| Name | Chapter | Notable | Reference |
|---|
| William B. Allison | Hudson | U.S. Senator, U.S. House of Representatives | [3] [32] |
| Herbert Ames | Amherst | Financial director, League of Nations; member, Canadian Parliament | [32] |
| Robert R. Barry | Hamilton | U.S. House of Representatives | [7] |
| Carroll L. Beedy | Yale | U.S. House of Representatives | [7] |
| Taul Bradford | Alabama | U.S. House of Representatives | [2] |
| Joshua Chamberlain | Bowdoin | Governor of Maine, president of Bowdoin College | [81] [3] |
| Alfred C. Chapin | Williams | U.S. House of Representatives, mayor of Brooklyn | [7] |
| Ray P. Chase | Minnesota | U.S. House of Representatives and Minnesota State Auditor | [7] |
| Patrick W. Cullinan | Cornell | New York politician | [7] |
| Dwight F. Davis | Harvard | Secretary of War, Governor-General of the Philippines | [7] |
| William Dennison Jr. | Miami | governor of Ohio, United States Postmaster General | [3] |
| John S. Dyson | Cornell | Deputy mayor of New York City; Commissioner of Commerce | [82] |
| Charles S. Fairchild | Harvard | U.S. Secretary of the Treasury, Attorney General of New York | [7] [3] |
| James Rudolph Garfield | Williams | U.S. Secretary of the Interior | [3] |
| George Reginald Geary | Toronto | Minister of Justice, mayor of Toronto, member of Canadian Parliament | [2] |
| Frederick H. Gillett | Amherst | Speaker of the U.S. House of Representatives | [32] |
| William S. Groesbeck | Miami | U.S. House of Representatives | [2] |
| Clarence E. Hancock | Middletown | U.S. House of Representatives | [7] |
| John Philip Hill | Johns Hopkins | U.S. House of Representatives | [7] |
| Phineas Hitchcock | Williams | U.S. Senate | [3] [32] |
| Richard D. Hubbard | Yale | governor of Connecticut, U.S. House of Representatives | [3] |
| Thomas Jenckes | Brunonian | U.S. House of Representatives | [63] |
| Otto Kerner Jr. | Brunonian | Governor of Illinois, circuit judge of the U.S. Court of Appeals | [7] |
| Goodwin Knight | Stanford | governor of California | [7] |
| Bill Luther | Minnesota | U.S. House of Representatives | [83] |
| Medill McCormick | Yale | U.S. Senate, U.S. House of Representatives | [32] |
| Hunter Meighan | Columbia | Politician and lawyer | [84] |
| William Henry Moore | Toronto | member of Canadian Parliament | [85] |
| Marcus Morton | Brunonian | chief justice of the Massachusetts Supreme Judicial Court | [63] |
| Edward Follansbee Noyes | Dartmouth | governor of Ohio, U.S. Ambassador to France | [3] [32] |
| J. Van Vechten Olcott | Manhattan | U.S. House of Representatives | [7] |
| Leonard Outerbridge | Toronto | Lieutenant Governor of Newfoundland, Companion of the Order of Canada | [34] |
| Charles H. Percy | Chicago | U.S. senator, president of the Bell & Howell Corporation | [7] |
| George E. Pugh | Miami | U.S. Senate | [3] [32] |
| Joseph V. Quarles | Peninsular | U.S. Senate, U.S. district judge for the Eastern District of Wisconsin | [3] [32] |
| James Burton Reynolds | Dartmouth | Assistant Secretary of the Treasury | [7] |
| Ellis H. Roberts | Yale | U.S. House of Representatives, Treasurer of the United States | [7] |
| Franklin D. Roosevelt | Harvard | President of the United States | [7] |
| Theodore Roosevelt | Harvard | President of the United States | [7] [3] |
| George Washington Shonk | Middletown | U.S. House of Representatives | [2] |
| Herbert B. Shonk | Middletown | New York State Assembly, attorney | [7] |
| Watson G. Squire | Middletown | U.S. Senator, Ohio Attorney General | [3] [32] |
| Thomas Sweeney | | U.S. Senator and U.S. House of Representatives | [7] |
| Allen T. Treadway | Amherst | U.S. House of Representatives | [7] |
| Fred Upton | Peninsular | U.S. House of Representatives | [7] |
| Aldonijah Welch | Peninsular | U.S. Senator, president of Iowa State Agricultural College (now Iowa State University) | [3] [32] |
| Ashbel P. Willard | Hamilton | Governor of Indiana | [3] |
| John S. Wold | Union | U.S. House of Representatives, geologist | [86] |