Highway 5 or the Trans-Samaria Highway, is one of Israel's main highways, connecting the Mediterranean coast immediately north of Tel Aviv with the central Sharon plain and eastwards to Ariel and other Israeli settlements in the northern West Bank.
Highway 1 is the main highway in Israel, connecting Tel Aviv and Jerusalem, and continuing eastwards to the Jordan Valley in the West Bank.
The Malakhi Junction, also known as Qastina for the Arab village which once stood there, is a major road junction in Israel, between Highway 40 and 3. It is located on the 37th kilometer of Highway 3.
Route 443 is also known as Ma'ale Beit Horon, following the ancient east-west trade route connecting the Via Maris and the Way of the Patriarchs. It is the main highway connecting Tel Aviv and Gush Dan with Jerusalem via Modi'in. While technically listed as a regional road, it is, for the most part, a divided, four-lane highway which utilizes some grade separation and interchanges, as well as major at-grade intersections, and thus is not classified as a motorway, even though there is a short motorway section on its western end, connecting it to westbound Highway 1.
Be'er Tuvia Regional Council, is a regional council in the Southern District of Israel.
Mateh Yehuda Regional Council is a regional council in the Jerusalem District of Israel. In 2024 it was home to 51,125 people.
Highway 7 is a highway in the South District of Israel from Ashdod to Yad Binyamin. It connects the Port of Ashdod with the Trans-Israel Highway.
Highway 12 is a single carriageway road in the South District of Israel. It surrounds the mountains of Eilat from the north and west, and it connects Eilat to Highway 10 and Highway 40, which lead toward central Israel. Highway 10 continues north toward the Gaza Strip, whereas Highway 40 proceeds to Beersheba via Mizpe Ramon.
Highway 25 is a rural highway in southern Israel. It begins northwest of Nahal Oz at the border with the Gaza Strip, and it passes through Netivot, Beersheba and Dimona. It continues southeast toward Arava Junction, where it meets Highway 90. Its length is estimated by the Israeli Department of Transportation as 172 km and 780 meters.
Highway 38 is an arterial road in the low plains of Judea in Israel. It serves as the main access route to Beit Shemesh and as a main north–south route in the region. Along the route are many nature preserves and archeological sites.
Highway 41 is an arterial road in south-central Israel. It connects Highway 4 and Highway 7 to the Port of Ashdod. The designation "41" also applied to the continuation of the road eastward to Gedera until that section of the road was upgraded and renamed "7".
Route 293 is a rural road that connects Highway 40 to Netivot and to Route 34 and Highway 25. Many Kibbutzim and Moshavim are along its path.
Yoav Regional Council is a regional council in the Southern District of Israel. It is located near the cities of Kiryat Gat, Kiryat Malakhi and Ashkelon. It was founded in 1952, covering an area of 230,000 dunams (230 km2), with a population of about 5,300.
Highway 99 is an east-west highway in the Finger of the Galilee in far northeast of Israel and the Golan Heights. It begins in the west at HaMetzodot junction in Kiryat Shmona, and it ends in the east at the Druze city of Mas'ade. After it reaches the Banias tributary, the road follows the path of Sa'ar River. Highway 99 is 24 km long.
Hof Ashkelon Regional Council is a regional council in the Southern District of Israel. As of the year 2019, its population is around 18,000.
Route 411, is the designation of a regional route in the Shephelah region in Israel running southeasterly consolidating previous local roads and new construction. The western section begins at Highway 42 near Kfar Gevirol in western Rehovot and continues just past Route 410. The central section, completed in June 2014, continues to the entrance of Kvutzat Shiller. The eastern section begins just short of Highway 40 south of Rehovot and terminates at Highway 3 towards Jerusalem, bypassing the towns of Kiryat Ekron and Mazkeret Batya.
Route 386 is a road in Israel that runs from Tzur Hadassah to Jerusalem.
Highway 45 is the official designation of a 3.3 km stretch of road forming a continuous connection between Route 443 from the Tel Aviv Metropolitan Area and Highway 50 to central Jerusalem and a 1.4 km spur serving the Atarot Industrial Park.
The Ashkelon Subdistrict is the northern of the two sub-districts in Israel's Southern District. Its population is more than half a million. It is an important region for manufacturing including electricity production and water desalination, agriculture, transportation, tourism, and trade.
Highway 333, also known as Ben-Gurion Boulevard, is a highway in West Jerusalem. It is the main entrance to the city through Givat Shaul. In the past, the road was part of Highway 1 until the opening of Yitzhak Shamir Road and the diverting of Highway 1 onto it. However, it is often colloquially still referred to as part of the Jerusalem–Tel Aviv Route.
