Norverapamil

Norverapamil
Names
	IUPAC name (RS)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-isopropylpentanenitrile
Identifiers
CAS Number	67018-85-3 ;
3D model (JSmol)	Interactive image ;
ChEBI	CHEBI:132050 ;
ChemSpider	94724 ;
ECHA InfoCard	100.060.476
EC Number	266-544-8;
PubChem CID	104972 ;
UNII	957Z3K3R56 ;
CompTox Dashboard (EPA)	DTXSID80873799 ;
	InChI InChI=1S/C26H36N2O4/c1-19(2)26(18-27,21-9-11-23(30-4)25(17-21)32-6)13-7-14-28-15-12-20-8-10-22(29-3)24(16-20)31-5/h8-11,16-17,19,28H,7,12-15H2,1-6H3 Key: UPKQNCPKPOLASS-UHFFFAOYSA-N ; InChI=1/C26H36N2O4/c1-19(2)26(18-27,21-9-11-23(30-4)25(17-21)32-6)13-7-14-28-15-12-20-8-10-22(29-3)24(16-20)31-5/h8-11,16-17,19,28H,7,12-15H2,1-6H3 Key: UPKQNCPKPOLASS-UHFFFAOYAQ;
	SMILES CC(C)C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC;
Properties
Chemical formula	C26H36N2O4
Molar mass	440.584 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Last updated March 01, 2025

Norverapamil is a calcium channel blocker. It is the main active metabolite of verapamil.^[1]

References

↑ Christiane Pauli-Magnus, Oliver von Richter, Oliver Burk, Anja Ziegler, Thomas Mettang, Michel Eichelbaum and Martin F. Fromm (2000). "Characterization of the Major Metabolites of Verapamil as Substrates and Inhibitors of P-glycoprotein". Journal of Pharmacology and Experimental Therapeutics. 293 (2): 376–382. PMID 10773005.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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[1] Christiane Pauli-Magnus, Oliver von Richter, Oliver Burk, Anja Ziegler, Thomas Mettang, Michel Eichelbaum and Martin F. Fromm (2000). "Characterization of the Major Metabolites of Verapamil as Substrates and Inhibitors of P-glycoprotein". Journal of Pharmacology and Experimental Therapeutics. 293 (2): 376–382. PMID 10773005.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[1]

Names

IUPAC name (RS)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-isopropylpentanenitrile
Identifiers
CAS Number	67018-85-3 ^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:132050 ^N
ChemSpider	94724 ^N
ECHA InfoCard	100.060.476
EC Number	266-544-8
PubChem CID	104972
UNII	957Z3K3R56 ^Y
CompTox Dashboard (EPA)	DTXSID80873799
InChI InChI=1S/C26H36N2O4/c1-19(2)26(18-27,21-9-11-23(30-4)25(17-21)32-6)13-7-14-28-15-12-20-8-10-22(29-3)24(16-20)31-5/h8-11,16-17,19,28H,7,12-15H2,1-6H3^N Key: UPKQNCPKPOLASS-UHFFFAOYSA-N^N InChI=1/C26H36N2O4/c1-19(2)26(18-27,21-9-11-23(30-4)25(17-21)32-6)13-7-14-28-15-12-20-8-10-22(29-3)24(16-20)31-5/h8-11,16-17,19,28H,7,12-15H2,1-6H3 Key: UPKQNCPKPOLASS-UHFFFAOYAQ
SMILES CC(C)C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
Properties
Chemical formula	C₂₆H₃₆N₂O₄
Molar mass	440.584 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references