HAS3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | HAS3 , hyaluronan synthase 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 602428; MGI: 109599; HomoloGene: 68461; GeneCards: HAS3; OMA:HAS3 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Hyaluronan synthase 3 is an enzyme that in humans is encoded by the HAS3 gene. [5] [6] [7]
The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Two transcript variants encoding different isoforms have been found for this gene. [7]
Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334.
Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene.
Disintegrin and metalloproteinase domain-containing protein 15 is an enzyme that in humans is encoded by the ADAM15 gene.
The alpha-1B adrenergic receptor (α1B-adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it. The crystal structure of the α1B-adrenergic receptor has been determined in complex with the inverse agonist (+)-cyclazosin.
Sphingosine-1-phosphate receptor 3 also known as S1PR3 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P3.
A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene.
Matrix metalloproteinase-26 also known as matrilysin-2 and endometase is an enzyme that in humans is encoded by the MMP26 gene.
Hyaluronan synthase 2 is an enzyme that in humans is encoded by the HAS2 gene.
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase is an enzyme that in humans is encoded by the ST8SIA1 gene.
Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene.
Collagen alpha-2(VIII) chain is a protein that in humans is encoded by the COL8A2 gene. Mutations of the gene are linked to posterior polymorphous dystrophy type 2.
Stabilin-1 is a protein that in humans is encoded by the STAB1 gene.
Fibroblast growth factor 13 is a protein that in humans is encoded by the FGF13 gene.
Fibroblast growth factor 6 is a protein that in humans is encoded by the FGF6 gene.
Fibroblast growth factor 12 is a protein that in humans is encoded by the FGF12 gene.
Lactosylceramide 4-alpha-galactosyltransferase is an enzyme that in humans is encoded by the A4GALT gene.
Fibroblast growth factor 17 is a protein that in humans is encoded by the FGF17 gene.
Disintegrin and metalloproteinase domain-containing protein 28 is an enzyme that in humans is encoded by the ADAM28 gene.
Chondroitin sulfate synthase 1 is an enzyme that in humans is encoded by the CHSY1 gene.
Matrix metalloproteinase 15 also known as MMP15 is an enzyme that in humans is encoded by the MMP15 gene.