Englitazone

Englitazone
Clinical data
ATC code	none;
Identifiers
	IUPAC name 5-[(2-Benzyl-3,4-dihydro-2H-chromen-6-yl)methyl]-1,3-thiazolidine-2,4-dione;
CAS Number	109229-58-5 ;
PubChem CID	60303 ;
ChemSpider	54375 ;
UNII	ZQW5577C3O ;
ChEMBL	ChEMBL17669 ;
CompTox Dashboard (EPA)	DTXSID80883191 ;
Chemical and physical data
Formula	C20H19NO3S
Molar mass	353.44 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES O=C1NC(=O)SC1Cc4ccc3OC(Cc2ccccc2)CCc3c4;

Last updated November 29, 2025

Englitazone is a hypoglycemic agent of thiazolidinedione (glitazone) class.^[1]

References

↑ Kumar H, Aggarwal N, Marwaha MG, Deep A, Chopra H, Matin MM, et al. (October 2022). "Thiazolidin-2,4-Dione Scaffold: An Insight into Recent Advances as Antimicrobial, Antioxidant, and Hypoglycemic Agents". Molecules. 27 (19): 6763. doi: 10.3390/molecules27196763 . PMC 9572748 . PMID 36235304.

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[Kumar_2022-1] Kumar H, Aggarwal N, Marwaha MG, Deep A, Chopra H, Matin MM, et al. (October 2022). "Thiazolidin-2,4-Dione Scaffold: An Insight into Recent Advances as Antimicrobial, Antioxidant, and Hypoglycemic Agents". Molecules. 27 (19): 6763. doi: 10.3390/molecules27196763 . PMC 9572748 . PMID 36235304.

[1]

v t e PPAR Tooltip Peroxisome proliferator-activated receptor modulators
PPARα Tooltip Peroxisome proliferator-activated receptor alpha	Agonists: 15-HETE 15-HpETE Aleglitazar Aluminium clofibrate Arachidonic acid Bezafibrate Chiglitazar Clofibrate CP-775146 Daidzein DHEA (prasterone) (in rodents) Elafibranor Etomoxir Fenofibrate Genistein Gemfibrozil GW-7647 Lanifibranor Leukotriene B₄ LG-101506 LG-100754 Lobeglitazone Muraglitazar Oleylethanolamide Palmitoylethanolamide Pemafibrate Perfluorononanoic acid Perfluorooctanoic acid Pioglitazone Saroglitazar Sodelglitazar Tesaglitazar Tetradecylthioacetic acid Troglitazone WY-14643 Antagonists: GW-6471 MK-886
PPARδ Tooltip Peroxisome proliferator-activated receptor delta	Agonists: 15-HETE 15-HpETE Arachidonic acid Bezafibrate Daidzein Elafibranor Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Antagonists: FH-535 GSK-0660 GSK-3787
PPARγ Tooltip Peroxisome proliferator-activated receptor gamma	Agonists: 5-Oxo-ETE 5-Oxo-15-hydroxy-ETE 15-Deoxy-Δ^12,14-prostaglandin J₂ 15-HETE 15-HpETE Aleglitazar Arachidonic acid Balaglitazone Berberine Bezafibrate Cannabidiol Cevoglitazar Chiglitazar Ciglitazone Daidzein Darglitazone Edaglitazone Efatutazone Englitazone Etalocib Farglitazar Genistein GW-1929 Ibuprofen Imiglitazar Indeglitazar Lanifibranor LG-100268 LG-100754 LG-101506 Lobeglitazone Muraglitazar (muroglitazar) nTZDpa Naveglitazar Netoglitazone Oxeglitazar Peliglitazar Pemaglitazar Perfluorononanoic acid Pioglitazone Prostaglandin J₂ Ragaglitazar Reglitazar Rivoglitazone Rosiglitazone RS5444 Saroglitazar Sipoglitazar Sodelglitazar Telmisartan Tesaglitazar Troglitazone SPPARMs Tooltip Selective PPARγ modulator: BADGE EPI-001 INT-131 MK-0533 S26948 Antagonists: FH-535 GW-9662 SR-202 T-0070907 Unknown: SR-1664
Non-selective	Agonists: Ciprofibrate Clinofibrate Clofibride Englitazone Etofibrate Farglitazar Netoglitazone Ronifibrate Rivoglitazone Simfibrate
See also Receptor/signaling modulators

Clinical data

ATC code	none
Identifiers
IUPAC name 5-[(2-Benzyl-3,4-dihydro-2H-chromen-6-yl)methyl]-1,3-thiazolidine-2,4-dione
CAS Number	109229-58-5
PubChem CID	60303
ChemSpider	54375
UNII	ZQW5577C3O
ChEMBL	ChEMBL17669
CompTox Dashboard (EPA)	DTXSID80883191
Chemical and physical data
Formula	C₂₀H₁₉NO₃S
Molar mass	353.44 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C1NC(=O)SC1Cc4ccc3OC(Cc2ccccc2)CCc3c4

Englitazone

See also

References