Dihydropicrotoxinin

Dihydropicrotoxinin
Identifiers
CAS Number	17617-46-8 ;
3D model (JSmol)	Interactive image ;
ChemSpider	108864 ;
PubChem CID	122052 ;
	InChI InChI=1S/C15H18O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h5-10,18H,4H2,1-3H3/t6?,7?,8-,9?,10-,13-,14-,15?/m1/s1 Key: SJSFJVFGSPJGET-KJINDDCRSA-N;
	SMILES CC(C)C1[C@@H]2C(=O)OC1[C@@H]3[C@@]4([C@]2(CC5C4(O5)C(=O)O3)O)C;
Properties
Chemical formula	C15H18O6
Molar mass	294.303 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated June 01, 2025

Dihydropicrotoxinin is the saturated derivative of picrotoxinin. Its radiolabeled derivative, [³H]dihydropicrotoxinin, is used in scientific research to study the GABA receptors.^[1]

References

↑ Olsen, R. W (2006). "Picrotoxin-like channel blockers of GABAA receptors". Proceedings of the National Academy of Sciences of the United States of America. 103 (16): 6081–2. Bibcode:2006PNAS..103.6081O. doi: 10.1073/pnas.0601121103 . PMC 1458832 . PMID 16606858.

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[1] Olsen, R. W (2006). "Picrotoxin-like channel blockers of GABAA receptors". Proceedings of the National Academy of Sciences of the United States of America. 103 (16): 6081–2. Bibcode:2006PNAS..103.6081O. doi: 10.1073/pnas.0601121103 . PMC 1458832 . PMID 16606858.

[1]

v t e Convulsants
GABA receptor antagonists	Bicuculline Bicyclic phosphates (TBPS, TBPO, IPTBO) BIDN Chlorophenylsilatrane Cicutoxin Cloflubicyne Coriamyrtin Dihydropicrotoxinin DMCM EBOB Endosulfan FG-7142 Fipronil Flurothyl Gabazine Oenanthotoxin Pentylenetetrazol Phenylsilatrane Picrotoxin p-CN-TBOB p-NCS-TBOB RDX TBOB Tetramethylenedisulfotetramine Thujone Trimethylolpropane phosphite Tutin
GABA synthesis inhibitors	3-Mercaptopropionic acid 4-Deoxypyridoxine Allylglycine Crimidine Decaborane Ginkgotoxin Isoniazid Pentaborane Thiocarbohydrazide Toxopyrimidine
Glycine receptor antagonists	Coriamyrtin Dendrobine Picrotoxin Strychnine Tutin
Glutamate receptor agonists	AMPA Domoic acid Kainic acid NMDA Quisqualic acid Tetrazolylglycine
Convulsant barbiturates	CHEB Diberal (DMBB) McN-481
Other	2,2,3,3-Tetrafluoropropyl trifluoromethyl ether Bromocamphor Camphor FAZ-4 Fluoroethyl fluoroacetate MC-2973 Methionine sulfoximine Methyl fluoroacetate Nitrocyclohexane Thebaine

Identifiers

CAS Number	17617-46-8
3D model (JSmol)	Interactive image
ChemSpider	108864
PubChem CID	122052
InChI InChI=1S/C15H18O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h5-10,18H,4H2,1-3H3/t6?,7?,8-,9?,10-,13-,14-,15?/m1/s1 Key: SJSFJVFGSPJGET-KJINDDCRSA-N
SMILES CC(C)C1[C@@H]2C(=O)OC1[C@@H]3[C@@]4([C@]2(CC5C4(O5)C(=O)O3)O)C
Properties
Chemical formula	C₁₅H₁₈O₆
Molar mass	294.303 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Dihydropicrotoxinin

See also

References