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This is a list of aviation-related events from 2010.
 The deadliest crash of this year was Air India Express Flight 812, a Boeing 737 which crashed in a runway overrun at Mangalore, India on 22 May, killing 158 of the 166 people on board. The deadliest military aircraft crash of this year was the crash of a Polish Air Force Tu-154 in Smolensk, Russia on 10 April, killing all 96 on board.