Euphorbia is a very large and diverse genus of flowering plants, commonly called spurge, in the family Euphorbiaceae.
Irritation, in biology and physiology, is a state of inflammation or painful reaction to allergy or cell-lining damage. A stimulus or agent which induces the state of irritation is an irritant. Irritants are typically thought of as chemical agents but mechanical, thermal (heat), and radiative stimuli can also be irritants. Irritation also has non-clinical usages referring to bothersome physical or psychological pain or discomfort.
Balsam is the resinous exudate which forms on certain kinds of trees and shrubs. Balsam owes its name to the biblical Balm of Gilead.
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes are not contagious or life-threatening, but can be very uncomfortable.
Euphorbia cyparissias, the cypress spurge, is a species of plant in the genus Euphorbia. It is native to Europe and was introduced to North America in the 1860s as an ornamental plant.
Euphorbium, an acrid dull-yellow or brown resin, consisting of the concreted milky juice of several species of Euphorbia, cactus-like perennial plants indigenous to Morocco. It dissolves in alcohol, ether and turpentine; in water it is only slightly soluble. It consists of two or more resins and a substance euphorbone, C20H36O or C15H24O. Pliny the Elder states that the name of the drug was given to it in honor of Euphorbus, the physician of Juba II, king of Mauretania. In former times euphorbium was valued in medicine for its drastic, purgative and emetic properties.
Euphorbia tithymaloides is a perennial succulent spurge. An erect shrub, the plant is also known by the scientific name Pedilanthus tithymaloides. However, the genus Pedilanthus has been subsumed into the genus Euphorbia, and is more correctly known by its new name.
Euphorbia milii, the crown of thorns, Christ plant, or Christ's thorn, is a species of flowering plant in the spurge family Euphorbiaceae, native to Madagascar. The species name commemorates Baron Milius, once Governor of Réunion, who introduced the species to France in 1821.
Resiniferatoxin (RTX) is a naturally occurring chemical found in resin spurge, a cactus-like plant commonly found in Morocco, and in Euphorbia poissonii found in northern Nigeria. It is a potent functional analog of capsaicin, the active ingredient in chili peppers.
Euphorbia resinifera, the resin spurge, is a species of spurge native to Morocco, where it occurs on the slopes of the Atlas Mountains. The dried latex of the plant was used in ancient medicine. It contains resiniferatoxin, an extremely potent capsaicin analog tested as an analgesic since 1997.
Phorbol is a natural, plant-derived organic compound. It is a member of the tigliane family of diterpenes. Phorbol was first isolated in 1934 as the hydrolysis product of croton oil, which is derived from the seeds of the purging croton, Croton tiglium. The structure of phorbol was determined in 1967. Various esters of phorbol have important biological properties, the most notable of which is the capacity to act as tumor promoters through activation of protein kinase C. They mimic diacylglycerols, glycerol derivatives in which two hydroxyl groups have reacted with fatty acids to form esters. The most common and potent phorbol ester is 12-O-tetradecanoylphorbol-13-acetate (TPA), also called phorbol-12-myristate-13-acetate (PMA), which is used as a biomedical research tool in contexts such as models of carcinogenesis.
A laticifer is a type of elongated secretory cell found in the leaves and/or stems of plants that produce latex and rubber as secondary metabolites. Laticifers may be divided into:
Tinyatoxin is an analog of the neurotoxin resiniferatoxin. It occurs naturally in Euphorbia poissonii.
Transient receptor potential cation channel subfamily M (melastatin) member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein that in humans is encoded by the TRPM8 gene. The TRPM8 channel is the primary molecular transducer of cold somatosensation in humans. In addition, mints can desensitize a region through the activation of TRPM8 receptors.
Euphorbia candelabrum is a succulent species of plant in the family Euphorbiaceae, one of several plants commonly known as candelabra tree. It is endemic to the Horn of Africa and eastern Africa along the East African Rift system. It is known in Ethiopia by its Amharic name, qwolqwal, or its Oromo name, adaamii. It is closely related to three other species of Euphorbia: Euphorbia ingens in the dry regions of southern Africa, Euphorbia conspicua from western Angola, and Euphorbia abyssinica, which is native to countries including Sudan, Eritrea, Djibouti, Ethiopia and Somalia.
Euphorbiaceae, the spurge family, is a large family of flowering plants. In English, they are also commonly called euphorbias, which is also the name of the type genus of the family. Most spurges, such as Euphorbia paralias, are herbs, but some, especially in the tropics, are shrubs or trees, such as Hevea brasiliensis. Some, such as Euphorbia canariensis, are succulent and resemble cacti because of convergent evolution. This family has a cosmopolitan global distribution. The greatest diversity of species is in the tropics; however, the Euphorbiaceae also have many species in nontropical areas of all continents except Antarctica.
Euphorbia ingens is a species of flowering plant in the family Euphorbiaceae. It is native to dry areas of southern Africa. It is popularly known as the candelabra tree or naboom. Its milky latex can be extremely poisonous and is a dangerous irritant.
Iodoresiniferatoxin (I-RTX) is a strong competitive antagonist of the Transient Receptor Potential Vanilloid 1 (TRPV1) receptor. I-RTX is derived from resiniferatoxin (RTX).
Euphorbia miliivar.splendens is a variety of the species Euphorbia milii. Like the other varieties of E. miliiE. m. var. splendens produces a milky latex that is an irritant poison. Under the name sijou the plant, known formerly as Euphorbia splendens, is considered to be sacred in the Bathouist religion of the Bodo people of Assam, West Bengal, Nagaland and Nepal, in which it symbolizes the supreme deity, Bathoubwrai. This cultivation of the sijou tree for ritual purposes was particularly strong among the Bodo people of the Goalpara region. The plant does not often set seed, but is easy to propagate vegetatively; branches broken from an established plant root readily as cuttings. Families that follow Bathouism plant a sijou shrub at the northeast corner of their courtyard in an altar referred to as the sijousali. Bodo communities that follow Bathouism generally plant a sijou shrub or small tree in a piece of communally-owned land, which they fence with eighteen pairs of bamboo strips with five fastenings. Each pair symbolizes a divine couple consisting of a minor God and Goddess. From bottom to top, the five fastenings signify birth, pain, death, marriage and peace/pleasure. The milestones on the path of life represented by the bottom three fastenings are those that one cannot escape; whereas those symbolized by the top two are not necessarily attained by all.
Excoecaria agallocha, a mangrove species, belongs to the genus Excoecaria of the family Euphorbiaceae. The species has many common names, including blind-your-eye mangrove, blinding tree, buta buta tree, milky mangrove, poisonfish tree, and river poison tree. Most of the names refer to its toxic properties or its propensity to cause blindness when its latex comes into contact with the eyes.
