Metahexamide

Metahexamide
Names
	Preferred IUPAC name 3-Amino-N-(cyclohexylcarbamoyl)-4-methylbenzene-1-sulfonamide
Identifiers
CAS Number	565-33-3 ;
3D model (JSmol)	Interactive image ;
ChEMBL	ChEMBL507419 ;
ChemSpider	10785 ;
ECHA InfoCard	100.008.434
KEGG	D07117 ;
PubChem CID	11259 ;
UNII	T3U6F5D722 ;
CompTox Dashboard (EPA)	DTXSID3023267 ;
	InChI InChI=1S/C14H21N3O3S/c1-10-7-8-12(9-13(10)15)21(19,20)17-14(18)16-11-5-3-2-4-6-11/h7-9,11H,2-6,15H2,1H3,(H2,16,17,18) Key: XXYTXQGCRQLRHA-UHFFFAOYSA-N ; InChI=1/C14H21N3O3S/c1-10-7-8-12(9-13(10)15)21(19,20)17-14(18)16-11-5-3-2-4-6-11/h7-9,11H,2-6,15H2,1H3,(H2,16,17,18) Key: XXYTXQGCRQLRHA-UHFFFAOYAB;
	SMILES CC1=C(C=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2)N;
Properties
Chemical formula	C14H21N3O3S
Molar mass	311.4 g/mol
Pharmacology
ATC code	A10BB10 ( WHO )
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Last updated January 01, 2026

Metahexamide (INN) is an anti-diabetic drug from the group of sulfonylureas. It is long-acting and belongs to the first-generation cyclohexyl-containing sulfonylureas. It was first described in 1959.^[1]

References

↑ Moss JM, Delawter D (September 1959). "Metahexamide in diabetes therapy". Ann NY Acad Sci. 82 (2): 614–7. Bibcode:1959NYASA..82..614M. doi:10.1111/j.1749-6632.1959.tb44940.x. PMID 14424617.

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[1] Moss JM, Delawter D (September 1959). "Metahexamide in diabetes therapy". Ann NY Acad Sci. 82 (2): 614–7. Bibcode:1959NYASA..82..614M. doi:10.1111/j.1749-6632.1959.tb44940.x. PMID 14424617.

[1]

Names

Preferred IUPAC name 3-Amino-N-(cyclohexylcarbamoyl)-4-methylbenzene-1-sulfonamide
Identifiers
CAS Number	565-33-3 ^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL507419 ^N
ChemSpider	10785 ^N
ECHA InfoCard	100.008.434
KEGG	D07117 ^N
PubChem CID	11259
UNII	T3U6F5D722 ^Y
CompTox Dashboard (EPA)	DTXSID3023267
InChI InChI=1S/C14H21N3O3S/c1-10-7-8-12(9-13(10)15)21(19,20)17-14(18)16-11-5-3-2-4-6-11/h7-9,11H,2-6,15H2,1H3,(H2,16,17,18)^N Key: XXYTXQGCRQLRHA-UHFFFAOYSA-N^N InChI=1/C14H21N3O3S/c1-10-7-8-12(9-13(10)15)21(19,20)17-14(18)16-11-5-3-2-4-6-11/h7-9,11H,2-6,15H2,1H3,(H2,16,17,18) Key: XXYTXQGCRQLRHA-UHFFFAOYAB
SMILES CC1=C(C=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2)N
Properties
Chemical formula	C₁₄H₂₁N₃O₃S
Molar mass	311.4 g/mol
Pharmacology
ATC code	A10BB10 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references