Epoetin theta

Last updated

Epoetin theta
Clinical data
Trade names Biopoin, Eporatio
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
PubChem SID
DrugBank
UNII
Chemical and physical data
Formula C815H1317N233O241S5
Molar mass 18396.19 g·mol−1

Epoetin theta, sold under the brand name Biopoin among others, is a form of the human hormone erythropoietin produced using recombinant DNA technology. [1] [2]

Contents

It acts as a short acting erythropoiesis-stimulating agent (ESA) for the treatment of anemia associated with chronic kidney disease and chemotherapy-induced anemia in patients with cancer. [3]

Medical uses

Epoetin theta is indicated for the treatment of symptomatic anemia in adults. [1]

Side effects

The most common side effects include shunt thrombosis (clots that can form in blood vessels of patients on dialysis, a blood clearance technique), headache, hypertension (high blood pressure), hypertensive crisis (sudden, dangerously high blood pressure), skin reactions, arthralgia (joint pain) and influenza (flu)-like illness. [1] Epoetin theta was authorized for medical use in the European Union in October 2009. [1] It is on the World Health Organization's List of Essential Medicines. [4]


References

  1. 1 2 3 4 5 "Biopoin EPAR". European Medicines Agency (EMA). 16 December 2009. Retrieved 26 January 2021. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  2. 1 2 "Eporatio EPAR". European Medicines Agency (EMA). 16 December 2009. Retrieved 26 January 2021. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  3. ↑ Forbes CA, Worthy G, Harker J, Kleijnen J, Kutikova L, Zelek L, Van Belle S (April 2014). "Dose efficiency of erythropoiesis-stimulating agents for the treatment of patients with chemotherapy-induced anemia: a systematic review". Clinical Therapeutics. 36 (4): 594–610. doi:10.1016/j.clinthera.2014.02.007. PMID   24656152.
  4. ↑ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl: 10665/345533 . WHO/MHP/HPS/EML/2021.02.

attribution contains material copied from Biopoin | European Medicines Agency https://www.ema.europa.eu/en/medicines/human/EPAR/biopoin 2021

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.