Pranidipine

Pranidipine
Names
	Preferred IUPAC name Methyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
	Other names 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O5-methyl O3-[(E)-3-phenylprop-2-enyl] ester
Identifiers
CAS Number	99522-79-9 ;
3D model (JSmol)	Interactive image ;
ChEMBL	ChEMBL1096842 ;
ChemSpider	4940726 ;
MeSH	C048161
PubChem CID	6436048 ;
UNII	9DES9QVH58 ;
CompTox Dashboard (EPA)	DTXSID00875518 ;
	InChI InChI=1S/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+ Key: XTFPDGZNWTZCMF-DHZHZOJOSA-N ; InChI=1/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+ Key: XTFPDGZNWTZCMF-DHZHZOJOBA;
	SMILES CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC;
Properties
Chemical formula	C25H24N2O6
Molar mass	448.46786
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Last updated January 01, 2026

Pranidipine is a calcium channel blocker. It is a long acting calcium channel antagonist of the dihydropyridine group.^[1]

References

↑ Jin Yang; Keisuke Fukuo; Shigeto Morimoto; Tadaaki Niinobu; Toshimitsu Suhara; Toshio Ogihara (2000). "Pranidipine Enhances the Action of Nitric Oxide Released From Endothelial Cells". Hypertension. 35 (1 Pt 1): 82–85. doi: 10.1161/01.hyp.35.1.82 . PMID 10642279.

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[nps01-1] Jin Yang; Keisuke Fukuo; Shigeto Morimoto; Tadaaki Niinobu; Toshimitsu Suhara; Toshio Ogihara (2000). "Pranidipine Enhances the Action of Nitric Oxide Released From Endothelial Cells". Hypertension. 35 (1 Pt 1): 82–85. doi: 10.1161/01.hyp.35.1.82 . PMID 10642279.

[1]

Names

Preferred IUPAC name Methyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Other names 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O⁵-methyl O³-[(E)-3-phenylprop-2-enyl] ester
Identifiers
CAS Number	99522-79-9 ^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1096842 ^N
ChemSpider	4940726 ^N
MeSH	C048161
PubChem CID	6436048
UNII	9DES9QVH58 ^Y
CompTox Dashboard (EPA)	DTXSID00875518
InChI InChI=1S/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+^N Key: XTFPDGZNWTZCMF-DHZHZOJOSA-N^N InChI=1/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+ Key: XTFPDGZNWTZCMF-DHZHZOJOBA
SMILES CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
Properties
Chemical formula	C₂₅H₂₄N₂O₆
Molar mass	448.46786
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references