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Clinical data | |
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Other names | BMS-234303; BMS234303 |
Routes of administration | Topical [1] |
Drug class | ATP-sensitive potassium channel opener; Vasodilator |
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Chemical and physical data | |
Formula | C15H19N5 |
Molar mass | 269.352 g·mol−1 |
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Naminidil (INN , USAN ; developmental code name BMS-234303) is an ATP-sensitive potassium channel opener with vasodilator activity which was under development as a topical medication for the treatment of androgenic alopecia (pattern hair loss) but was never marketed. [2] [3] [1] The drug was under development by Bristol-Myers Squibb and reached phase 2 clinical trials by 2001. [2] One of the phase 2 trials compared naminidil, minoxidil, and placebo for alopecia. [1] However, no results of the study appear to have been made available. [1] Development of naminidil was discontinued by 2008. [2] In terms of chemical structure, naminidil is a guanidine derivative and is structurally distinct from minoxidil. [2] [4]