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| ECHA InfoCard | 100.233.314 |
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| Formula | C21H16FNO3S |
| Molar mass | 381.42 g·mol−1 |
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Netoglitazone (also called MCC-555) is a hypoglycemic agent belonging to the thiazolidinedione group. [1]
A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility. Bones come in a variety of shapes and sizes and have complex internal and external structures. They are lightweight yet strong and hard and serve multiple functions.
The foot is an anatomical structure found in many vertebrates. It is the terminal portion of a limb which bears weight and allows locomotion. In many animals with feet, the foot is a separate organ at the terminal part of the leg made up of one or more segments or bones, generally including claws or nails.
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to bone fragility, and consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. After the broken bone heals, the person may have chronic pain and a decreased ability to carry out normal activities.
A skeleton is the structural frame that supports the body of an animal. There are several types of skeletons, including the exoskeleton, which is the stable outer shell of an organism, the endoskeleton, which forms the support structure inside the body, and the hydroskeleton, a flexible internal skeleton supported by fluid pressure. Vertebrates are animals with a vertebral column, and their skeletons are typically composed of bone and cartilage. Invertebrates are animals that lack a vertebral column. The skeletons of invertebrates vary, including hard exoskeleton shells, plated endoskeletons, or spicules. Cartilage is a rigid connective tissue that is found in the skeletal systems of vertebrates and invertebrates.
Saint Nicholas of Myra, also known as Nicholas of Bari, was an early Christian bishop of Greek descent from the maritime city of Myra in Asia Minor during the time of the Roman Empire. Because of the many miracles attributed to his intercession, he is also known as Nicholas the Wonderworker. Saint Nicholas is the patron saint of sailors, merchants, archers, repentant thieves, children, brewers, pawnbrokers, unmarried people, and students in various cities and countries around Europe. His reputation evolved among the pious, as was common for early Christian saints, and his legendary habit of secret gift-giving gave rise to the traditional model of Santa Claus through Sinterklaas.
The human skeleton is the internal framework of the human body. It is composed of around 270 bones at birth – this total decreases to around 206 bones by adulthood after some bones get fused together. The bone mass in the skeleton makes up about 14% of the total body weight and reaches maximum density around age 21. The human skeleton can be divided into the axial skeleton and the appendicular skeleton. The axial skeleton is formed by the vertebral column, the rib cage, the skull and other associated bones. The appendicular skeleton, which is attached to the axial skeleton, is formed by the shoulder girdle, the pelvic girdle and the bones of the upper and lower limbs.
The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, these two parts are the neurocranium and the viscerocranium that includes the mandible as its largest bone. The skull forms the anterior-most portion of the skeleton and is a product of cephalisation—housing the brain, and several sensory structures such as the eyes, ears, nose, and mouth. In humans these sensory structures are part of the facial skeleton.
Skull and Bones, also known as The Order, Order 322 or The Brotherhood of Death, is an undergraduate senior secret student society at Yale University in New Haven, Connecticut. The oldest senior class society at the university, Skull and Bones has become a cultural institution known for its powerful alumni and various conspiracy theories. It is one of the "Big Three" societies at Yale, the other two being Scroll and Key and Wolf's Head.
The clavicle, or collarbone, is a slender, S-shaped long bone approximately 6 inches (15 cm) long that serves as a strut between the shoulder blade and the sternum (breastbone). There are two clavicles, one on the left and one on the right. The clavicle is the only long bone in the body that lies horizontally. Together with the shoulder blade, it makes up the shoulder girdle. It is a anteriorly visible bone, and in people who have less fat in this region, the location of the bone is clearly visible, as it creates a bulge in the skin. It receives its name from the Latin clavicula, because the bone rotates along its axis like a key when the shoulder is abducted. The clavicle is the most commonly fractured bone. It can easily be fractured by impacts to the shoulder from the force of falling on outstretched arms or by a direct hit.
Bone marrow is a semi-solid tissue found within the spongy portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production. It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a man weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow.
Bone Thugs-n-Harmony is an American hip hop group composed of rappers Bizzy Bone, Wish Bone, Layzie Bone, Krayzie Bone, and Flesh-n-Bone. The group was signed to fellow American rapper Eazy-E‘s Ruthless Records in late 1993, when they debuted with their EP Creepin on ah Come Up. The EP included their breakout hit single "Thuggish Ruggish Bone". In 1995, the group released its second album E. 1999 Eternal, which included hits "1st of tha Month" and "East 1999". Their hit song "Tha Crossroads", a tribute to then-recently deceased mentor Eazy-E, won a Grammy Award in 1997.
A bone tumor is an abnormal growth of tissue in bone, traditionally classified as noncancerous (benign) or cancerous (malignant). Cancerous bone tumors usually originate from a cancer in another part of the body such as from lung, breast, thyroid, kidney and prostate. There may be a lump, pain, or neurological signs from pressure. A bone tumor might present with a pathologic fracture. Other symptoms may include fatigue, fever, weight loss, anemia and nausea. Sometimes there are no symptoms and the tumour is found when investigating another problem.
The human musculoskeletal system is an organ system that gives humans the ability to move using their muscular and skeletal systems. The musculoskeletal system provides form, support, stability, and movement to the body.
Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to interruption of the blood supply. Early on, there may be no symptoms. Gradually joint pain may develop which may limit the ability to move. Complications may include collapse of the bone or nearby joint surface.
Bones is an American crime procedural comedy-drama television series created by Hart Hanson for the Fox Broadcasting Company. It premiered on September 13, 2005, and concluded on March 28, 2017, airing for 246 episodes over 12 seasons. The show is based on forensic anthropology and forensic archaeology, with each episode focusing on a Federal Bureau of Investigation (FBI) case file concerning the mystery behind human remains brought by FBI Special Agent Seeley Booth to Temperance "Bones" Brennan, a forensic anthropologist. It also explores the personal lives of the characters. The rest of the main cast includes Michaela Conlin, T. J. Thyne, Eric Millegan, Jonathan Adams, Tamara Taylor, John Francis Daley, and John Boyd.
A hand is a prehensile, multi-fingered appendage located at the end of the forearm or forelimb of primates such as humans, chimpanzees, monkeys, and lemurs. A few other vertebrates such as the koala are often described as having "hands" instead of paws on their front limbs. The raccoon is usually described as having "hands" though opposable thumbs are lacking.
Englitazone is a hypoglycemic agent of thiazolidinedione (glitazone) class.
In anatomy, the mandible, lower jaw or jawbone is the largest, strongest and lowest bone in the human facial skeleton. It forms the lower jaw and holds the lower teeth in place. The mandible sits beneath the maxilla. It is the only movable bone of the skull. It is connected to the temporal bones by the temporomandibular joints.
Shadow and Bone is an American fantasy streaming television series developed by Eric Heisserer for Netflix. It is based on two series of books in the Grishaverse by Leigh Bardugo, the Shadow and Bone trilogy and the Six of Crows duology. All eight episodes of the first season premiered on April 23, 2021. In June 2021, the series was renewed for a second season, also consisting of eight episodes which is scheduled to premiere on March 16, 2023.
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