DUSP15

Last updated
DUSP15
Protein DUSP15 PDB 1yz4.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DUSP15 , VHY, C20orf57, dual specificity phosphatase 15
External IDs OMIM: 616776; MGI: 1934928; HomoloGene: 33586; GeneCards: DUSP15; OMA:DUSP15 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_177991
NM_001012644
NM_080611
NM_001320478
NM_001320479

Contents

NM_001159376
NM_145744

RefSeq (protein)

NP_001012662
NP_001307407
NP_001307408
NP_542178
NP_817130

NP_001152848
NP_665687

Location (UCSC) Chr 20: 31.85 – 31.87 Mb Chr 2: 152.78 – 152.79 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Dual specificity protein phosphatase 15 is an enzyme that in humans is encoded by the DUSP15 gene. [5] [6]

The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phosphatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants, encoding two different isoforms have been found for this gene. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000149599 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042662 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Alonso A, Narisawa S, Bogetz J, Tautz L, Hadzic R, Huynh H, Williams S, Gjorloff Wingren A, Bremer MC, Holsinger LJ, Millan JL, Mustelin T (Jul 2004). "VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX". J Biol Chem. 279 (31): 32586–91. doi: 10.1074/jbc.M403442200 . PMID   15138252.
  6. 1 2 "Entrez Gene: DUSP15 dual specificity phosphatase 15".

Further reading