Inferior mesenteric lymph nodes

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Inferior mesenteric lymph nodes
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Lymphatics of colon. (Inferior mesenteric labeled at bottom center.)
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Details
System Lymphatic system
Drains to preaortic lymph node
Identifiers
Latin nodi lymphoidei mesenterici inferiores
Anatomical terminology

The inferior mesenteric lymph nodes consist of:

Structure

The inferior mesenteric lymph nodes are lymph nodes present throughout the hindgut. [1]

Contents

Function

The inferior mesenteric lymph nodes drain structures related to the hindgut. The lymph nodes drain into the superior mesenteric lymph nodes and ultimately to the preaortic lymph nodes. [1] Lymph nodes surrounding the inferior mesenteric artery drain directly into the preaortic nodes. [1]

They drain the descending colon and sigmoid parts of the colon and the upper part of the rectum.

Clinical significance

Colorectal cancer may metastasise to the inferior mesenteric lymph nodes. For this reason, the inferior mesenteric artery may be removed in people with lymph node-positive cancer. [2] This has been proposed since at least 1908, by surgeon William Ernest Miles. [3]

Additional images

Related Research Articles

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Duodenum First section of the small intestine

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Sigmoid colon

The sigmoid colon is the part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 35–40 centimetres (14–16 in) in length. The loop is typically shaped like a Greek letter sigma (ς) or Latin letter S. This part of the colon normally lies within the pelvis, but due to its freedom of movement it is liable to be displaced into the abdominal cavity.

Abdominal pain Stomach aches

Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues.

Mesentery Contiguous fold of tissues that supports the intestines

The mesentery is an organ that attaches the intestines to the posterior abdominal wall in humans and is formed by the double fold of peritoneum. It helps in storing fat and allowing blood vessels, lymphatics, and nerves to supply the intestines, among other functions.

Pancreaticoduodenectomy

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Periaortic lymph nodes

The periaortic lymph nodes are a group of lymph nodes that lie in front of the lumbar vertebrae near the aorta. These lymph nodes receive drainage from the gastrointestinal tract and the abdominal organs.

Inferior mesenteric artery

In human anatomy, the inferior mesenteric artery, often abbreviated as IMA, is the third main branch of the abdominal aorta and arises at the level of L3, supplying the large intestine from the distal transverse colon to the upper part of the anal canal. The regions supplied by the IMA are the descending colon, the sigmoid colon, and part of the rectum.

Inferior mesenteric vein

In human anatomy, the inferior mesenteric vein (IMV) is a blood vessel that drains blood from the large intestine. It usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV).

Middle rectal artery

The middle rectal artery is an artery in the pelvis that supplies blood to the rectum.

Ischemic colitis Medical condition

Ischemic colitis is a medical condition in which inflammation and injury of the large intestine result from inadequate blood supply. Although uncommon in the general population, ischemic colitis occurs with greater frequency in the elderly, and is the most common form of bowel ischemia. Causes of the reduced blood flow can include changes in the systemic circulation or local factors such as constriction of blood vessels or a blood clot. In most cases, no specific cause can be identified.

Left colic artery Artery

The left colic artery is a branch of the inferior mesenteric artery.

Inferior mesenteric plexus

The inferior mesenteric plexus is derived chiefly from the aortic plexus.

Midgut Embryonic structure from which most of the intestines develop

The midgut is the portion of the embryo from which most of the intestines develop. After it bends around the superior mesenteric artery, it is called the "midgut loop". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon.

Descending colon

In the anatomy of humans and homologous primates, the descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. The function of the descending colon in the digestive system is to store the remains of digested food that will be emptied into the rectum.

Superior rectal artery

The superior rectal artery is an artery that descends into the pelvis to supply blood to the rectum.

Preaortic lymph nodes

The preaortic lymph nodes lie in front of the aorta, and may be divided into celiac lymph nodes, superior mesenteric lymph nodes, and inferior mesenteric lymph nodes groups, arranged around the origins of the corresponding arteries.

Superior mesenteric lymph nodes

The superior mesenteric lymph nodes may be divided into three principal groups:

Hepatic lymph nodes Lymph nodes on the common hepatic artery

The hepatic lymph nodes consist of the following groups:

Rectum Final portion of the large intestine

The rectum is the final straight portion of the large intestine in humans and some other mammals, and the gut in others. The adult human rectum is about 12 centimetres (4.7 in) long, and begins at the rectosigmoid junction at the level of the third sacral vertebra or the sacral promontory depending upon what definition is used. Its diameter is similar to that of the sigmoid colon at its commencement, but it is dilated near its termination, forming the rectal ampulla. It terminates at the level of the anorectal ring or the dentate line, again depending upon which definition is used. In humans, the rectum is followed by the anal canal which is about 4 centimetres (1.6 in) long, before the gastrointestinal tract terminates at the anal verge. The word rectum comes from the Latin rectumintestinum, meaning straight intestine.

References

PD-icon.svgThis article incorporates text in the public domain from page 710 of the 20th edition of Gray's Anatomy (1918)

  1. 1 2 3 Drake, Richard L.; Vogl, Wayne; Tibbitts, Adam W.M. Mitchell; illustrations by Richard; Richardson, Paul (2005). Gray's anatomy for students. Philadelphia: Elsevier/Churchill Livingstone. p. 307. ISBN   978-0-8089-2306-0.{{cite book}}: CS1 maint: multiple names: authors list (link)
  2. Kim, J.C.; Lee, K.H.; Yu, C.S.; Kim, H.C.; Kim, J.R.; Chang, H.M.; Kim, J.H.; Kim, J.S.; Kim, T.W. (2004). "The clinicopathological significance of inferior mesenteric lymph node metastasis in colorectal cancer". European Journal of Surgical Oncology. 30 (3): 271–279. doi:10.1016/j.ejso.2003.12.002. PMID   15028308.
  3. Pezim, M. E.; Nicholls, R. J. (1984). "Survival after high or low ligation of the inferior mesenteric artery during curative surgery for rectal cancer". Annals of Surgery. 200 (6): 729–733. doi:10.1097/00000658-198412000-00010. PMC   1250590 . PMID   6508403.