Names | |
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Preferred IUPAC name Dibenzo[b,f][1,4]oxazepine | |
Identifiers | |
3D model (JSmol) | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.114.990 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C13H9NO | |
Molar mass | 195.221 g·mol−1 |
Density | 1.160±0.10 g/cm3 |
Melting point | 73 °C (163 °F; 346 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
CR gas or dibenzoxazepine (chemical name dibenz[b,f][1,4]oxazepine, is an incapacitating agent and a lachrymatory agent. CR was developed by the British Ministry of Defence as a riot control agent in the late 1950s and early 1960s. A report from the Porton Down laboratories described exposure as "like being thrown blindfolded into a bed of stinging nettles", and it earned the nickname "firegas". [1] [2]
In its effects, CR gas is very similar to CS gas (o-chlorobenzylidene malononitrile), but twice as potent, even though there is little structural resemblance between the two. For example, 2 mg of dry CR causes skin redness in 10 min, 5 mg causes burning and erythremia, and 20 mgstrong pain. Water usually amplifies the pain effect of CR on skin. CR aerosols cause irritation at concentrations of 0.2 — mcg/L, becoming intolerable at 3 mcg/L. The LD50 of CR through air inhalation 350 mg·min/L. [3]
CR is a pale yellow crystalline solid with a spicy odor. It is slightly soluble in water and does not degrade in it. CR is usually presented as a microparticulate solid, in the form of suspension in a propylene glycol-based liquid. Contrary to its common name, it is not a gas but a solid at room temperature.
The dibenz[b,f][1,4]oxazepine moiety is present in the typical antipsychotic drug loxapine, but, unlike CR, loxapine is not reactive and is not an irritant. CR was first synthesised in 1962. [4]
CR can be delivered either as an aerosol or a solution in water, making it able to be used in water cannons, smoke grenades, or handheld spray cans. For smoke it is usually fired in canisters (LACR) that heat up, producing an aerosol cloud at a steady rate.
CR gas is a lachrymatory agent (LA), exerting its effects through activation of the TRPA1 channel. [5] [6] [7] Its effects are approximately 6 to 10 times more powerful than those of CS gas. CR causes intense skin irritation, in particular around moist areas; blepharospasm, causing temporary blindness; and coughing, gasping for breath, and panic. It is capable of causing immediate incapacitation. It is a suspected carcinogen. It is toxic, but less so than CS gas, by ingestion and exposure. However, it can be lethal in large quantities. In a poorly ventilated space, an individual may inhale a lethal dose within minutes. Death is caused by asphyxiation and pulmonary edema.
The effect of CR is long-term and persistent. CR can persist on surfaces, especially porous ones, for up to 60 days.
While CS can be decontaminated with a large amount of water, use of water may exacerbate the effects of CR. Skin contaminated with CR gas may become extremely painful in contact with water for up to 48 hours after contamination. [4]
Medical treatment is mostly palliative. The contaminated clothing has to be removed. The eyes and skin can be washed, the eye pain can be alleviated with medications. [8]
During the 2011 protests against the military government in Egypt, Egyptian security forces allegedly used CR gas in addition to the more commonly used, less debilitating CS gas. One protester described the gas as making him feel "as if your eyes are about to fall out; then you have trouble breathing, and you lose your sight". Egyptians used yeast as a treatment for CR side effects on skin. Mohammed ElBaradei also confirmed via Twitter that "tear gas with [a] nerve agent" is being used in Tahrir Square. [9]
The only gas that has been identified by human rights organizations in protests "is CS tear gas, typically used by police forces to disperse crowds," stated Egyptian journalist Farida Helmy. [10] Egyptian use of CR gas has not been corroborated according to Human Rights Watch.
People occupying an area in Notre-Dame-des-Landes against an airport project suspect the use of CR gas by French Police and Army in April 2018. [11]
It started being available in police and army supplies, as a water cannon additive and as spray cans, in 1973 and was at least still so in 1981. [1] [2]
Republican groups in Northern Ireland have alleged that British Army and Royal Ulster Constabulary units used CR gas against Republican prisoners in the 1970s. [12] Additionally, there are British military documents now declassified and in the public domain held in the records of the UK Ministry of Defence at the National Archives, London, that suggest that the British Army did deploy and use CR gas in Northern Ireland. [13] [14] [15] [16] [17]
CR tear gas was used in suppression of the mutiny in Makati that was led by Sen. Antonio Trillanes. The tear gas was fired in the building and all the people in the building including reporters were affected.[ citation needed ]
In the late 1980s, CR was used in the townships in South Africa. It caused some fatalities, in particular among children. [18] [19]
The Tamil Tigers of Sri Lanka, an insurgent group in Sri Lanka used CR gas against government forces that were on an offensive to flush and defeat these insurgents during September 2008. Its use hindered the army's progress but ultimately proved ineffective in preventing the army from overrunning their positions. This is one of the first few cases of insurgents using CR gas as an insurgent weapon.[ citation needed ]
In the June 2013 protest against the Turkish government, Turkish police allegedly used CR gas on protesters in Istanbul. Doctors in a makeshift first aid post in a Mosque judged it as such. [20] [21]
In Ukraine, CR gas is commonly used by special forces against demonstrators. Gas is packed in a form of spray cans "Cobra 1". For example, gas has been used on demonstration dedicated to Ukraine Independence Day (Aug 24 2011). [22] Also massive gas usage has been documented during demonstrations against Language Law Draft at Kiev on Jul 3-4 2012. [23]
Non-lethal weapons, also called nonlethal weapons, less-lethal weapons, less-than-lethal weapons, non-deadly weapons, compliance weapons, or pain-inducing weapons are weapons intended to be less likely to kill a living target than conventional weapons such as knives and firearms with live ammunition. It is often understood that unintended or incidental casualties are risked wherever force is applied, however non-lethal weapons minimise the risk of casualties as much as possible. Non-lethal weapons are used in policing and combat situations to limit the escalation of conflict where employment of lethal force is prohibited or undesirable, where rules of engagement require minimum casualties, or where policy restricts the use of conventional force. However, these weapons occasionally cause serious injuries or death due to allergic reactions, improper use and/or other factors; for this reason the term "less-lethal" has been preferred by some organizations as it describes the risks of death more accurately than the term "non-lethal", which some have argued is a misnomer.
Pepper spray, oleoresin capsicum spray, OC spray, capsaicin spray, or capsicum spray is a lachrymator product containing the compound capsaicin as the active ingredient that irritates the eyes to cause burning and pain sensations, as well as temporary blindness. Its inflammatory effects cause the eyes to close, temporarily taking away vision. This temporary blindness allows officers to more easily restrain subjects and permits people in danger to use pepper spray in self-defense for an opportunity to escape. It also causes temporary discomfort and burning of the lungs which causes shortness of breath. Pepper spray is used as a less lethal weapon in policing, riot control, crowd control, and self-defense, including defense against dogs and bears.
The compound 2-chlorobenzalmalononitrile (also called o-chlorobenzylidene malononitrile; chemical formula: C10H5ClN2), a cyanocarbon, is the defining component of the lachrymatory agent commonly referred to as CS gas, a tear gas which is used as a riot control agent.
Phenacyl chloride, also commonly known as chloroacetophenone, is a substituted acetophenone. It is a useful building block in organic chemistry. Apart from that, it has been historically used as a riot control agent, where it is designated CN. It should not be confused with cyanide, another agent used in chemical warfare, which has the chemical structure CN−. Chloroacetophenone is thermally stable, and is the only tear agent that is distillable at ambient conditions.
A water cannon is a device that shoots a high-velocity stream of water. Typically, a water cannon can deliver a large volume of water, often over dozens of meters. They are used in firefighting, large vehicle washing, riot control, and mining. Most water cannons fall under the category of a fire monitor.
Riot control measures are used by law enforcement, military, paramilitary or security forces to control, disperse, and arrest people who are involved in a riot, unlawful demonstration or unlawful protest.
Tear gas, also known as a lachrymatory agent or lachrymator, sometimes colloquially known as "mace" after the early commercial self-defense spray, is a chemical weapon that stimulates the nerves of the lacrimal gland in the eye to produce tears. In addition, it can cause severe eye and respiratory pain, skin irritation, bleeding, and blindness. Common lachrymators both currently and formerly used as tear gas include pepper spray, PAVA spray (nonivamide), CS gas, CR gas, CN gas, bromoacetone, xylyl bromide and Mace.
Triamcinolone is a glucocorticoid used to treat certain skin diseases, allergies, and rheumatic disorders among others. It is also used to prevent worsening of asthma and COPD. It can be taken in various ways including by mouth, injection into a muscle, and inhalation.
A gas duster, also known as tinned wind or compressed air, is a product used for cleaning or dusting electronic equipment and other sensitive devices that cannot be cleaned using water.
4-Nonanoylmorpholine [pelargonic acid morpholide, N-nonanoylmorpholine, MPK or МПК, or MPA] is an amide of pelargonic acid and morpholine.
PAVA spray is an incapacitant spray similar to pepper spray. It is dispensed from a handheld canister, in a liquid stream. It contains a 0.3% solution of pelargonic acid vanillylamide (PAVA), also called nonivamide, a synthetic capsaicinoid, in a solvent of aqueous ethanol. The propellant is nitrogen. This solution has been selected because this is the minimum concentration which will fulfill the purpose of the equipment; namely to minimise a person's capacity for resistance, without unnecessarily prolonging their discomfort.
A smoke composition is a pyrotechnic composition designed primarily to generate smoke. Smoke compositions are used as obscurants or for generation of signaling smokes. Some are used as a payload of smoke bombs and smoke grenades.
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Wasabi Receptor, is a protein that in humans is encoded by the TRPA1 gene.
Skunk is a malodorant, non-lethal weapon used for crowd control by the Israel Defense Forces (IDF) and marketed to militaries and law enforcement around the world. It was developed and is manufactured by Odortec, with two supporting companies, Man and Beit-Alfa Technologies. The liquid's strong odor is marketed as an improvement over other crowd control weapons (CCWs) such as rubber bullets and tear gas used by the IDF against Palestinian protestors. The IDF has been criticized for its tactics during deployment, including common use against people, businesses, and neighborhoods not involved in protests as a form of collective punishment.
An aerosol frostbite of the skin is an injury to the body caused by the pressurized gas within an aerosol spray cooling quickly, with the sudden drop in temperature sufficient to cause frostbite to the applied area. Medical studies have noted an increase of this practice, known as "frosting", in pediatric and teenage patients.
Chemical weapons were reported to have been used by the Sri Lankan military and the rebel Liberation Tigers of Tamil Eelam (LTTE) during the Sri Lankan Civil War.
A blast ball, also known as a tear gas ball, rubber ball grenade, sting ball grenade, or stinger grenade, is a ball-shaped, rubber coated, less-lethal grenade designed for law enforcement and riot control applications. A blast ball is similar to a stun grenade in that, when detonated, it generates a loud noise and bright light; however, it also releases a chemical irritant and occasionally also rubber pellets or fragments.
Edson Da Costa was a 25-year-old Black Portuguese man who died on 21 June 2017 after being stopped by police on 15 June in Beckton, London. The unclear circumstances of his death led to protests. In June 2019, an inquest jury found that Da Costa died by misadventure from the consequences of a cardiorespiratory arrest after he placed in his mouth a plastic bag containing 88 wraps of class A drugs. The coroner ruled that there was no "legal or factual basis" for a conclusion that could be critical of the police. An investigation by the Independent Office for Police Conduct concluded that the restraint by officers was necessary and proportionate.