	1.1 mg/kg (intravenous, rats)^[1] 20 mg/kg (oral, rats)^[1] 8 mg/kg (subcutaneous, rats)^[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

KB-16

See also

References