Urologic disease

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Urologic diseases or conditions include urinary tract infections, kidney stones, bladder control problems, and prostate problems, among others. Some urologic conditions do not affect a person for that long and some are lifetime conditions. [1] Kidney diseases are normally investigated and treated by nephrologists, while the specialty of urology deals with problems in the other organs. Gynecologists may deal with problems of incontinence in women.

Contents

Diseases of other bodily systems also have a direct effect on urogenital function. For instance, it has been shown that protein released by the kidneys in diabetes mellitus sensitizes the kidney to the damaging effects of hypertension. [2] Diabetes also can have a direct effect on urination due to peripheral neuropathies, which occur in some individuals with poorly controlled diabetics.

Kidney disease

Kidney disease, or renal disease, also known as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation. Inflammation can be diagnosed by blood tests. Nephrosis is non-inflammatory kidney disease. Nephritis and nephrosis can give rise to nephritic syndrome and nephrotic syndrome respectively. Kidney disease usually causes a loss of kidney function to some degree and can result in kidney failure, the complete loss of kidney function. Kidney failure is known as the end-stage of kidney disease, where dialysis or a kidney transplant is the only treatment option.

Chronic kidney disease causes the gradual loss of kidney function over time. Acute kidney disease is now termed acute kidney injury and is marked by the sudden reduction in kidney function over seven days. About one in eight Americans (as of 2007) has chronic kidney disease. [3] Primary renal cell carcinomas as well as metastatic cancers can affect the kidney.

Kidney failure

Kidney failure is defined by functional impairment of the kidney, whereas the kidneys are functioning at 15% or less than normal capability. [1] It is divided into acute kidney failure (cases that develop rapidly) and chronic kidney failure (those that are long term). [4] Symptoms may include leg swelling, feeling tired, vomiting, loss of appetite, and confusion. [1] Complications of acute disease may include uremia, high blood potassium, and volume overload. [5] Complications of chronic disease may include heart disease, high blood pressure, and anemia. [6] [7]

Pre-renal kidney failure refers to impairment of supply of blood to the functional nephrons including renal artery stenosis. Intrinsic kidney diseases are the classic diseases of the kidney including drug toxicity and nephritis. Post-renal kidney failure is outlet obstruction after the kidney, such as a kidney stone or prostatic bladder outlet obstruction. Kidney failure may require medication, dietary lifestyle modifications, and dialysis.

Non-renal urinary tract disease

Structural and or traumatic changes in the urinary tract can lead to hemorrhage, functional blockage or inflammation. Colonization by bacteria, protozoa or fungi can cause infection. Uncontrolled cell growth can cause neoplasia. The term "uropathy" refers to a disease of the urinary tract, while "nephropathy" refers to a disease of the kidney. For example:

Testing

Radiology based testing

References

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